Methylamp™ DNA 修饰试剂盒是一整套优化的试剂，旨在转化 DNA，以便在下游应用中检测 5-甲基胞嘧啶，用于基因特异性 DNA 甲基化分析。该DNA 修饰试剂盒具有以下优点和特点：
- 总时间少于 2 小时。
- 未甲基化胞嘧啶转化为尿嘧啶/胸腺嘧啶的转化率为 99.9%
- 修饰过程中 DNA 的降解极低，可防止超过 90% 的 DNA 损失。
- 只需 50 pg 的起始 DNA，相当于约 20 个细胞。
- 极其简单、稳定且可靠的亚硫酸氢钠转化方案。
- 适用于亚硫酸氢盐测序（直接和克隆）、下一代测序、焦磷酸测序、PCR（实时、终点、甲基化特异性）、COBRA（联合亚硫酸氢盐限制性分析）和基于甲基化的微阵列芯片。
- 与基于 Illumina 的工作流程高度兼容。
艾美捷提供的Epigentek品牌的DNA 修饰试剂盒用于对 DNA 进行稳定的化学亚硫酸氢盐转化，用于甲基化胞嘧啶分析。
| 产品名称 | 货号 | 规格 |
| Methylamp™ DNA 修饰试剂盒
Methylamp DNA Modification Kit |
P-1001 | 40 reactions
80 reactions |
DNA 修饰试剂盒 221篇文献引用：
| 标题 | 作者 | 杂志名称 |
| LINE-1 hypomethylation in spermatozoa is associated with Bisphenol A exposure. | Miao M, Zhou X, Li Y, Zhang O, Zhou Z, Li T, Yuan W, Li R, Li DK | Andrology |
| Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation. | Kang KA, Piao MJ, Kim KC, Kang HK, Chang WY, Park IC, Keum YS, Surh YJ, Hyun JW | Cell Death Dis |
| Noninvasive prenatal detection of fetal trisomy 18 by epigenetic allelic ratio analysis in maternal plasma: Theoretical and empirical considerations. | Tong YK, Ding C, Chiu RW, Gerovassili A, Chim SS, Leung TY, Leung TN, Lau TK, Nicolaides KH, Lo YM | Clin Chem |
| EMP3 overexpression is associated with oligodendroglial tumors retaining chromosome arms 1p and 19q. | Li KK, Pang JC, Chung NY, Ng YL, Chan NH, Zhou L, Poon WS, Ng HK | Int J Cancer |
| Steroid-dependent ACTH-produced thymic carcinoid: regulation of POMC gene expression by cortisol via methylation of its promoter region. | Mizoguchi Y, Kajiume T, Miyagawa S, Okada S, Nishi Y, Kobayashi M | Horm Res |
| Methylation status of the SOCS3 gene in human malignant melanomas. | Tokita T, Maesawa C, Kimura T, Kotani K, Takahashi K, Akasaka T, Masuda T | Int J Oncol |
| 4q loss is potentially an important genetic event in MM tumorigenesis: identification of a tumor suppressor gene regulated by promoter methylation at 4q13.3, platelet factor 4. | Cheng SH, Ng MH, Lau KM, Liu HS, Chan JC, Hui AB, Lo KW, Jiang H, Hou J, Chu RW, Wong WS, Chan NP, Ng HK | Blood |
| Regulation and expression of human CYP7B1 in prostate: overexpression of CYP7B1 during progression of prostatic adenocarcinoma. | Olsson M, Gustafsson O, Skogastierna C, Tolf A, Rietz BD, Morfin R, Rane A, Ekström L | Prostate |
| Identification of an upstream promoter of the human somatostatin receptor, hSSTR2, which is controlled by epigenetic modifications. | Torrisani J, Hanoun N, Laurell H, Lopez F, Maoret JJ, Souque A, Susini C, Cordelier P, Buscail L | Endocrinology |
| HIC1 tumour suppressor gene is suppressed in acute myeloid leukaemia and induced during granulocytic differentiation. | Britschgi C, Jenal M, Rizzi M, Mueller BU, Torbett BE, Andres AC, Tobler A, Fey MF, Tschan MP | Br J Haematol |
| Methylation of a conserved intronic CpG island of mouse SF-1 is associated with cell-specific expression of SF-1 in a culture system but not with tissue-specific expression. | Shirohzu H, Okabe T, Gondo S, Tanaka T, Ohe K, Morinaga H, Kawate H, Nomura M, Takayanagi R, Nawata H, Yanase T | Biochem Biophys Res Commun |
| Loss of methylation imprint of Snrpn in postovulatory aging mouse oocyte. | Liang XW, Zhu JQ, Miao YL, Liu JH, Wei L, Lu SS, Hou Y, Schatten H, Lu KH, Sun QY | Biochem Biophys Res Commun |
| Careful exclusion of non-neoplastic brain components is required for an appropriate evaluation of O6-methylguanine-DNA methyltransferase status in glioma: relationship between immunohistochemistry and methylation analysis. | Sasai K, Nodagashira M, Nishihara H, Aoyanagi E, Wang L, Katoh M, Murata J, Ozaki Y, Ito T, Fujimoto S, Kaneko S, Nagashima K, Tanaka S | Am J Surg Pathol |
| Identification of genes that restrict astrocyte differentiation of midgestational neural precursor cells. | Sanosaka T, Namihira M, Asano H, Kohyama J, Aisaki K, Igarashi K, Kanno J, Nakashima K | Neuroscience |
| Patterns of hybrid loss of imprinting reveal tissue- and cluster-specific regulation. | Wiley CD, Matundan HH, Duselis AR, Isaacs AT, Vrana PB | PLoS One |
| ABF-1 is frequently silenced by promoter methylation in follicular lymphoma, diffuse large B-cell lymphoma and Burkitt's lymphoma. | Ushmorov A, Leithäuser F, Ritz O, Barth TF, Möller P, Wirth T | Leukemia |
| Transcriptional repression of the RUNX3/AML2 gene by the t(8;21) and inv(16) fusion proteins in acute myeloid leukemia. | Cheng CK, Li L, Cheng SH, Lau KM, Chan NP, Wong RS, Shing MM, Li CK, Ng MH | Blood |
| Epigenetic events in normal colonic mucosa surrounding colorectal cancer lesions. | Ramírez N, Bandrés E, Navarro A, Pons A, Jansa S, Moreno I, Martínez-Rodenas F, Zárate R, Bitarte N, Monzó M, García-Foncillas J | Eur J Cancer |
| Real-time quantitative PCR analysis of pediatric ependymomas identifies novel candidate genes including TPR at 1q25 and CHIBBY at 22q12-q13. | Karakoula K, Suarez-Merino B, Ward S, Phipps KP, Harkness W, Hayward R, Thompson D, Jacques TS, Harding B, Beck J, Thomas DG, Warr TJ | Genes Chromosomes Cancer |
| Increased gamma-tubulin expression and P16INK4A promoter methylation occur together in preinvasive lesions and carcinomas of the breast. | Liu T, Niu Y, Yu Y, Liu Y, Zhang F | Ann Oncol |
| Changes in gene expression and assessment of DNA methylation in primary human hepatocytes and HepG2 cells exposed to the environmental contaminants-Hexabromocyclododecane and 17-beta oestradiol. | Aniagu SO, Williams TD, Chipman JK | Toxicology |
| Homeobox gene HOPX is epigenetically silenced in human uterine endometrial cancer and suppresses estrogen-stimulated proliferation of cancer cells by inhibiting serum response factor. | Yamaguchi S, Asanoma K, Takao T, Kato K, Wake N | Int J Cancer |
| The tumor suppressor gene hypermethylated in cancer 1 is transcriptionally regulated by E2F1. | Jenal M, Trinh E, Britschgi C, Britschgi A, Roh V, Vorburger SA, Tobler A, Leprince D, Fey MF, Helin K, Tschan MP | Mol Cancer Res |
| Demethylation of LHR in dehydroepiandrosterone-induced mouse model of polycystic ovary syndrome. | Zhu JQ, Zhu L, Liang XW, Xing FQ, Schatten H, Sun QY | Mol Hum Reprod |
| Maternal imprinting during mouse oocyte growth in vivo and in vitro. | Song Z, Min L, Pan Q, Shi Q, Shen W | Biochem Biophys Res Commun |
| Helicobacter pylori causes runx3 gene methylation and its loss of expression in gastric epithelial cells, which is mediated by nitric oxide produced by macrophages. | Katayama Y, Takahashi M, Kuwayama H | Biochem Biophys Res Commun |
| Reprogramming of human fibroblasts to induced pluripotent stem cells under xeno-free conditions. | Rodríguez-Pizà I, Richaud-Patin Y, Vassena R, González F, Barrero MJ, Veiga A, Raya A, Izpisúa Belmonte JC | Stem Cells |
| Aberrant methylation of the THRB gene in tissue and plasma of breast cancer patients. | Ling Y, Xu X, Hao J, Ling X, Du X, Liu X, Zhao X | Cancer Genet Cytogenet |
| Involvement of epigenetically silenced microRNA-181c in gastric carcinogenesis. | Hashimoto Y, Akiyama Y, Otsubo T, Shimada S, Yuasa Y | Carcinogenesis |
| Aberrant DNA methylation of the p57KIP2 gene is a sensitive biomarker for detecting minimal residual disease in diffuse large B cell lymphoma. | Hagiwara K, Li Y, Kinoshita T, Kunishma S, Ohashi H, Hotta T, Nagai H | Leuk Res |
| Generation of histocompatible androgenetic embryonic stem cells using spermatogenic cells. | Zhao Q, Wang J, Zhang Y, Kou Z, Liu S, Gao S | Stem Cells |
| Relation between hypomethylation of long interspersed nucleotide elements and risk of neural tube defects. | Wang L, Wang F, Guan J, Le J, Wu L, Zou J, Zhao H, Pei L, Zheng X, Zhang T | Am J Clin Nutr |
| Characterisation of CpG methylation in the upstream control region of mouse Nat2: evidence for a gene-environment interaction in a polymorphic gene implicated in folate metabolism. | Wakefield L, Boukouvala S, Sim E | Gene |
| Lack of expression of inhibitory KIR3DL1 receptor in patients with natural killer cell-type lymphoproliferative disease of granular lymphocytes. | Gattazzo C, Teramo A, Miorin M, Scquizzato E, Cabrelle A, Balsamo M, Agostini C, Vendrame E, Facco M, Albergoni MP, Trentin L, Vitale M, Semenzato G, Zambello R | Haematologica |
| Depletion of DNMT3A suppressed cell proliferation and restored PTEN in hepatocellular carcinoma cell. | Zhao Z, Wu Q, Cheng J, Qiu X, Zhang J, Fan H | J Biomed Biotechnol |
| Expression and methylation status of the Syk gene in cervical carcinoma. | Zhao S, Sun G, Tony PW, Ma D, Zhao C | Arch Gynecol Obstet |
| Murine folliculogenesis in vitro is stage-specifically regulated by insulin via the Akt signaling pathway. | Zhang P, Chao H, Sun X, Li L, Shi Q, Shen W | Histochem Cell Biol |
| Trans-acting small RNA determines dominance relationships in Brassica self-incompatibility. | Tarutani Y, Shiba H, Iwano M, Kakizaki T, Suzuki G, Watanabe M, Isogai A, Takayama S | Nature |
| MiR-9 downregulates CDX2 expression in gastric cancer cells. | Rotkrua P, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y | Int J Cancer |
| Analysis of oocyte-like cells differentiated from porcine fetal skin-derived stem cells. | Dyce PW, Shen W, Huynh E, Shao H, Villagómez DA, Kidder GM, King WA, Li J | Stem Cells Dev |
| O6-Methylguanine-DNA methyltransferase protein expression by immunohistochemistry in brain and non-brain systemic tumours: systematic review and meta-analysis of correlation with methylation-specific polymerase chain reaction. | Brell M, Ibáñez J, Tortosa A | BMC Cancer |
| Reprogramming of trophoblast stem cells into pluripotent stem cells by Oct4. | Wu T, Wang H, He J, Kang L, Jiang Y, Liu J, Zhang Y, Kou Z, Liu L, Zhang X, Gao S | Stem Cells |
| DNA methylation of germ-cell-specific basic helix-loop-helix (HLH) transcription factors, Sohlh2 and Figla during gametogenesis. | Pan B, Chao H, Chen B, Zhang L, Li L, Sun X, Shen W | Mol Hum Reprod |
| Hypermethylated DAPK in serum DNA of women with uterine leiomyoma is a biomarker not restricted to cancer. | Häfner N, Diebolder H, Jansen L, Hoppe I, Dürst M, Runnebaum IB | Gynecol Oncol |
| SIP1 is downregulated in hepatocellular carcinoma by promoter hypermethylation. | Acun T, Oztas E, Yagci T, Yakicier MC | BMC Cancer |
| Epigenetic inactivation of calcium-sensing receptor in colorectal carcinogenesis. | Hizaki K, Yamamoto H, Taniguchi H, Adachi Y, Nakazawa M, Tanuma T, Kato N, Sukawa Y, Sanchez JV, Suzuki H, Sasaki S, Imai K, Shinomura Y | Mod Pathol |
| Generation of germline-competent rat induced pluripotent stem cells. | Hamanaka S, Yamaguchi T, Kobayashi T, Kato-Itoh M, Yamazaki S, Sato H, Umino A, Wakiyama Y, Arai M, Sanbo M, Hirabayashi M, Nakauchi H | PLoS One |
| Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas. | Botti E, Spallone G, Moretti F, Marinari B, Pinetti V, Galanti S, De Meo PD, De Nicola F, Ganci F, Castrignanò T, Pesole G, Chimenti S, Guerrini L, Fanciulli M, Blandino G, Karin M, Costanzo A | Proc Natl Acad Sci U S A |
| Epigenetic mechanisms of amyloid-β production in anisomycin-treated SH-SY5Y cells. | Guo X, Wu X, Ren L, Liu G, Li L | Neuroscience |
| Bisphenol A exposure modifies methylation of imprinted genes in mouse oocytes via the estrogen receptor signaling pathway. | Chao HH, Zhang XF, Chen B, Pan B, Zhang LJ, Li L, Sun XF, Shi QH, Shen W | Histochem Cell Biol |
| Identification of promoter region methylation patterns of MGMT, CDKN2A, GSTP1, and THBS1 genes in intracranial meningioma patients. | Aydemir F, Yurtcu E, Balci TB, Sahin FI, Gulsen S, Altinors N | Genet Test Mol Biomarkers |
| Epigenetic changes induced by oxidative stress in colorectal cancer cells: methylation of tumor suppressor RUNX3. | Kang KA, Zhang R, Kim GY, Bae SC, Hyun JW | Tumour Biol |
| Effect of neuronal induction on NSE, Tau, and Oct4 promoter methylation in bone marrow mesenchymal stem cells. | Duan P, Zhang Y, Han X, Liu J, Yan W, Xing Y | In Vitro Cell Dev Biol Anim |
| Characterization of bovine induced pluripotent stem cells by lentiviral transduction of reprogramming factor fusion proteins. | Cao H, Yang P, Pu Y, Sun X, Yin H, Zhang Y, Zhang Y, Li Y, Liu Y, Fang F, Zhang Z, Tao Y, Zhang X | Int J Biol Sci |
| Derivation and cardiomyocyte differentiation of induced pluripotent stem cells from heart failure patients. | Zwi-Dantsis L, Huber I, Habib M, Winterstern A, Gepstein A, Arbel G, Gepstein L | Eur Heart J |
| Fetal exposure to bisphenol A affects the primordial follicle formation by inhibiting the meiotic progression of oocytes. | Zhang HQ, Zhang XF, Zhang LJ, Chao HH, Pan B, Feng YM, Li L, Sun XF, Shen W | Mol Biol Rep |
| IBM1, a JmjC domain-containing histone demethylase, is involved in the regulation of RNA-directed DNA methylation through the epigenetic control of RDR2 and DCL3 expression in Arabidopsis. | Fan D, Dai Y, Wang X, Wang Z, He H, Yang H, Cao Y, Deng XW, Ma L | Nucleic Acids Res |
| Growth of mouse oocytes to maturity from premeiotic germ cells in vitro. | Zhang ZP, Liang GJ, Zhang XF, Zhang GL, Chao HH, Li L, Sun XF, Min LJ, Pan QJ, Shi QH, Sun QY, De Felici M, Shen W | PLoS One |
| Unfolded protein response, activated by OASIS family transcription factors, promotes astrocyte differentiation. | Saito A, Kanemoto S, Kawasaki N, Asada R, Iwamoto H, Oki M, Miyagi H, Izumi S, Sanosaka T, Nakashima K, Imaizumi K | Nat Commun |
| Dietary folate deficiency in pseudopregnant mice has no effect on homeobox A10 promoter methylation or expression. | Long C, He J, Liu X, Chen X, Gao R, Wang Y, Ding Y | Reprod Sci |
| Expression and epigenetic dynamics of transcription regulator Lhx8 during mouse oogenesis. | Zhang LJ, Pan B, Chen B, Zhang XF, Liang GJ, Feng YN, Wang LQ, Ma JM, Li L, Shen W | Gene |
| Methylation pattern of oncogene HRAS gene promoter region and its clinical relevance to urocystic tumorigenesis. | Sun XF, Li L, Li XJ, Shen W | Mol Biol Rep |
| Alteration in methylation pattern of oncogene Akt1 promoter region in bladder cancer. | Sun XF, Sun ZY, Pan B, Li L, Shen W | Mol Biol Rep |
| Gadd45a inhibits cell migration and invasion by altering the global RNA expression. | Shan Z, Li G, Zhan Q, Li D | Cancer Biol Ther |
| Exposure to bisphenol A results in a decline in mouse spermatogenesis. | Zhang GL, Zhang XF, Feng YM, Li L, Huynh E, Sun XF, Sun ZY, Shen W | Reprod Fertil Dev |
| 5-aza-2'-deoxycytidine leads to reduced embryo implantation and reduced expression of DNA methyltransferases and essential endometrial genes. | Ding YB, Long CL, Liu XQ, Chen XM, Guo LR, Xia YY, He JL, Wang YX | PLoS One |
| Differential methylation of E2 binding sites in episomal and integrated HPV 16 genomes in preinvasive and invasive cervical lesions. | Chaiwongkot A, Vinokurova S, Pientong C, Ekalaksananan T, Kongyingyoes B, Kleebkaow P, Chumworathayi B, Patarapadungkit N, Reuschenbach M, von Knebel Doeberitz M | Int J Cancer |
| PROX1 overexpression inhibits protein kinase C beta II transcription through promoter DNA methylation. | Hagiwara K, Ito H, Murate T, Miyata Y, Ohashi H, Nagai H | Genes Chromosomes Cancer |
| A high frequency of MSH6 G268A polymorphism and survival association in glioblastoma. | Pei C, Chen H, Jia X, Yan L, Zou Y, Jiang C, Jin H, Kang C, Jiang T, Ren H | Int J Neurosci |
| Long interspersed nucleotide element-1 hypomethylation in folate-deficient mouse embryonic stem cells. | Chang S, Wang L, Guan Y, Shangguan S, Du Q, Wang Y, Zhang T, Zhang Y | J Cell Biochem |
| Characterization and rescue of telomeric abnormalities in ICF syndrome type I fibroblasts. | Yehezkel S, Shaked R, Sagie S, Berkovitz R, Shachar-Bener H, Segev Y, Selig S | Front Oncol |
| Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Aβ production. | Gu X, Sun J, Li S, Wu X, Li L | Neurobiol Aging |
| Altered methylation of IGF2 DMR0 is associated with neural tube defects. | Wu L, Wang L, Shangguan S, Chang S, Wang Z, Lu X, Zhang Q, Wang J, Zhao H, Wang F, Guo J, Niu B, Guo J, Zhang T | Mol Cell Biochem |
| Diethylhexyl phthalate exposure impairs follicular development and affects oocyte maturation in the mouse. | Zhang XF, Zhang LJ, Li L, Feng YN, Chen B, Ma JM, Huynh E, Shi QH, De Felici M, Shen W | Environ Mol Mutagen |
| Codelivery of mTERT siRNA and paclitaxel by chitosan-based nanoparticles promoted synergistic tumor suppression. | Wei W, Lv PP, Chen XM, Yue ZG, Fu Q, Liu SY, Yue H, Ma GH | Biomaterials |
| Multiple-to-multiple relationships between microRNAs and target genes in gastric cancer. | Hashimoto Y, Akiyama Y, Yuasa Y | PLoS One |
| Oxidative stress causes epigenetic alteration of CDX1 expression in colorectal cancer cells. | Zhang R, Kang KA, Kim KC, Na SY, Chang WY, Kim GY, Kim HS, Hyun JW | Gene |
| Promoter hypermethylation of CDKN2A, MGMT, MLH1, and DAPK genes in laryngeal squamous cell carcinoma and their associations with clinical profiles of the patients. | Pierini S, Jordanov SH, Mitkova AV, Chalakov IJ, Melnicharov MB, Kunev KV, Mitev VI, Kaneva RP, Goranova TE | Head Neck |
| Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming. | Gao Y, Chen J, Li K, Wu T, Huang B, Liu W, Kou X, Zhang Y, Huang H, Jiang Y, Yao C, Liu X, Lu Z, Xu Z, Kang L, Chen J, Wang H, Cai T, Gao S | Cell Stem Cell |
| Chromatin accessibility at a STAT3 target site is altered prior to astrocyte differentiation. | Urayama S, Semi K, Sanosaka T, Hori Y, Namihira M, Kohyama J, Takizawa T, Nakashima K | Cell Struct Funct |
| The role of a ginseng saponin metabolite as a DNA methyltransferase inhibitor in colorectal cancer cells. | Kang KA, Kim HS, Kim DH, Hyun JW | Int J Oncol |
| Generation of transgenic rats through induced pluripotent stem cells. | Jiang MG, Li T, Feng C, Fu R, Yuan Y, Zhou Q, Li X, Wan H, Wang L, Li W, Xiao Y, Zhao XY, Zhou Q | J Biol Chem |
| Comprehensive analysis of PTEN status in Sezary syndrome. | Cristofoletti C, Picchio MC, Lazzeri C, Tocco V, Pagani E, Bresin A, Mancini B, Passarelli F, Facchiano A, Scala E, Lombardo GA, Cantonetti M, Caprini E, Russo G, Narducci MG | Blood |
| Compound K, a metabolite of ginseng saponin, inhibits colorectal cancer cell growth and induces apoptosis through inhibition of histone deacetylase activity. | Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Kim HS, Kim DH, Bae SC, Hyun JW | Int J Oncol |
| DNA methylation mediates persistent epileptiform activity in vitro and in vivo. | Machnes ZM, Huang TC, Chang PK, Gill R, Reist N, Dezsi G, Ozturk E, Charron F, O'Brien TJ, Jones NC, McKinney RA, Szyf M | PLoS One |
| Niche-dependent gene expression profile of intratumoral heterogeneous ovarian cancer stem cell populations. | Abelson S, Shamai Y, Berger L, Skorecki K, Tzukerman M | PLoS One |
| Hypomethylation of long interspersed nucleotide element-1 in peripheral mononuclear cells of juvenile systemic lupus erythematosus patients in China. | Huang X, Su G, Wang Z, Shangguan S, Cui X, Zhu J, Kang M, Li S, Zhang T, Wu F, Wang L | Int J Rheum Dis |
| Exposure to diethylhexyl phthalate (DEHP) results in a heritable modification of imprint genes DNA methylation in mouse oocytes. | Li L, Zhang T, Qin XS, Ge W, Ma HG, Sun LL, Hou ZM, Chen H, Chen P, Qin GQ, Shen W, Zhang XF | Mol Biol Rep |
| Di-(2-ethylhexyl) phthalate and bisphenol A exposure impairs mouse primordial follicle assembly in vitro. | Zhang T, Li L, Qin XS, Zhou Y, Zhang XF, Wang LQ, De Felici M, Chen H, Qin GQ, Shen W | Environ Mol Mutagen |
| Induced pluripotent stem cells as a model for telomeric abnormalities in ICF type I syndrome. | Sagie S, Ellran E, Katzir H, Shaked R, Yehezkel S, Laevsky I, Ghanayim A, Geiger D, Tzukerman M, Selig S | Hum Mol Genet |
| Continuous cadmium exposure from weaning to maturity induces downregulation of ovarian follicle development-related SCF/c-kit gene expression and the corresponding changes of DNA methylation/microRNA pattern. | Weng S, Wang W, Li Y, Li H, Lu X, Xiao S, Wu T, Xie M, Zhang W | Toxicol Lett |
| How to Analyze DNA Methylation? | Chmelarova, M. et. al. | Journal of Turgut Ozal Medical Center. |
| Unstable expression of transgene is associated with the methylation of CAG promoter in the offspring from the same litter of homozygous transgenic mice. | Zhou Y, Zhang T, Zhang QK, Jiang Y, Xu DG, Zhang M, Shen W, Pan QJ | Mol Biol Rep |
| Impaired methylation modifications of FZD3 alter chromatin accessibility and are involved in congenital hydrocephalus pathogenesis. | Wang L, Shangguan S, Chang S, Wang Z, Lu X, Wu L, Li R, Bao Y, Qiu Z, Niu B, Zhang T | Brain Res |
| Epigenetic modification of the leptin promoter in diet-induced obese mice and the effects of N-3 polyunsaturated fatty acids. | Shen W, Wang C, Xia L, Fan C, Dong H, Deckelbaum RJ, Qi K | Sci Rep |
| Aberrant Epigenetic Alteration in Eca9706 Cells Modulated by Nanoliposomal Quercetin Combined with Butyrate Mediated via Epigenetic-NF-κB Signaling. | Zheng NG, Wang JL, Yang SL, Wu JL | Asian Pac J Cancer Prev |
| Down-regulation of thyroid hormone receptor β1 gene expression in gastric cancer involves promoter methylation. | Ling Y, Shi X, Wang Y, Ling X, Li Q | Biochem Biophys Res Commun |
| Directed Differentiation of Patient-Specific Induced Pluripotent Stem Cells Identifies the Transcriptional Repression and Epigenetic Modification of NKX2-5, HAND1, and NOTCH1 in Hypoplastic Left Heart Syndrome. | Kobayashi J, Yoshida M, Tarui S, Hirata M, Nagai Y, Kasahara S, Naruse K, Ito H, Sano S, Oh H | PLoS One |
| CpG methylation of dmrt1 and cyp19a promoters in relation to their sexual dimorphic expression in the Japanese flounder Paralichthys olivaceus. | Wen AY, You F, Sun P, Li J, Xu DD, Wu ZH, Ma DY, Zhang PJ | J Fish Biol |
| Epigenetic alterations are involved in the overexpression of glutathione S-transferase π-1 in human colorectal cancers. | Zhang R, Kang KA, Piao MJ, Kim KC, Zheng J, Yao CW, Cha JW, Maeng YH, Chang WY, Moon PG, Baek MC, Hyun JW | Int J Oncol |
| GENOME-WIDE SCREEN OF PROMOTER METHYLATION IDENTIFIES NOVEL MARKERS IN DIET-INDUCED OBESE MICE. | Fan C, Dong H, Yan K, Shen W, Wang C, Xia L, Zhan D, Qi K | Nutr Hosp |
| The Effects of Lycopene on the Methylation of the GSTP1 Promoter and Global Methylation in Prostatic Cancer Cell Lines PC3 and LNCaP. | Fu LJ, Ding YB, Wu LX, Wen CJ, Qu Q, Zhang X, Zhou HH | Int J Endocrinol |
| Different Epigenetic Alterations Are Associated with Abnormal IGF2/Igf2 Upregulation in Neural Tube Defects. | Bai B, Zhang Q, Liu X, Miao C, Shangguan S, Bao Y, Guo J, Wang L, Zhang T, Li H | PLoS One |
| A simple, low-cost, and rapid device for a DNA methylation-specific amplification/detection system using a flexible plastic and silicon complex. | Lee TY, Shin Y, Park MK | Lab Chip |
| Methylation status of HPV16 E2-binding sites classifies subtypes of HPV-associated oropharyngeal cancers. | Reuschenbach M, Huebbers CU, Prigge ES, Bermejo JL, Kalteis MS, Preuss SF, Seuthe IM, Kolligs J, Speel EJ, Olthof N, Kremer B, Wagner S, Klussmann JP, Vinokurova S, von Knebel Doeberitz M | Cancer |
| The fused in sarcoma protein forms cytoplasmic aggregates in motor neurons derived from integration-free induced pluripotent stem cells generated from a patient with familial amyotrophic lateral sclerosis carrying the FUS-P525L mutation. | Liu X, Chen J, Liu W, Li X, Chen Q, Liu T, Gao S, Deng M | Neurogenetics |
| PTPRD is Homozygously Deleted and Epigenetically Downregulated in Human Hepatocellular Carcinomas. | Acun T, Demir K, Oztas E, Arango D, Yakicier MC | OMICS |
| Quantitative and multiplexed DNA methylation analysis using long-read single-molecule real-time bisulfite sequencing (SMRT-BS). | Yang Y, Sebra R, Pullman BS, Qiao W, Peter I, Desnick RJ, Geyer CR, DeCoteau JF, Scott SA | BMC Genomics |
| Differentiation of multipotent neural stem cells derived from Rett syndrome patients is biased toward the astrocytic lineage. | Andoh-Noda T, Akamatsu W, Miyake K, Matsumoto T, Yamaguchi R, Sanosaka T, Okada Y, Kobayashi T, Ohyama M, Nakashima K, Kurosawa H, Kubota T, Okano H | Mol Brain |
| 5-Azacitidine induces demethylation of PTPL1 and inhibits growth in non-Hodgkin lymphoma. | Wang W, Wang J, Li M, Ying J, Jing H | Int J Mol Med |
| Paxillin-dependent regulation of IGF2/H19 gene cluster expression. | Marášek P, Dzijak R, Studenyak I, FiÅ¡erová J, UliÄná L, Novák P, Hozák P | J Cell Sci |
| Laser capture microdissection as a tool to evaluate human papillomavirus genotyping and methylation as biomarkers of persistence and progression of anal lesions | Cornall AM, Roberts JM, Molano M, Machalek DA, Phillips S, Hillman RJ, Grulich AE, Jin F, Poynten IM, Templeton DJ, Garland SM | BMJ Open |
| Inhibition of Nuclear Receptor Binding SET Domain 2/Multiple Myeloma SET Domain by LEM-06 Implication for Epigenetic Cancer Therapies | Luccio E | J Cancer Prev |
| DNA methylation level of promoter region of activating transcription factor 5 in glioma. | Hua XM, Wang J, Qian DM, Song JY, Chen H, Zhu XL, Zhou R, Zhao YD, Zhou XZ, Li L, Zhang L, Song XX, Wang B | J Zhejiang Univ Sci B |
| Nicotine elevates sperm motility and induces Pfn1 promoter hypomethylation in mouse testis. | Dai J, Zhan C, Xu W, Wang Z, Nie D, Zhao X, Zhang D, Gu Y, Wang L, Chen Z, Qiao Z | Andrology |
| Genetic polymorphisms and DNA methylation in exon 1 CpG-rich regions of PACAP gene and its effect on mRNA expression and growth traits in half smooth tongue sole (Cynoglossus semilaevis). | Si Y, He F, Wen H, Li J, Zhao J, Ren Y, Zhao M, Ji L, Huang Z, Zhang M, Chen S | Fish Physiol Biochem |
| DNA methylation level of cyp19a1a and Foxl2 gene related to their expression patterns and reproduction traits during ovary development stages of Japanese flounder (Paralichthys olivaceus). | Si Y, Ding Y, He F, Wen H, Li J, Zhao J, Huang Z | Gene |
| Polymorphisms and DNA methylation level in the CpG site of the GHR1 gene associated with mRNA expression, growth traits and hormone level of half-smooth tongue sole (Cynoglossus semilaevis). | Zhao JL, Si YF, He F, Wen HS, Li JF, Ren YY, Zhao ML, Huang ZJ, Chen SL | Fish Physiol Biochem |
| Silver nanoparticles cause complications in pregnant mice. | Zhang XF, Park JH, Choi YJ, Kang MH, Gurunathan S, Kim JH | Int J Nanomedicine |
| Nicotine Induced Murine Spermatozoa Apoptosis via Up-Regulation of Deubiquitinated RIP1 by Trim27 Promoter Hypomethylation. | Nie D, Zhang D, Dai J, Zhang M, Zhao X, Xu W, Chen Z, Wang L, Wang Z, Qiao Z | Biol Reprod |
| Type 1 serrated polyposis represents a predominantly female disease with a high prevalence of dysplastic serrated adenomas, without germline mutation in MUTYH, APC, and PTEN genes | Petronio M, Stephane Pinson, Thomas Walter, Marie-Odile Joly, Valerie Hervieu, Julien Forestier, Jean-Christophe Saurin | United European Gastroenterol J |
| Protein profile screening: reduced expression of Sord in the mouse epididymis induced by nicotine inhibits tyrosine phosphorylation level in capacitated spermatozoa. | Dai J, Xu W, Zhao X, Zhang M, Zhang D, Nie D, Bao M, Wang Z, Wang L, Qiao Z | Reproduction |
| Aberrant expression of the candidate tumor suppressor gene DAL-1 due to hypermethylation in gastric cancer. | Wang H, Xu M, Cui X, Liu Y, Zhang Y, Sui Y, Wang D, Peng L, Wang D, Yu J | Sci Rep |
| Nicotine induces Nme2-mediated apoptosis in mouse testes. | Gu Y, Xu W, Nie D, Zhang D, Dai J, Zhao X, Zhang M, Wang Z, Chen Z, Qiao Z | Biochem Biophys Res Commun |
| Improved age determination of blood and teeth samples using a selected set of DNA methylation markers. | Bekaert B, Kamalandua A, Zapico SC, Van de Voorde W, Decorte R | Epigenetics |
| Nm23-H1 was involved in regulation of KAI1 expression in high-metastatic lung cancer cells L9981. | You J, Chang R, Liu B, Zu L, Zhou Q | J Thorac Dis |
| Methylation status of the promoter region of the human frizzled 9 gene in acute myeloid leukemia. | Zhang Y, Jiang Q, Kong X, Yang L, Hu W, Lv C, Li Y | Mol Med Rep |
| Reconstitution in vitro of the entire cycle of the mouse female germ line. | Hikabe O, Hamazaki N, Nagamatsu G, Obata Y, Hirao Y, Hamada N, Shimamoto S, Imamura T, Nakashima K, Saitou M, Hayashi K | Nature |
| CpG Methylation Analysis of HPV16 in Laser Capture Microdissected Archival Tissue and Whole Tissue Sections from High Grade Anal Squamous Intraepithelial Lesions: A Potential Disease Biomarker. | Molano M, Tabrizi SN, Garland SM, Roberts JM, Machalek DA, Phillips S, Chandler D, Hillman RJ, Grulich AE, Jin F, Poynten IM, Templeton DJ, Cornall AM | PLoS One |
| DNA methylation status of MyoD and IGF-I gene correlated with its muscle growth during different development stages of Japanese flounder (Paralichthys olivaceus). | Huang Y, Wen H, Zhang M, Hu N, Si Y, Li S, He F | Comp Biochem Physiol B Biochem Mol Biol |
| Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module. | Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, Shang M, Qiao Z | Sci Rep |
| Manipulation of Promoter-Associated Noncoding RNAs in Mouse Early Embryos for Controlling Sequence-Specific Epigenetic Status. | Hamazaki N, Nakashima K, Imamura T | Methods Mol Biol |
| A phase 2 study of temozolomide in pretreated metastatic colorectal cancer with MGMT promoter methylation. | Calegari MA, Inno A, Monterisi S, Orlandi A, Santini D, Basso M, Cassano A, Martini M, Cenci T, de Pascalis I, Camarda F, Barbaro B, Larocca LM, Gori S, Tonini G, Barone C | Br J Cancer |
| iPS Cell Cultures from a Gerstmann-Sträussler-Scheinker Patient with the Y218N PRNP Mutation Recapitulate tau Pathology. | Matamoros-Angles A, Gayosso LM, Richaud-Patin Y, di Domenico A, Vergara C, Hervera A, Sousa A, Fernández-Borges N, Consiglio A, GavÃn R, López de Maturana R, Ferrer I, López de Munain A, Raya Ã, Castilla J, Sánchez-Pernaute R, Del RÃo JA | Mol Neurobiol |
| HLJ1 (DNAJB4) Gene Is a Novel Biomarker Candidate in Breast Cancer. | Acun T, Doberstein N, Habermann JK, Gemoll T, Thorns C, Oztas E, Ried T | OMICS |
| Folate deficiency disturbs hsa-let-7 g level through methylation regulation in neural tube defects. | Wang L, Shangguan S, Xin Y, Chang S, Wang Z, Lu X, Wu L, Niu B, Zhang T | J Cell Mol Med |
| Paternal nicotine exposure defines different behavior in subsequent generation via hyper-methylation of mmu-miR-15b | Jingbo Dai et. al. | Scienti |
| CpG demethylation in the neurotoxicity of 1-methyl-4-phenylpyridinium might mediate transcriptional up-regulation of α-synuclein in SH-SY5Y cells. | Yang J, Yang Z, Wang X, Sun M, Wang Y, Wang X | Neurosci Lett |
| Non-random length distribution of individual telomeres in Immunodeficiency, Centromeric Instability and Facial anomalies syndrome, type I | Shira Sagie, Omer Edni, Joseph Weinber, Shir Toubiana, Tal Kozlovski, Tzviel Frostig, Nirit Katzin, Irit Bar-Am, Sara Selig | Oxford Academic |
| Continuous soy isoflavones exposure from weaning to maturity induces downregulation of ovarian steroidogenic factor 1 gene expression and corresponding changes in DNA methylation pattern. | Wang W, Sun Y, Guo Y, Cai P, Li Y, Liu J, Cai G, Kiyoshi A, Zhang W | Toxicol Lett |
| DNA Methylation Profiling Using Long-Read Single Molecule Real-Time Bisulfite Sequencing (SMRT-BS). | Yang Y, Scott SA | Methods Mol Biol |
| Analyzing epigenetic control of galectin expression indicates silencing of galectin-12 by promoter methylation in colorectal cancer. | Katzenmaier EM, Kloor M, Gabius HJ, Gebert J, Kopitz J | IUBMB Life |
| Alleviative effects of fluoxetine on depressive-like behaviors by epigenetic regulation of BDNF gene transcription in mouse model of post-stroke depression. | Jin HJ, Pei L, Li YN, Zheng H, Yang S, Wan Y, Mao L, Xia YP, He QW, Li M, Yue ZY, Hu B | Sci Rep |
| DNA methylation and expression of imprinted genes are associated with the viability of different sexual cloned buffaloes. | Ruan Z, Zhao X, Qin X, Luo C, Liu X, Deng Y, Zhu P, Li Z, Huang B, Shi D, Lu F | Reprod Domest Anim |
| Characteristics of induced pluripotent stem cells from clinically divergent female monozygotic twins with Danon disease. | Yoshida S, Nakanishi C, Okada H, Mori M, Yokawa J, Yoshimuta T, Ohta K, Konno T, Fujino N, Kawashiri MA, Yachie A, Yamagishi M, Hayashi K | J Mol Cell Cardiol |
| Laser Microdissection for Human Papillomavirus (HPV) Genotyping Attribution and Methylation Pattern Analyses of Squamous Intraepithelial Lesions. | Molano M, Garland SM, Cornall AM | Methods Mol Biol |
| Probiotic lactobacilli mediated changes in global epigenetic signatures of human intestinal epithelial cells during Escherichia coli challenge | Bhat, M.I., Kumari, A., Kapila, S. et al. | Annals of Microbiology |
| Methylation-mediated miR-155-FAM133A axis contributes to the attenuated invasion and migration of IDH mutant gliomas. | Huang GH, Du L, Li N, Zhang Y, Xiang Y, Tang JH, Xia S, Zhang EE, Lv SQ | Cancer Lett |
| DNA methylation levels and expression patterns of Smyd1a and Smyd1b genes during Metamorphosis of the Japanese Flounder (Paralichthys olivaceus). | Wu S, Huang Y, Li S, Wen H, Zhang M, Li J, Li Y, Shao C, He F | Comp Biochem Physiol B Biochem Mol Biol |
| Effects of SCFA on the DNA methylation pattern of adiponectin and resistin in high-fat-diet-induced obese male mice. | Lu Y, Fan C, Liang A, Fan X, Wang R, Li P, Qi K | Br J Nutr |
| Subtelomeric methylation distinguishes between subtypes of Immunodeficiency, Centromeric Instability and Facial Anomalies (ICF) syndrome. | Toubiana S, Velasco G, Chityat A, Kaindl AM, Hershtig N, Tzur-Gilat A, Francastel C, Selig S | Hum Mol Genet |
| Loss-of-function mutations in ATP6AP1 and ATP6AP2 in granular cell tumors. | Pareja F, Brandes AH, Basili T, Selenica P, Geyer FC, Fan D, Da Cruz Paula A, Kumar R, Brown DN, Gularte-Mérida R, Alemar B, Bi R, Lim RS, de Bruijn I, Fujisawa S, Gardner R, Feng E, Li A, da Silva EM, Lozada JR, Blecua P, Cohen-Gould L, Jungbluth AA, Rakha EA, Ellis IO, Edelweiss MIA, Palazzo J, Norton L, Hollmann T, Edelweiss M, | Nat Commun |
| Fresh red raspberry phytochemicals suppress the growth of hepatocellular carcinoma cells by PTEN/AKT pathway. | Zhang H, Liu J, Li G, Wei J, Chen H, Zhang C, Zhao J, Wang Y, Dang S, Li X, Fang X, Liu L, Liu M | Int J Biochem Cell Biol |
| In Utero Heat Stress Alters the Offspring Epigenome. | Skibiel AL, Peñagaricano F, AmorÃn R, Ahmed BM, Dahl GE, Laporta J | Sci Rep |
| [Methylation of the Reelin Gene Promoter in Peripheral Blood and Its Relationship with the Cognitive Function of Schizophrenia Patients]. | Alfimova MV, Kondratiev NV, Golov AK, Golimbet VE | Mol Biol (Mosk) |
| Prediction of smoking by multiplex bisulfite PCR with long amplicons considering allele-specific effects on DNA methylation. | Kondratyev N, Golov A, Alfimova M, Lezheiko T, Golimbet V | Clin Epigenetics |
| Long non-coding RNA FENDRR inhibits proliferation and invasion of hepatocellular carcinoma by down-regulating glypican-3 expression. | Wang B, Xian J, Zang J, Xiao L, Li Y, Sha M, Shen M | Biochem Biophys Res Commun |
| Relationship between Alzheimer's disease-associated SNPs within the CLU gene, local DNA methylation and episodic verbal memory in healthy and schizophrenia subjects. | Alfimova M, Kondratyev N, Golov A, Golimbet V | Psychiatry Res |
| The effect of folic acid deficiency on FGF pathway via Brachyury regulation in neural tube defects. | Chang S, Lu X, Wang S, Wang Z, Huo J, Huang J, Shangguan S, Li S, Zou J, Bao Y, Guo J, Wang F, Niu B, Zhang T, Qiu Z, Wu J, Wang L | FASEB J |
| Methionine Supply During Late-Gestation Triggers Offspring Sex-Specific Divergent Changes in Metabolic and Epigenetic Signatures in Bovine Placenta. | Batistel F, Alharthi AS, Yambao RRC, Elolimy AA, Pan YX, Parys C, Loor JJ | J Nutr |
| Derivation of Mouse Haploid Trophoblast Stem Cells. | Cui T, Jiang L, Li T, Teng F, Feng G, Wang X, He Z, Guo L, Xu K, Mao Y, Wang L, Yuan X, Wang L, Li W, Zhou Q | Cell Rep |
| FTSJ3 is an RNA 2′-O-methyltransferase recruited by HIV to avoid innate immune sensing | Ringeard M. et al. | Nature |
| Methylation of HIF3A promoter CpG islands contributes to insulin resistance in gestational diabetes mellitus. | Zhang Y, Chen Y, Qu H, Wang Y | Mol Genet Genomic Med |
| Methylation status and expression patterns of myomaker gene play important roles in postnatal development in the Japanese flounder (Paralichthys olivaceus). | Huang Y, Wu S, Zhang J, Wen H, Zhang M, He F | Gen Comp Endocrinol |
| Differentiation of primordial germ cells from premature ovarian insufficiency-derived induced pluripotent stem cells. | Yang S, Ding S, He S, He L, Gao K, Peng S, Shuai C | Stem Cell Res Ther |
| DNA methylation of miR-93: an important event in acquiring drug resistance in breast cancer cells | Hu J, Yi T, Chu S et. al. | Int J Clin Exp Med |
| A high methyl donor diet affects physiology and behavior in Peromyscus polionotus. | Yadon N, Owen A, Cakora P, Bustamante A, Hall-South A, Smith N, Felder MR, Vrana PB, Shorter KR | Physiol Behav |
| New aspects of dental implants and DNA technology in human identification | Mansour H et. al | FSI |
| Conditions of embryo culture from days 5 to 7 of development alter the DNA methylome of the bovine fetus at day 86 of gestation. | Li Y, TrÃbulo P, Bakhtiarizadeh MR, Siqueira LG, Ji T, Rivera RM, Hansen PJ | J Assist Reprod Genet |
| Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction. | Toubiana S, Gagliardi M, Papa M, Manco R, Tzukerman M, Matarazzo MR, Selig S | Elife |
| Paternal nicotine exposure induces hyperactivity in next-generation via down-regulating the expression of DAT. | Zhang M, Zhang D, Dai J, Cao Y, Xu W, He G, Wang Z, Wang L, Li R, Qiao Z | Toxicology |
| Pervasive promoter hypermethylation of silenced TERT alleles in human cancers | Esopi D et. al. | bioRxiv |
| Obesity-induced reduced expression of the lncRNA ROIT impairs insulin transcription by downregulation of Nkx6.1 methylation. | Zhang FF, Liu YH, Wang DW, Liu TS, Yang Y, Guo JM, Pan Y, Zhang YF, Du H, Li L, Jin L | Diabetologia |
| Profiling haplotype specific CpG and CpH methylation within a schizophrenia GWAS locus on chromosome 14 in schizophrenia and healthy subjects. | Alfimova M, Kondratyev N, Golov A, Golimbet V | Sci Rep |
| Loss of Thymine DNA Glycosylase Causes Dysregulation of Bile Acid Homeostasis and Hepatocellular Carcinoma. | Hassan HM, Isovic M, Kolendowski B, Bauer-Maison N, Onabote O, Cecchini M, Haig A, Maleki Vareki S, Underhill TM, Torchia J | Cell Rep |
| Parkinson's disease therapy with Istradefylline and blood biomarkers of epigenetics | Kanzato, N et. al. | NCN |
| Alteration of gut microbiota affects expression of adiponectin and resistin through modifying DNA methylation in high-fat diet-induced obese mice. | Yao H, Fan C, Lu Y, Fan X, Xia L, Li P, Wang R, Tang T, Wang Y, Qi K | Genes Nutr |
| Transient Dux expression facilitates nuclear transfer and induced pluripotent stem cell reprogramming. | Yang L, Liu X, Song L, Di A, Su G, Bai C, Wei Z, Li G | EMBO Rep |
| Association between prenatal bisphenol a exposure and promoter hypermethylation of CAPS2, TNFRSF25, and HKR1 genes in cord blood. | Song X, Zhou X, Yang F, Liang H, Wang Z, Li R, Miao M, Yuan W | Environ Res |
| Regulation of telomeric function by DNA methylation differs between humans and mice. | Toubiana S, Larom G, Smoom R, Duszynski RJ, Godley LA, Francastel C, Velasco G, Selig S | Hum Mol Genet |
| TET2 directs mammary luminal cell differentiation and endocrine response. | Kim MR, Wu MJ, Zhang Y, Yang JY, Chang CJ | Nat Commun |
| Gene duplication, rather than epigenetic changes, drives FGF4 overexpression in KIT/PDGFRA/SDH/RAS-P WT GIST. | Urbini M, Astolfi A, Indio V, Nannini M, Schipani A, Bacalini MG, Angelini S, Ravegnini G, Calice G, Del Gaudio M, Secchiero P, Ulivi P, Gruppioni E, Pantaleo MA | Sci Rep |
| Altered DNA methylation in a severe subtype of idiopathic autism: Evidence for sex differences in affected metabolic pathways. | Hu VW, Hong Y, Xu M, Shu HT | Autism |
| Unexplored regulatory sequences of divergently paired GLA and HNRNPH2 loci pertinent to Fabry disease in human kidney and skin cells: Presence of an active bidirectional promoter | Ibrahim Al-Obaide M. et.al. | Experimental and Therapeutic Medicine |
| A methylation signature at the CpG island promoter of estrogen receptor beta (ER-β) in breasts of women may be an early footmark of lack of breastfeeding and nulliparity. | Daraei A, Izadi P, Khorasani G, Nafissi N, Naghizadeh MM, Meysamie A, Mansoori Y, Nariman-Saleh-Fam Z, Bastami M, Saadatian Z, Roshan SJ, Bayani N, Tavakkoly-Bazzaz J | Pathol Res Pract |
| Maternal high-fat-diet exposure is associated with elevated blood pressure and sustained increased leptin levels through epigenetic memory in offspring. | Lin XH, Gao L, Tian S, Klausen C, Guo MX, Gao Q, Liu ME, Wang H, Wu DD, Zhou CL, Yang J, Meng Y, Liu Y, Xu GF, Tan YJ, Ullah K, Zhu YM, Fraser WD, Sheng JZ, Leung PCK, Muglia LJ, Wu YT, Huang HF | Sci Rep |
| Expression and DNA Methylation Status of the Imprinted Genes PEG10 and L3MBTL1 in the Umbilical Cord Blood and Placenta of the Offspring of Assisted Reproductive Technology. | Wang YX, Yue LF, Zhang JW, Xiong YW, Hu JJ, Wang LL, Li Z, Liu Y, Yang L, Sun LJ | Reprod Sci |
| Ascorbic Acid: A New Player of Epigenetic Regulation in LPS-<i>gingivalis</i> Treated Human Periodontal Ligament Stem Cells. | Marconi GD, Fonticoli L, Guarnieri S, Cavalcanti MFXB, Franchi S, Gatta V, Trubiani O, Pizzicannella J, Diomede F | Oxid Med Cell Longev |
| Circulating Cell-Free DNA Methylation Profiles in the Early Detection of Ovarian Cancer: A Scoping Review of the Literature. | Guo XM, Miller H, Matsuo K, Roman LD, Salhia B | Cancers (Basel) |
| Unique adaptations in neonatal hepatic transcriptome, nutrient signaling, and one-carbon metabolism in response to feeding ethyl cellulose rumen-protected methionine during late-gestation in Holstein cows. | Palombo V, Alharthi A, Batistel F, Parys C, Guyader J, Trevisi E, D'Andrea M, Loor JJ | BMC Genomics |
| Homocysteine restrains hippocampal neurogenesis in focal ischemic rat brain by inhibiting DNA methylation. | Gou Y, Ye Q, Liang X, Zhang Q, Luo S, Liu H, Wang X, Sai N, Zhang X | Neurochem Int |
| Two Small Molecule Inhibitors Promote Reprogramming of Guangxi Bama Mini-Pig Mesenchymal Stem Cells Into Naive-Like State Induced Pluripotent Stem Cells. | Chen F, Shi D, Zou L, Yang X, Qiao S, Zhang R, Yang S, Deng Y | Cell Reprogram |
| RBL2 bi-allelic truncating variants cause severe motor and cognitive impairment without evidence for abnormalities in DNA methylation or telomeric function. | Samra N, Toubiana S, Yttervik H, Tzur-Gilat A, Morani I, Itzkovich C, Giladi L, Abu Jabal K, Cao JZ, Godley LA, Mory A, Baris Feldman H, Tveten K, Selig S, Weiss K | J Hum Genet |
| Epigenetic Characteristics of Human Subtelomeres Vary in Cells Utilizing the Alternative Lengthening of Telomeres (ALT) Pathway. | Toubiana S, Tzur-Gilat A, Selig S | Life (Basel) |
| Heat stress and immune response phenotype affect DNA methylation in blood mononuclear cells from Holstein dairy cows. | Livernois AM, Mallard BA, Cartwright SL, Cánovas A | Sci Rep |
| The miR-455-3p/HDAC2 axis plays a pivotal role in the progression and reversal of liver fibrosis and is regulated by epigenetics. | You H, Wang L, Bu F, Meng H, Pan X, Li J, Zhang Y, Wang A, Yin N, Huang C, Li J | FASEB J |
| PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis | Li, X.F., et. al. | Front. Pharmacol. |
| Unexplored regulatory sequences of divergently paired <i>GLA</i> and <i>HNRNPH2</i> loci pertinent to Fabry disease in human kidney and skin cells: Presence of an active bidirectional promoter. | Al-Obaide MAI, Al-Obaidi II, Vasylyeva TL | Exp Ther Med |
| PTEN Methylation Promotes Inflammation and Activation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis | Li XF, Wu S, Yan Q, Wu YY, Chen H, Yin SQ, Chen X, Wang H, Li J | Front Pharmacol |
| SoxE group transcription factor Sox8 promotes astrocytic differentiation of neural stem/precursor cells downstream of Nfia. | Takouda J, Katada S, Imamura T, Sanosaka T, Nakashima K | Pharmacol Res Perspect |
| N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination. | Marechal D, Dansu DK, Castro K, Patzig J, Magri L, Inbar B, Gacias M, Moyon S, Casaccia P | Glia |
| Prevention of Inorganic Arsenic induced Squamous Cell Carcinoma of Skin in Swiss Albino Mice By Black Tea Through Epigenetic Modulation | Ghosh, A., et. al. | Research Square |
| Prenatal exposure to polycyclic aromatic hydrocarbons could increase the risk of low birth weight by affecting the DNA methylation states in a Chinese cohort. | Cao C, Jia Z, Shao M, Li R, Sun Q, Liu D | Reprod Biol |
| Effect of epigenetic activating of Dlk1-Dio3 imprinted cluster on miR-370 expression due to folate deficiency during nerve development | Chang, S. et. al. | J Nutr Biochem |
| Profiling Genome-Wide DNA Methylation Patterns in Human Aortic and Mitral Valves. | Halawa S, Latif N, Tseng YT, Ibrahim AM, Chester AH, Moustafa A, Aguib Y, Yacoub MH | Front Cardiovasc Med |
| Reciprocal SOX2 regulation by SMAD1-SMAD3 is critical for anoikis resistance and metastasis in cancer. | Shonibare Z, Monavarian M, O'Connell K, Altomare D, Shelton A, Mehta S, Jaskula-Sztul R, Phaeton R, Starr MD, Whitaker R, Berchuck A, Nixon AB, Arend RC, Lee NY, Miller CR, Hempel N, Mythreye K | Cell Rep |
| Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension. | Jacob C, Kitagawa A, Signoretti C, Dzieciatkowska M, D'Alessandro A, Gupte A, Hossain S, D'Addario CA, Gupte R, Gupte SA | J Biol Chem |
| DNA methylation and expression of the egfr gene are associated with worker size in monomorphic ants. | Renard T, Gueydan C, Aron S | Sci Rep |
| Multigenerational genetic effects of paternal cadmium exposure on ovarian granulosa cell apoptosis. | Sun Y, Zhang W, Li Y, Zhu J, Liu C, Luo L, Liu J, Zhang C | Ecotoxicol Environ Saf |
| Chemoprevention of lotus leaf ethanolic extract through epigenetic activation of the NRF2-mediated pathway in murine skin JB6 P+ cell neoplastic transformation. | Tung YC, Sung PH, Chen PC, Wang HC, Lee JH, Su ZY | J Tradit Complement Med |
| Aromatic Hydrocarbon Receptor Repressor (AHRR) Is a Biomarker of Ambient Air Pollution Exposure and Coronary Artery Disease (CAD). | Ridany I, Akika R, Saliba NA, Tamim H, Badr K, Zgheib NK | Environ Toxicol Pharmacol |
| Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program. | Shorey-Kendrick LE, Davis B, Gao L, Park B, Vu A, Morris CD, Breton CV, Fry R, Garcia E, Schmidt RJ, O'Shea TM, Tepper RS, McEvoy CT, Spindel ER | Environ Health Perspect |
| Development and Validation of a Novel Placental DNA Methylation Biomarker of Maternal Smoking during Pregnancy in the ECHO Program. | Shorey-Kendrick LE, Davis B, Gao L, Park B, Vu A, Morris CD, Breton CV, Fry R, Garcia E, Schmidt RJ, O'Shea TM, Tepper RS, McEvoy CT, Spindel ER | Environ Health Perspect |
| KDM1A, a potent and selective target, for the treatment of DNMT3A-deficient non-small cell lung cancer. | Zhao Y, Zheng Y, Fu J, Zhang J, Shao H, Liu S, Lai J, Zhou X, Liang R, Jia L, Cui W, Yang J, Wu C, Wang L | Br J Cancer |
| DNA methylation at individual CpG-sites of EPB41L3, HTERT and FAM19A4 are useful for detection of cervical high-grade squamous intraepithelial lesions (HSIL) or worse: Analysis of individual CpG-sites outperforms averaging. | Molano M, Machalek DA, Phillips S, Tan G, Garland SM, Hawkes D, Balgovind P, Haqshenas R, Badman SG, Bolnga J, Gabuzzi J, Kombati Z, Munnull GM, Brotherton JM, Saville M, Kaldor JM, Toliman PJ, Vallely AJ, Murray GL | Tumour Virus Res |
| Epigenomic Alterations of the Human CYP11B Gene in Adrenal Zonation. | Takeda Y, Demura M, Yoneda T, Karashima S, Kometani M, Aono D, Konishi S, Horike SI, Nakamura Y, Yamazaki Y, Sasano H, Takeda Y | Int J Mol Sci |
| Late gestation heat stress alters placental structure and function in multiparous dairy cows. | Casarotto LT, Jones HN, Chavatte-Palmer P, Laporta J, Peñagaricano F, Ouellet V, Bromfield J, Dahl GE | J Dairy Sci |
| Epigenetic Regulation of Nuclear Factor Erythroid-2-Related Factor 2 in Colorectal Cancer Cells Resistant to Ionizing Radiation. | Kang KA, Park J, Piao MJ, Fernando PDSM, Herath HMUL, Senavirathna HMMM, Kim JH, Cho SJ, Hyun JW | Biomol Ther (Seoul) |
