MethylFlash™ 整体 DNA 甲基化 （5-mC） ELISA 简易试剂盒是一整套优化的缓冲液和试剂，通过在简化的“一步法”类似 ELISA 反应中特异性测量 5-甲基胞嘧啶 （5-mC） 水平，以比色定量整体 DNA 甲基化状态。这使得直接测量整体 DNA 甲基化的速度比其他技术（如基于 LUMA、LINE-1、Alu 或 LTR 的检测）更快。作为 EpigenTek 专利全局 DNA 甲基化技术的第四代技术，它通过提高速度、简单性、灵敏度和可重复性，进一步改进了流行的前代 MethylFlash 试剂盒。
| 产品名称 | 货号 | 规格 |
| MethylFlash™ 整体 DNA 甲基化 （5-mC） ELISA 简易试剂盒
MethylFlash Global DNA Methylation (5-mC) ELISA Easy Kit (Colorimetric) |
P-1030 | 48次反应
96次反应 |
该试剂盒还经过专门优化，可与 MethylFlash Global DNA 羟甲基化 （5-hmC） ELISA Easy 试剂盒（比色法）配合使用，同时定量甲基化 DNA 和羟甲基化 DNA。
该MethylFlash Global DNA 羟甲基化 （5-hmC） ELISA Easy 试剂盒具有以下优点和特点：
- 快速 - 减少步骤，整个过程只需 2 小时
- 稳健 - 改进的试剂盒组成使分析具有更大的“信号窗口”，同时减少重复之间的变化
- 方便 - 固有的低背景噪音，因此无需 DNA 变性和板封闭步骤
- 灵敏 — 检测限可低至 100 ng 起始 DNA 中 0.05% 甲基化 DNA
- 特定-对 5 mC 具有高度特异性，在样品 DNA 的指定浓度范围内，与未甲基化的胞嘧啶无交叉反应性，与羟甲基胞嘧啶无交叉反应性
- 通用 — 包括阳性和阴性对照，可从单链或双链起始 DNA 中检测任何物种的 DNA 甲基化
- 准确-优化的阳性对照，可以百分比刻度进行分级，使分析更加准确，并与 HPLC-MS 分析具有高度可比性
- 灵活 - 条孔板规格使该分析可用于手动或高通量分析
已发表的文献：
| 标题 | 作者 | 杂志名称 |
| Placental superoxide dismutase 3 mediates benefits of maternal exercise on offspring health. | Kusuyama J, Alves-Wagner AB, Conlin RH, Makarewicz NS, Albertson BG, Prince NB, Kobayashi S, Kozuka C, Møller M, Bjerre M, Fuglsang J, Miele E, Middelbeek RJW, Xiudong Y, Xia Y, Garneau L, Bhattacharjee J, Aguer C, Patti ME, Hirshman MF, Jessen N, Hatta T, Ovesen PG, Adamo KB, Nozik-Grayck E, Goodyear LJ | Cell Metab |
| Examination of Global Methylation and Targeted Imprinted Genes in Prader- Willi Syndrome | AM Manzardo and MG Butler | Imedpub |
| Variable Methylation Potential in Preterm Placenta: Implication for Epigenetic Programming of the Offspring. | Khot VV, Chavan-Gautam P, Mehendale S, Joshi SR | Reprod Sci |
| Bisphenol A (BPA) in the serum of pet dogs following short-term consumption of canned dog food and potential health consequences of exposure to BPA. | Koestel ZL, Backus RC, Tsuruta K, Spollen WG, Johnson SA, Javurek AB, Ellersieck MR, Wiedmeyer CE, Kannan K, Xue J, Bivens NJ, Givan SA, Rosenfeld CS | Sci Total Environ |
| Isolation of an indigenous Chlorella vulgaris from swine wastewater and characterization of its nutrient removal ability in undiluted sewage | Yangmin Wen, Yongjin He, Xiaowei Ji, Shaofeng Li, Ling Chen, Youcai Zhou, Mingzi Wang, Bilian Chen | Bioresource Technology |
| DNA Methylation Analysis in Smokers and Non-Smokers (Passive and ex-Smokers) | Aguilar-Beltrán, D.M et. al. | Journal of Thoracic Oncology |
| Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis. | Maiuri AR, Peng M, Sriramkumar S, Kamplain CM, DeStefano Shields CE, Sears CL, O'Hagan HM | Cancer Res |
| Trichostatin A sensitizes hepatoma cells to Taxol more than 5-Aza-dC and dexamethasone. | Donia T, Khedr S, Salim EI, Hessien M | Drug Metab Pers Ther |
| Perinatal high fat diet and early life methyl donor supplementation alter one carbon metabolism and DNA methylation in the brain. | McKee SE, Zhang S, Chen L, Rabinowitz JD, Reyes TM | J Neurochem |
| Periconceptional Folic Acid Supplementation Benefit to Development of Early Sensory-Motor Function through Increase DNA Methylation in Rat Offspring. | Li W, Li Z, Li S, Wang X, Wilson JX, Huang G | Nutrients |
| SMYD2 promoter DNA methylation is associated with abdominal aortic aneurysm (AAA) and SMYD2 expression in vascular smooth muscle cells | Toghill BJ, Saratzis A, Freeman PJ, Sylvius N, Bown MJ | Clin Epigenetics |
| Withaferin A and Sulforaphane Regulate Breast Cancer Cell Cycle Progression through Epigenetic Mechanisms. | Royston KJ, Paul B, Nozell S, Rajbhandari R, Tollefsbol TO | Exp Cell Res |
| DNA methylation of the BRD2 promoter is associated with juvenile myoclonic epilepsy in Caucasians. | Pathak S, Miller J, Morris EC, Stewart WCL, Greenberg DA | Epilepsia |
| Folate modulates guanine-quadruplex frequency and DNA damage in Werner syndrome. | Tavakoli Shirazi P, Leifert WR, Fenech MF, François M | Mutat Res |
| Global and Complement Gene-Specific DNA Methylation in Grass Carp after Grass Carp Reovirus (GCRV) Infection. | Xiong L, He L, Luo L, Li Y, Liao L, Huang R, Zhu Z, Wang Y | Int J Mol Sci |
| Global Changes of 5-mC/5h-mC Ratio and Methylation of Adiponectin and Leptin Gene in Placenta Depending on Mode of Delivery. | Słabuszewska-Jóźwiak A, Malinowska M, Kloska A, Jakóbkiewicz-Banecka J, Gujski M, Bojar I, Raczkiewicz D, Jakiel G | Int J Mol Sci |
| Folate treatment of pregnant rat dams abolishes metabolic effects in female offspring induced by a paternal pre-conception unhealthy diet. | Li J, Lu YP, Tsuprykov O, Hasan AA, Reichetzeder C, Tian M, Zhang XL, Zhang Q, Sun GY, Guo J, Gaballa MMS, Peng XN, Lin G, Hocher B | Diabetologia |
| CRISPR/Cas9-mediated gene knockout for DNA methyltransferase Dnmt3a in CHO cells displays enhanced transgenic expression and long-term stability. | Jia YL, Guo X, Lu JT, Wang XY, Qiu LL, Wang TY | J Cell Mol Med |
| SNHG6 acts as a genome-wide hypomethylation trigger via coupling of miR-1297-mediated S-adenosylmethionine-dependent positive feedback loops. | Guo T, Wang H, Liu P, Xiao Y, Wu P, Wang Y, Chen B, Zhao Q, Liu Z, Liu Q | Cancer Res |
| Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. | Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH | J Biol Chem |
| Temporal efficacy of a sulforaphane-based broccoli sprout diet in prevention of breast cancer through modulation of epigenetic mechanisms. | Li Y, Buckhaults P, Li S, Tollefsbol TO | Cancer Prev Res (Phila) |
| EZH2 Methyltransferase Activity Controls Pten Expression and mTOR Signaling During Fear Memory Reconsolidation. | Jarome TJ, Perez GA, Hauser RM, Hatch KM, Lubin FD | J Neurosci |
| Folic acid modulates VPO1 DNA methylation levels and alleviates oxidative stress-induced apoptosis in vivo and in vitro | Cui S, Lv X,Li W, Li Z, Liu H, Gao Y, Huang G | Redox Biology |
| Effects of β-carotene on Expression of Selected MicroRNAs, Histone Acetylation, and DNA Methylation in Colon Cancer Stem Cells. | Kim D, Kim Y, Kim Y | J Cancer Prev |
| Cellular, transcriptomic and methylome effects of individual and combined exposure to BPA, BPF, BPS on mouse spermatocyte GC-2 cell line. | Sidorkiewicz I, Czerniecki J, Jarząbek K, Zbucka-Krętowska M, Wołczyński S | Toxicol Appl Pharmacol |
| Hypothalamic DNA methylation in rats with dihydrotestosterone-induced polycystic ovary syndrome: effects of low-frequency electro-acupuncture. | Cui P, Ma T, Tamadon A, Han S, Li B, Chen Z, An X, Shao LR, Wang Y, Feng Y | Exp Physiol |
| Multiplication of the SNCA locus exacerbates neuronal nuclear aging. | Tagliafierro L, Zamora ME, Chiba-Falek O | Hum Mol Genet |
| Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2. | Ye Y, Tang Y, Xiong Y, Feng L, Li X | FASEB J |
| Early-life epigenetic changes along the corticotropin-releasing hormone (CRH) gene influence resilience or vulnerability to heat stress later in life | Cramer T | Molecular Psychiatry |
| Effect of Jieduquyuziyin prescription-treated rat serum on MeCP2 gene expression in Jurkat T cells. | Li R, Zhuang A, Ma J, Ji L, Hou X, Chen H, Pan X, Liu W | In Vitro Cell Dev Biol Anim |
| The collaborative effect of Chlorella vulgaris-Bacillus licheniformis consortia on the treatment of municipal water. | Ji X, Li H, Zhang J, Saiyin H, Zheng Z | J Hazard Mater |
| Methods for Analysis of DNA Methylation | Sant K, Goodrich J | Toxicoepigenetics |
| Changes in DNA methylation and imprinting disorders in E9.5 mouse fetuses and placentas derived from vitrified 8-cell embryos. | Ma Y, Ma Y, Wen L, Lei H, Chen S, Wang X | Mol Reprod Dev |
| Intermediate-term memory in <i>Aplysia</i> involves neurotrophin signaling, transcription, and DNA methylation. | Yang Q, Antonov I, Castillejos D, Nagaraj A, Bostwick C, Kohn A, Moroz L, Hawkins RD | Learn Mem |
| Decreased Nuclear Ascorbate Accumulation Accompanied with Altered Genomic Methylation Pattern in Fibroblasts from Arterial Tortuosity Syndrome Patients | Nemeth C.E. et Al. | Oxidative Medicine and Cellular Longevity |
| PARP Inhibitor Affects Long-term Heat-stress Response via Changes in DNA Methylation. | Cramer T, Rosenberg T, Kisliouk T, Meiri N | Neuroscience |
| DNA Methylation Regulates Corneal Epithelial Wound Healing by Targeting miR-200a and CDKN2B. | Luo G, Jing X, Yang S, Peng D, Dong J, Li L, Reinach PS, Yan D | Invest Ophthalmol Vis Sci |
| Phytochemicals Rosmarinic Acid, Ampelopsin, and Amorfrutin-A Can Modulate Age-Related Phenotype of Serially Passaged Human Skin Fibroblasts <i>in vitro</i>. | Sodagam L, Lewinska A, Kwasniewicz E, Kokhanovska S, Wnuk M, Siems K, Rattan SIS | Front Genet |
| Dysregulated transmethylation leading to hepatocellular carcinoma compromises redox homeostasis and glucose formation. | Hughey CC, James FD, Wang Z, Goelzer M, Wasserman DH | Mol Metab |
| Multi-generational impacts of organic contaminated stream water on Daphnia magna: A combined proteomics, epigenetics and ecotoxicity approach. | Chatterjee N, Choi S, Kwon OK, Lee S, Choi J | Environ Pollut |
| Decreased Nuclear Ascorbate Accumulation Accompanied with Altered Genomic Methylation Pattern in Fibroblasts from Arterial Tortuosity Syndrome Patients. | Németh CE, Nemoda Z, Lőw P, Szabó P, Horváth EZ, Willaert A, Boel A, Callewaert BL, Coucke PJ, Colombi M, Bánhegyi G, Margittai É | Oxid Med Cell Longev |
| Seasonal DNA methylation variation in the flat tree oyster Isognomon alatus from a mangrove ecosystem in North Biscayne Bay, Florida | Suarez-Ulloa V., Rivera-Casas C., Michel M. and J. Eirin-Lopez | Journal of Shellfish Research |
| Genomic DNA methylation signatures in different tissues after ambient air particulate matter exposure. | Li Z, Li N, Guo C, Li X, Qian Y, Wu J, Yang Y, Wei Y | Ecotoxicol Environ Saf |
| Pleiotropic neuroprotective effects of taxifolin in cerebral amyloid angiopathy. | Inoue T, Saito S, Tanaka M, Yamakage H, Kusakabe T, Shimatsu A, Ihara M, Satoh-Asahara N | Proc Natl Acad Sci U S A |
| Body burdens of heavy metals associated with epigenetic damage in children living in the vicinity of a municipal waste incinerator. | Xu P, Chen Z, Chen Y, Feng L, Wu L, Xu D, Wang X, Lou X, Lou J | Chemosphere |
| Preventing epigenetic traces of caregiver maltreatment: A role for HDAC inhibition. | Doherty TS, Chajes JR, Reich L, Duffy HBD, Roth TL | Int J Dev Neurosci |
| Collagen prolyl hydroxylation-dependent metabolic perturbation governs epigenetic remodeling and mesenchymal transition in pluripotent and cancer cells. | D'Aniello C, Cermola F, Palamidessi A, Wanderlingh LG, Gagliardi M, Migliaccio A, Varrone F, Casalino L, Matarazzo MR, De Cesare D, Scita G, Patriarca EJ, Minchiotti G | Cancer Res |
| Genome-wide DNA methylation and hydroxymethylation analysis reveal human menstrual blood-derived stem cells inhibit hepatocellular carcinoma growth through oncogenic pathway suppression via regulating 5-hmC in enhancer elements. | Wu Y, Chen X, Zhao Y, Wang Y, Li Y, Xiang C | Stem Cell Res Ther |
| Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs. | Cornacchia D, Zhang C, Zimmer B, Chung SY, Fan Y, Soliman MA, Tchieu J, Chambers SM, Shah H, Paull D, Konrad C, Vincendeau M, Noggle SA, Manfredi G, Finley LWS, Cross JR, Betel D, Studer L | Cell Stem Cell |
| Hepatitis B virus X protein enhances hepatocarcinogenesis by depressing the targeting of NUSAP1 mRNA by miR-18b | Yang Z, Li J, Feng G et. al. | Cancer Biol Med |
| Periconceptional alcohol exposure causes female-specific perturbations to trophoblast differentiation and placental formation in the rat. | Kalisch-Smith JI, Steane SE, Simmons DG, Pantaleon M, Anderson ST, Akison LK, Wlodek ME, Moritz KM | Development |
| Age-related macular degeneration (AMD) mitochondria modulate epigenetic mechanisms in retinal pigment epithelial cells. | Nashine S, Nesburn AB, Kuppermann BD, Kenney MC | Exp Eye Res |
| Zika virus alters DNA methylation status of genes involved in Hippo signaling pathway in human neural progenitor cells. | Kandilya D, Maskomani S, Shyamasundar S, Tambyah PA, Shiao Yng C, Lee RCH, Hande MP, Mallilankaraman K, Chu JJH, Dheen ST | Epigenomics |
| Perfluorobutanesulfonate Exposure Skews Sex Ratio in Fish and Transgenerationally Impairs Reproduction. | Chen L, Lam JCW, Hu C, Tsui MMP, Lam PKS, Zhou B | Environ Sci Technol |
| All in One High Quality Genomic DNA and Total RNA Extraction From Nematode Induced Galls for High Throughput Sequencing Purposes. | Silva AC, Ruiz-Ferrer V, MartÃnez-Gómez Ã, Barcala M, Fenoll C, Escobar C | Front Plant Sci |
| Pharmacological manipulation of DNA methylation normalizes maternal behavior, DNA methylation, and gene expression in dams with a history of maltreatment. | Keller SM, Doherty TS, Roth TL | Sci Rep |
| Implication for DNA methylation involved in the host transfer of diamondback moth, Plutella xylostella (L.). | Chen W, Dong Y, Lin L, Saqib HSA, Ma X, Xu X, Zhang L, Jing X, Peng L, Wang Y, Vasseur L, He W, You M | Arch Insect Biochem Physiol |
| A 2x folic acid treatment affects epigenetics and dendritic spine densities in SHSY5Y cells. | Al Sayed R, Smith W, Rogers N, Smith N, Clark D, Castillo G, McLeod H, Glenister S, Shorter KR | Biochem Biophys Rep |
| Dynamic changes in DNA methylation during embryonic and postnatal development of an altricial wild bird | Watson H, Salmon P, Isaksson C | Ecology and Evolution |
| Dynamic changes in DNA methylation during embryonic and postnatal development of an altricial wild bird. | Watson H, Salmón P, Isaksson C | Ecol Evol |
| Resistance Training Modulates the Humoral Inflammatory (but Not the DNA Methylation) Profile of Diabetic Older Adults Using Metformin. | Morais Junior GS, Souza VC, Machado-Silva W, Henriques AD, Avelar GG, Perez DIV, Lima RM, Silva RJS, Brito CJ, Nóbrega OT | Neuroimmunomodulation |
| [Folic acid relieves rat cardiomyocyte injury induced by homocystein through DNA methylation]. | Hao Y, Li P, Yan N, Zhang Z | Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi |
| DNA methylation and behavioral changes induced by neonatal spinal transection. | Doherty TS, Bozeman AL, Roth TL, Brumley MR | Infant Behav Dev |
| Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. | Lombardi AA, Gibb AA, Arif E, Kolmetzky DW, Tomar D, Luongo TS, Jadiya P, Murray EK, Lorkiewicz PK, Hajnóczky G, Murphy E, Arany ZP, Kelly DP, Margulies KB, Hill BG, Elrod JW | Nat Commun |
| Elimination of human folypolyglutamate synthetase alters programming and plasticity of somatic cells. | Srivastava AC, Thompson YG, Singhal J, Stellern J, Srivastava A, Du J, O'Connor TR, Riggs AD | FASEB J |
| LncRNA RMST enhances DNMT3 expression through interaction with HuR | Peng W.X et. al | Molecular Therapy |
| Homocysteine accelerates atherosclerosis by inhibiting scavenger receptor class B member1 via DNMT3b/SP1 pathway. | Guo W, Zhang H, Yang A, Ma P, Sun L, Deng M, Mao C, Xiong J, Sun J, Wang N, Ma S, Nie L, Jiang Y | J Mol Cell Cardiol |
| A Novel Understanding of Global DNA Methylation in Bobcat (Lynx rufus). | Cantrell B, Friedman SR, Lachance H, Bernier C, Murdoch B, Frattini S, Talenti A, Crepaldi P, McKay S | Genome |
| Interleukin 1β and Prostaglandin E2 affect expression of DNA methylating and demethylating enzymes in human gingival fibroblasts. | Seutter S, Winfield J, Esbitt A, Snyder S, Magner A, Kim K, Carcuffe C, Schmoyer J, Kamrani P, Mercando J, Shamseddin SM, Green K, Borghaei RC | Int Immunopharmacol |
| Association of N<sup>6</sup>-methyladenine DNA with plaque progression in atherosclerosis via myocardial infarction-associated transcripts. | Wu L, Pei Y, Zhu Y, Jiang M, Wang C, Cui W, Zhang D | Cell Death Dis |
| African and Asian Mitochondrial DNA Haplogroups Confer Resistance Against Diabetic Stresses on Retinal Pigment Epithelial Cybrid Cells In Vitro. | Dolinko AH, Chwa M, Atilano SR, Kenney MC | Mol Neurobiol |
| Rescue of ethanol-induced FASD-like phenotypes via prenatal co-administration of choline. | Bottom RT, Abbott CW 3rd, Huffman KJ | Neuropharmacology |
| Phloroglucinol Treatment Induces Transgenerational Epigenetic Inherited Resistance Against <i>Vibrio</i> Infections and Thermal Stress in a Brine Shrimp (<i>Artemia franciscana</i>) Model. | Roy S, Kumar V, Bossier P, Norouzitallab P, Vanrompay D | Front Immunol |
| Life cycle exposure to propiconazole reduces fecundity by disrupting the steroidogenic pathway and altering DNA methylation in zebrafish (Danio rerio) | Teng, M et. al. | Environment International |
| Life cycle exposure to propiconazole reduces fecundity by disrupting the steroidogenic pathway and altering DNA methylation in zebrafish (Danio rerio). | Teng M, Chen X, Wang C, Song M, Zhang J, Bi S, Wang C | Environ Int |
| Oleic acid influences the adipogenesis of 3T3-L1 cells via DNA Methylation and may predispose to obesity and obesity-related disorders. | Malodobra-Mazur M, Cierzniak A, Dobosz T | Lipids Health Dis |
| Acute PFOA exposure promotes epigenomic alterations in mouse kidney tissues | Rashid F, et. al. | Toxicology Reports |
| Maternal Exposure to High-Fat Diet Induces Long-Term Derepressive Chromatin Marks in the Heart. | Blin G, Liand M, Mauduit C, Chehade H, Benahmed M, Simeoni U, Siddeek B | Nutrients |
| Accelerated cardiomyocyte senescence contributes to late-onset doxorubicin-induced cardiotoxicity. | Mitry MA, Laurent D, Keith BL, Sira E, Eisenberg CA, Eisenberg LM, Joshi S, Gupte S, Edwards JG | Am J Physiol Cell Physiol |
| Vitamin B12 is neuroprotective in experimental pneumococcal meningitis through modulation of hippocampal DNA methylation | de Queiroz K.B et al. | bioRxiv |
| Epigenetic toxicity of PFOA and GenX in HepG2 cells and their roles in lipid metabolism. | Wen Y, Mirji N, Irudayaraj J | Toxicol In Vitro |
| Inflammation-mediated generation and inflammatory potential of human placental cell-free fetal DNA | van Boeckel S.R et. al. | Placenta |
| Chronic exposure of zebrafish (Danio rerio) to flutolanil leads to endocrine disruption and reproductive disorders | Teng, M et. al. | Environmental Research |
| PGN and LTA from <i>Staphylococcus aureus</i> Induced Inflammation and Decreased Lactation through Regulating DNA Methylation and Histone H3 Acetylation in Bovine Mammary Epithelial Cells. | Wu Y, Chen J, Sun Y, Dong X, Wang Z, Chen J, Dong G | Toxins (Basel) |
| Effect of PFOA on DNA Methylation and Alternative Splicing in Mouse Liver. | Wen Y, Chen J, Li J, Arif W, Kalsotra A, Irudayaraj J | Toxicol Lett |
| Perfluorooctanoic acid (PFOA) exposure inhibits DNA methyltransferase activities and alters constitutive heterochromatin organization. | Liu W, Irudayaraj J | Food Chem Toxicol |
| Cross-sectional and longitudinal associations between global DNA (hydroxy) methylation and exposure biomarkers of the Hebei Spirit oil spill cohort in Taean, Korea | Chatterjee N et. al. | Environmental Pollution |
| Integrative Omics Analyses Reveal Epigenetic Memory in Diabetic Renal Cells Regulating Genes Associated With Kidney Dysfunction. | Bansal A, Balasubramanian S, Dhawan S, Leung A, Chen Z, Natarajan R | Diabetes |
| Pulmonary surfactant phosphatidylcholines induce immunological adaptation of alveolar macrophages. | da Costa Loureiro L, da Costa Loureiro L, Gabriel-Junior EA, Zambuzi FA, Fontanari C, Sales-Campos H, Frantz FG, Faccioli LH, Sorgi CA | Mol Immunol |
| Functional succinate dehydrogenase deficiency is a pathognomonic adverse feature of clear cell renal cancer | Aggarwal, R et. al. | biorxiv |
| Multi and transgenerational epigenetic effects of di-(2-ethylhexyl) phthalate (DEHP) in liver. | Wen Y, Rattan S, Flaws JA, Irudayaraj J | Toxicol Appl Pharmacol |
| Developmental and hormonal regulation of Ubiquitin-like with plant homeodomain and really interesting new gene finger domains 1 (UHRF1) gene expression in ovarian granulosa and theca cells of cattle. | Perego MC, Morrell BC, Zhang L, Schütz LF, Spicer LJ | J Anim Sci |
| Parental transgenerational epigenetic inheritance related to dietary crude oil exposure in <i>Danio rerio</i>. | Bautista NM, Crespel A, Crossley J, Padilla P, Burggren W | J Exp Biol |
| Bacteria pathogens drive host colonic epithelial cell promoter hypermethylation of tumor suppressor genes in colorectal cancer. | Xia X, Wu WKK, Wong SH, Liu D, Kwong TNY, Nakatsu G, Yan PS, Chuang YM, Chan MW, Coker OO, Chen Z, Yeoh YK, Zhao L, Wang X, Cheng WY, Chan MTV, Chan PKS, Sung JJY, Wang MH, Yu J | Microbiome |
| Anti-diabetic effect of a novel oligosaccharide isolated from Rosa caninavia via modulation of DNA methylation in Streptozotocin-diabetic rats. | Bahrami G, Sajadimajd S, Mohammadi B, Hatami R, Miraghaee S, Keshavarzi S, Khazaei M, Madani SH | Daru |
| PRMT1-dependent methylation of BRCA1 contributes to the epigenetic defense of breast cancer cells against ionizing radiation. | Montenegro MF, González-Guerrero R, Sánchez-Del-Campo L, Piñero-Madrona A, Cabezas-Herrera J, RodrÃguez-López JN | Sci Rep |
| Effects of mineral methionine hydroxy analogue chelate in sow diets on epigenetic modification and growth of progeny. | Jang K, Kim JH, Purvis JM, Chen J, Ren P, Vazquez-Anon M, Kim SW | J Anim Sci |
| Exposure to different early-life stress experiences results in differentially altered DNA methylation in the brain and immune system | Catale C. et. al. | Neurobiology of Stress |
| Differential DNA methylation in regulation of deacetylvindoline-4-O-acetyl transferase (DAT) gene in Catharanthus roseus | Parashar N.C, et. al. | Journal of Plant Biochemistry and Biotechnology |
| Deficient or Excess Folic Acid Supply During Pregnancy Alter Cortical Neurodevelopment in Mouse Offspring. | Harlan De Crescenzo A, Panoutsopoulos AA, Tat L, Schaaf Z, Racherla S, Henderson L, Leung KY, Greene NDE, Green R, Zarbalis KS | Cereb Cortex |
| Unmasking Unique Immune Altering Aspects of the Microbiome as a Tool to Correct Sepsis-Induced Immune Dysfunction. | Heffernan IM, McGeary JE, Chung CS, Ayala A, Heffernan DS | Surg Infect (Larchmt) |
| Transcriptomic and epigenomic effects of insoluble particles on J774 macrophages. | Emi T, Rivera LM, Tripathi VC, Yano N, Ragavendran A, Wallace J, Fedulov A | Epigenetics |
| HIV-1 Tat and cocaine impact mitochondrial epigenetics: effects on DNA methylation. | Doke M, Jeganathan V, McLaughlin JP, Samikkannu T | Epigenetics |
| Exome sequencing identifies frequent genomic loss of TET1 in IDH-wild-type glioblastoma. | Stasik S, Juratli TA, Petzold A, Richter S, Zolal A, Schackert G, Dahl A, Krex D, Thiede C | Neoplasia |
| Effect of neonatal exposure to endocrine-active compounds on epigenetic regulation of gene expression in corpus luteum of gilts. | Witek P, Grzesiak M, Kotula-Balak M, Koziorowski M, Slomczynska M, Knapczyk-Stwora K | Theriogenology |
| Genome-Wide DNA Methylation Variations Between Grass Carp with Different Ages | He L. et. al. | Research Square |
| Whole Genome 5'-Methylcytosine Level Quantification in Cirrhotic HCV-Infected Egyptian Patients with and without Hepatocellular Carcinoma. | Awad AM, Ragab WS, Degheidy N, Ooda SA | Int J Genomics |
| Critical window of exposure of CMIT/MIT with respect to developmental effects on zebrafish embryos: Multi-level endpoint and proteomics analysis. | Chatterjee N, Lee H, Kim J, Kim D, Lee S, Choi J | Environ Pollut |
| Effect of fluoride in drinking water on the level of 5-methylcytosine in human and rat blood. | Meng X, Yao Y, Ma Y, Zhong N, Alphonse S, Pei J | Environ Toxicol Pharmacol |
| Neural precursors cells expanded in a 3D microengineered niche present enhanced therapeutic efficacy in vivo | Carelli S. et. al. | Nanotheranostics |
| LKB1 Loss Upregulates ALKBH5 and Contributes to Aggressive Phenotypes of KRAS Mutated Lung Cancer | Zhang, D et. al. | Research Square |
| Cyclic DNA remethylation following active demethylation at euchromatic regions in mouse embryonic stem cells. | Kubiura-Ichimaru M, Ito T, Lefebvre L, Tada M | Chromosome Res |
| Glutathione Protects the Developing Heart from Defects and Global DNA Hypomethylation Induced by Prenatal Alcohol Exposure. | Jawaid S, Strainic JP, Kim J, Ford MR, Thrane L, Karunamuni GH, Sheehan MM, Chowdhury A, Gillespie CA, Rollins AM, Jenkins MW, Watanabe M, Ford SM | Alcohol Clin Exp Res |
| Strength training during pregnancy influences hippocampal plasticity but not body development in neonatal rats | Meireles A.L.F et. al. | J Musculoskelet Neuronal Interact |
| MBD2 serves as a viable target against pulmonary fibrosis by inhibiting macrophage M2 program. | Wang Y, Zhang L, Wu GR, Zhou Q, Yue H, Rao LZ, Yuan T, Mo B, Wang FX, Chen LM, Sun F, Song J, Xiong F, Zhang S, Yu Q, Yang P, Xu Y, Zhao J, Zhang H, Xiong W, Wang CY | Sci Adv |
| DNA methyltransferase 3B deficiency unveils a new pathological mechanism of pulmonary hypertension. | Yan Y, He YY, Jiang X, Wang Y, Chen JW, Zhao JH, Ye J, Lian TY, Zhang X, Zhang RJ, Lu D, Guo SS, Xu XQ, Sun K, Li SQ, Zhang LF, Zhang X, Zhang SY, Jing ZC | Sci Adv |
| Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations Under Maternal High-Fat Diet Intake: Multigenerational Epigenetic Inheritance. | Izquierdo, V. et. al. | Preprints |
| The anti-lipidemic drug simvastatin modifies epigenetic biomarkers in the amphipod Gammarus locusta. | Alves N, Neuparth T, Barros S, Santos MM | Ecotoxicol Environ Saf |
| Acute high folic acid treatment in SH-SY5Y cells with and without MTHFR function leads to gene expression changes in epigenetic modifying enzymes, changes in epigenetic marks, and changes in dendritic spine densities. | Clark DF, Schmelz R, Rogers N, Smith NE, Shorter KR | PLoS One |
| Decreased DNA hydroxymethylation and increased DNA demethylation are associated with high antioxidant response in systemic lupus erythematosus patients. | FragÃo Gil JJ, Grau GarcÃa E, Fernández Matilla M, Ortiz Sanjuan FM, Rodrigo Nicolás R, Román Ivorra JA | Med Clin (Barc) |
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| Effects of Acute Benzo[a]pyrene Exposure on Blood Clam Tegillarca Granosa: Histological Changes, Oxidative Stress, Neurotoxicity and DNA Hypomethylation | Guo B, et. al. | Research Square |
| Surface modification of electrospun fibers with mechano-growth factor for mitigating the foreign-body reaction | Song Y. et. al. | Bioactive Materials |
| The Dynamics of Metabolic Characterization in iPSC-Derived Kidney Organoid Differentiation <i>via</i> a Comparative Omics Approach. | Wang Q, Xiong Y, Zhang S, Sui Y, Yu C, Liu P, Li H, Guo W, Gao Y, Przepiorski A, Davidson AJ, Guo M, Zhang X | Front Genet |
| DNA methylation and gene expression alterations in zebrafish embryos exposed to cadmium. | Bian X, Gao Y | Environ Sci Pollut Res Int |
| Ultra performance liquid chromatography-tandem mass spectrometry assay for the quantification of RNA and DNA methylation. | Chang JS, Lin ZX, Liu YJ, Yang SM, Zhang Y, Yu XY | J Pharm Biomed Anal |
| First-in-human study of inhaled Azacitidine in patients with advanced non-small cell lung cancer. | Cheng H, Zou Y, Shah CD, Fan N, Bhagat TD, Gucalp R, Kim M, Verma A, Piperdi B, Spivack SD, Halmos B, Perez-Soler R | Lung Cancer |
| An altered global DNA methylation status in women with depression. | Reszka E, Jabłońska E, Lesicka M, Wieczorek E, Kapelski P, Szczepankiewicz A, Pawlak J, Dmitrzak-Węglarz M | J Psychiatr Res |
| Ten-eleven translocation methylcytosine dioxygenase 3-loaded microspheres penetrate neurons in vitro causing active demethylation and neurite outgrowth. | Nawrotek K, Rudnicka K, Gatkowska J, Michlewska S, Pearson BL, Płociński P, Wieczorek M | J Tissue Eng Regen Med |
| Biological and epigenetic alterations of mitochondria involved in cellular replicative and hydrogen peroxide-induced premature senescence of human embryonic lung fibroblasts. | Wang Y, Gao J, Wu F, Lai C, Li Y, Zhang G, Peng X, Yu S, Yang J, Wang W, Zhang W, Yang X | Ecotoxicol Environ Saf |
| Hydrogen sulfide prevents ethanol-induced ZO-1 CpG promoter hypermethylation-dependent vascular permeability via miR-218/DNMT3a axis. | Behera J, Kelly KE, Tyagi N | J Cell Physiol |
| Epigenetic effects of insecticides on early differentiation of mouse embryonic stem cells. | Wang W, Ito T, Otsuka S, Nansai H, Abe K, Nakao Y, Ohgane J, Yoneda M, Sone H | Toxicol In Vitro |
| Transgenerational effects in DNA methylation, genotoxicity and reproductive phenotype by chronic arsenic exposure. | Nava-Rivera LE, Betancourt-MartÃnez ND, Lozoya-MartÃnez R, Carranza-Rosales P, Guzmán-Delgado NE, Carranza-Torres IE, Delgado-Aguirre H, Zambrano-OrtÃz JO, Morán-MartÃnez J | Sci Rep |
| DNMT3B Is an Oxygen-Sensitive De Novo Methylase in Human Mesenchymal Stem Cells. | Dogan F, Aljumaily RMK, Kitchen M, Forsyth NR | Cells |
| Comparative profiling of epigenetic modifications among individuals living in different high and low air pollution zones: A pilot study from India | Mishra P. K. | medRxiv |
| Cannabis alters epigenetic integrity and endocannabinoid signalling in the human follicular niche. | Fuchs Weizman N, Wyse BA, Szaraz P, Defer M, Jahangiri S, Librach CL | Hum Reprod |
| Increased PARylation impacts the DNA methylation process in type 2 diabetes mellitus. | Zampieri M, Bacalini MG, Barchetta I, Scalea S, Cimini FA, Bertoccini L, Tagliatesta S, De Matteis G, Zardo G, Cavallo MG, Reale A | Clin Epigenetics |
| Distinguishing Active Versus Passive DNA Demethylation Using Illumina MethylationEPIC BeadChip Microarrays. | Tiedemann RL, Eden HE, Huang Z, Robertson KD, Rothbart SB | Methods Mol Biol |
| Suppression of m6A mRNA modification by DNA hypermethylated ALKBH5 aggravates the oncological behavior of KRAS mutation/LKB1 loss lung cancer. | Zhang D, Ning J, Okon I, Zheng X, Satyanarayana G, Song P, Xu S, Zou MH | Cell Death Dis |
| Persistence of Coxsackievirus B4 in Pancreatic β Cells Disturbs Insulin Maturation, Pattern of Cellular Proteins, and DNA Methylation. | Nekoua MP, Bertin A, Sane F, Gimeno JP, Fournier I, Salzet M, Engelmann I, Alidjinou EK, Hober D | Microorganisms |
| Early-life exposure to tris (1,3-dichloro-2-propyl) phosphate caused multigenerational neurodevelopmental toxicity in zebrafish via altering maternal thyroid hormones transfer and epigenetic modifications. | Li R, Yang L, Han J, Zou Y, Wang Y, Feng C, Zhou B | Environ Pollut |
| Maternal n-3 PUFA deficiency alters uterine artery remodeling and placental epigenome in the mice. | Srinivas V, Molangiri A, Mallepogu A, Kona SR, Ibrahim A, Duttaroy AK, Basak S | J Nutr Biochem |
| Alpha-Synuclein-induced DNA Methylation and Gene Expression in Microglia. | McGregor BA, Schommer J, Guo K, Obayed Raihan M, Ghribi O, Hur J, Porter JE | Neuroscience |
| Epigenetic effect of the mycotoxin Fumonisin B1 on DNA methylation. | Sugiyama KI, Kinoshita M, Furusawa H, Sato K, Honma M | Mutagenesis |
| Exercise attenuates low back pain and alters epigenetic regulation in intervertebral discs in a mouse model. | Kawarai Y, Jang SH, Lee S, Millecamps M, Kang H, Gregoire S, Suzuki-Narita M, Ohtori S, Stone LS | Spine J |
| HeLa TI cell-based assay as a new approach to screen for chemicals able to reactivate the expression of epigenetically silenced genes. | Maksimova V, Shalginskikh N, Vlasova O, Usalka O, Beizer A, Bugaeva P, Fedorov D, Lizogub O, Lesovaya E, Katz R, Belitsky G, Kirsanov K, Yakubovskaya M | PLoS One |
| Activation of DNA methyltransferase 3a by Epstein-Barr nuclear antigen 1 in gastric carcinoma. | Song H, Zhang Y, Liu J, Liu W, Luo B | Dig Liver Dis |
| Global DNA methylation and cellular 5-methylcytosine and H4 acetylated patterns in primary and secondary dormant seeds of Capsella bursa-pastoris (L.) Medik. (shepherd's purse). | Gomez-Cabellos S, Toorop PE, Cañal MJ, Iannetta PPM, Fernández-Pascual E, Pritchard HW, Visscher AM | Protoplasma |
| Global DNA methylation level in females with idiopathic scoliosis. | Janusz P, Chmielewska M, Andrusiewicz M, Kotwicki T, Kotwicka M | Stud Health Technol Inform |
| Gene body DNA methylation in seagrasses: inter- and intraspecific differences and interaction with transcriptome plasticity under heat stress. | Entrambasaguas L, Ruocco M, Verhoeven KJF, Procaccini G, MarÃn-Guirao L | Sci Rep |
| Potential effect of tobacco cigarettes smoking on global DNA methylation status and protamines transcripts in human spermatozoa | Laqqan, M., Yassin, M. | Middle East Fertility Society Journal |
| Exposure to hypomethylating 5-aza-2′-deoxycytidine (decitabine) causes rapid, severe DNA damage, telomere elongation and mitotic dysfunction in human WIL2-NS cells | Bull, C. et. al. | Mutation Research/Genetic Toxicology and Environmental Mutagenes |
| Metabolic Evidence Rather Than Amounts of Red or Processed Meat as a Risk on Korean Colorectal Cancer | Kim, E. et. al. | Metabolites |
| The splicing regulator SLU7 is required to preserve DNMT1 protein stability and DNA methylation. | Recalde M, Gárate-Rascón M, Elizalde M, Azkona M, Latasa MU, Bárcena-Varela M, Sangro B, Fernández-Barrena MG, Ãvila MA, Arechederra M, Berasain C | Nucleic Acids Res |
| Epigenetic modifications underlie the differential adipogenic potential of preadipocytes derived from human subcutaneous fat tissue. | Kubota Y, Nagano H, Kosaka K, Ogata H, Nakayama A, Yokoyama M, Murata K, Akita S, Kuriyama M, Furuyama N, Kuroda M, Tanaka T, Mitsukawa N | Am J Physiol Cell Physiol |
| Generational effects of a chronic exposure to a low environmentally relevant concentration of glyphosate on rainbow trout, Oncorhynchus mykiss | Le Du-Carrée, J. et. al. | Science of The Total Environment |
| Methylation profile of hepatitis B virus is not influenced by interferon α in human liver cancer cells. | Moon IY, Kim JW | Mol Med Rep |
| DNA Methyltransferases Regulate Pathogenicity of Botrytis cinerea to Horticultural Crops | Zhang, Z. et. al. | J. Fungi |
| PAX7 Balances the Cell Cycle Progression via Regulating Expression of Dnmt3b and Apobec2 in Differentiating PSCs | Florkowska A., et. al. | Cells |
| Antitumoral activity of liraglutide, a new DNMT inhibitor in breast cancer cells in vitro and in vivo. | Chequin A, Costa LE, de Campos FF, Moncada ADB, de Lima LTF, Sledz LR, Picheth GF, Adami ER, Acco A, Gonçalves MB, Manica GCM, Valdameri G, de Noronha L, Telles JEQ, Jandrey EHF, Costa ET, Costa FF, de Souza EM, Ramos EAS, Klassen G | Chem Biol Interact |
| Exposure to glyphosate and tetrachlorvinphos induces cytotoxicity and global DNA methylation in human cells. | Ergun H, Cayir A | Toxicol Ind Health |
| Acute benzo[a]pyrene exposure induced oxidative stress, neurotoxicity and epigenetic change in blood clam Tegillarca granosa. | Guo B, Feng D, Xu Z, Qi P, Yan X | Sci Rep |
| Transposon-triggered innate immune response confers cancer resistance to the blind mole rat. | Zhao Y, Oreskovic E, Zhang Q, Lu Q, Gilman A, Lin YS, He J, Zheng Z, Lu JY, Lee J, Ke Z, Ablaeva J, Sweet MJ, Horvath S, Zhang Z, Nevo E, Seluanov A, Gorbunova V | Nat Immunol |
| Differential DNA methylation and transcriptional signatures characterize impairment of muscle stem cells in pediatric human muscle contractures after brain injury. | Sibley LA, Broda N, Gross WR, Menezes AF, Embry RB, Swaroop VT, Chambers HG, Schipma MJ, Lieber RL, Domenighetti AA | FASEB J |
| lnc-MAP3K13-7:1 Inhibits Ovarian GC Proliferation in PCOS via DNMT1 Downregulation-Mediated CDKN1A Promoter Hypomethylation. | Geng X, Zhao J, Huang J, Li S, Chu W, Wang WS, Chen ZJ, Du Y | Mol Ther |
| Effects of tributyltin on retinoid X receptor gene expression and global DNA methylation during intracapsular development of the gastropod Tritia mutabilis (Linnaeus, 1758). | Cocci P, Mosconi G, Palermo FA | Environ Toxicol Pharmacol |
| Folate metabolism modifies chromosomal damage induced by 1,3-butadiene: results from a match-up study in China and in vitro experiments. | Xiang M, Wang Z, Zou P, Ling X, Zhang G, Zhou Z, Cao J, Ao L | Genes Environ |
| Inhibition of 11β-HSD1 Ameliorates Cognition and Molecular Detrimental Changes after Chronic Mild Stress in SAMP8 Mice | Puigoriol-Illamola, D. et al. | Pharmaceuticals |
| DNA Methylation Profiles of Ovarian Granular Cells from Fluorosis Female Patients Suffering Reproductive Dysfunctions. | He B, Dong S, Chen Q, Dong Z, Chen C | Biol Trace Elem Res |
| Intergenerational Patterns of DNA Methylation in Procambarus clarkii Following Exposure to Genotoxicants: A Conjugation in Past Simple or Past Continuous? | Marçal, R. et. al. | Toxics |
| DNA Methylation Profiles of Ovarian Granular Cells from Fluorosis Female Patients Suffering Reproductive Dysfunctions. | He B, Dong S, Chen Q, Dong Z, Chen C | Biol Trace Elem Res |
| Evidence for age-related contributions of DNA damage and epigenetics in brain tumorigenesis. | Tira A, Buckingham L | Int J Exp Pathol |
| DNA methylation profile in patients with indolent systemic mastocytosis. | Górska A, Jabłońska E, Reszka E, Niedoszytko M, Lange M, Gruchała-Niedoszytko M, Jarczak J, Strapagiel D, Górska-Ponikowska M, Bastian P, Pelikant-Małecka I, Kalinowski L, Nedoszytko B | Clin Transl Allergy |
| Unique Features of mRNA m6A Methylomes During Expansion of Tomato (Solanum lycopersicum) Fruits. | Hu J, Cai J, Umme A, Chen Y, Xu T, Kang H | Plant Physiol |
| KLF4, DAPK1 and SPG20 promoter methylation is not affected by DNMT1 silencing and hypomethylating drugs in lymphoma cells. | Frazzi R, Cusenza VY, Pistoni M, Canovi L, Cascione L, Bertoni F, Merli F | Oncol Rep |
| Fine-grained investigation of the relationship between human nutrition and global DNA methylation patterns. | Noro F, Marotta A, Bonaccio M, Costanzo S, Santonastaso F, Orlandi S, Tirozzi A, Parisi R, De Curtis A, Persichillo M, Gianfagna F, Di Castelnuovo A, Donati MB, Cerletti C, de Gaetano G, Iacoviello L, Gialluisi A, Izzi B | Eur J Nutr |
| Molecular Responses of Arabidopsis MET1 Cytosine Methyltransferase Mutants To Salinity | Yeşildirek Y.V., Arıkan B., Kara, N.T. | Research Square |
| Therapeutic Effects of Dietary Soybean Genistein on Triple-Negative Breast Cancer via Regulation of Epigenetic Mechanisms. | Sharma M, Arora I, Chen M, Wu H, Crowley MR, Tollefsbol TO, Li Y | Nutrients |
| Influence of tobacco cigarette heavy smoking on DNA methylation patterns and transcription levels of MAPK8IP3, GAA, ANXA2, PRRC2A, and PDE11A genes in human spermatozoa | Laqqan, M.M., Yassin, M.M | Middle East Fertil Soc J |
| Prenatal exposure to polycyclic aromatic hydrocarbons could increase the risk of low birth weight by affecting the DNA methylation states in a Chinese cohort. | Cao C, Jia Z, Shao M, Li R, Sun Q, Liu D | Reprod Biol |
| Effects of Cadmium Sulfate on the Brown Garden Snail Cornu aspersum: Implications for DNA Methylation | Georgescu, M. et. al. | Toxics |
| Cigarette heavy smoking alters DNA methylation patterns and gene transcription levels in humans spermatozoa. | Laqqan MM, Yassin MM | Environ Sci Pollut Res Int |
| Association of air pollution and homocysteine with global DNA methylation: A population-based study from North India. | Yadav S, Longkumer I, Garg PR, Joshi S, Rajkumari S, Devi NK, Saraswathy KN | PLoS One |
| Mitochondrial C1qbp promotes differentiation of effector CD8<sup>+</sup> T cells via metabolic-epigenetic reprogramming. | Zhai X, Liu K, Fang H, Zhang Q, Gao X, Liu F, Zhou S, Wang X, Niu Y, Hong Y, Lin SH, Liu WH, Xiao C, Li Q, Xiao N | Sci Adv |
| Impact of maternal dietary counseling in the first year of life on DNA methylation in a cohort of children. | Castilhos JK, Campagnolo PDB, Almeida S, Vitolo MR, Mattevi VS | Genet Mol Biol |
| Evaluation of Global DNA Methylation and Gene Expression of Izumo1 and Izumo1r in Gonads after High- and Low-Dose Radiation in Neonatal Mice | Nakata A. et. al. | Biology |
| Epigenetic alterations associated with dexamethasone sodium phosphate through DNMT and TET in RPE cells | Liu, W. et. al. | Molecular Vision |
| Small molecule epigenetic modulators for enhancing recombinant antibody production in CHO cell cultures. | Kim D, Yoon C, Lee GM | Biotechnol Bioeng |
| Aqueous Extract of Alstonia boonei Bark Reduces Chronic Hyperglycemia and Prevents its Complications through Increase of Hepatic Global Dna Methylation in Diabetic Wistar Rats | Fonkoua, M., et. al. | European Journal of Medicinal Plants |
| AntiGan: An Epinutraceutical Bioproduct with Antitumor Properties in Cultured Cell Lines | MartÃnez-Iglesias O. et. al. | Life |
| Global DNA Methylation in Dental Implant Failure Due to Peri-Implantitis: An Exploratory Clinical Pilot Study | Khouly I., et. al. | Int J Environ Res Public Health |
| An integrative analysis of DNA methylation and transcriptome showed the dysfunction of MAPK pathway was involved in the damage of human chondrocyte induced by T-2 toxin. | Yang X, Xiao X, Zhang L, Wang B, Li P, Cheng B, Liang C, Ma M, Guo X, Zhang F, Wen Y | BMC Mol Cell Biol |
| Global DNA Methylation in Dental Implant Failure Due to Peri-Implantitis: An Exploratory Clinical Pilot Study. | Khouly I, Pardiñas López S, DÃaz Prado SM, Ferrantino L, Kalm J, Larsson L, Asa'ad F | Int J Environ Res Public Health |
| Effects of paternal exposure to cigarette smoke on sperm DNA methylation and long-term metabolic syndrome in offspring. | Liu Y, Chen S, Pang D, Zhou J, Xu X, Yang S, Huang Z, Yu B | Epigenetics Chromatin |
| HIV-1 Tat and cocaine coexposure impacts piRNAs to affect astrocyte energy metabolism. | Doke M, Kashanchi F, Khan MA, Samikkannu T | Epigenomics |
| Semen quality and sperm DNA methylation in relation to long-term exposure to air pollution in fertile men: A cross-sectional study. | Cheng Y, Tang Q, Lu Y, Li M, Zhou Y, Wu P, Li J, Pan F, Han X, Chen M, Lu C, Wang X, Wu W, Xia Y | Environ Pollut |
| Acute effects of endurance exercise on Global DNA methylation after a high intensity and moderate intensity intervention – A methodological study | De Lazzari, N. et. al. | Journal Of Medical Case Reports And Case Series |
| Neurogenesis in the neonatal rat hippocampus is regulated by sexually dimorphic epigenetic modifiers. | Stockman SL, Kight KE, Bowers JM, McCarthy MM | Biol Sex Differ |
| Triclosan (TCS) affects the level of DNA methylation in the human oral squamous cell carcinoma (SCC-15) cell line in a nontoxic concentration. | Szychowski KA, Skóra B, Bar M, Piechowiak T | Biomed Pharmacother |
| AAV-mediated expression of secreted and transmembrane αKlotho isoforms rescues relevant aging hallmarks in senescent SAMP8 mice. | Roig-Soriano J, Griñán-Ferré C, Espinosa-Parrilla JF, Abraham CR, Bosch A, Pallàs M, Chillón M | Aging Cell |
| DNMTs Are Involved in TGF-β1-Induced Epithelial-Mesenchymal Transitions in Airway Epithelial Cells | Park, J. H., et. al . | Int. J. Mol. Sci. |
| Cumulative Metabolic and Epigenetic Effects of Paternal and/or Maternal Supplementation with Arachidonic Acid across Three Consecutive Generations in Mice. | de la Rocha C, RodrÃguez-RÃos D, RamÃrez-Chávez E, Molina-Torres J, de Jesús Flores-Sierra J, Orozco-Castellanos LM, Galván-ChÃa JP, Sánchez AV, Zaina S, Lund G | Cells |
| Epigenetic and post-transcriptional repression support metabolic suppression in chronically hypoxic goldfish. | Farhat E, Talarico GGM, Grégoire M, Weber JM, Mennigen JA | Sci Rep |
| Carbon monoxide activates PERK-regulated autophagy to induce immunometabolic reprogramming and boost anti-tumor T cell function. | Chakraborty P, Parikh RY, Choi S, Tran D, Gooz M, Hedley ZT, Kim DS, Pytel D, Kang I, Nadig SN, Beeson GC, Ball L, Mehrotra M, Wang H, Berto S, Palanisamy V, Li H, Chatterjee S, Rodriguez PC, Maldonado EN, Diehl JA, Gangaraju VK, Mehrotra S | Cancer Res |
| Genome-wide DNA methylation reveals potential epigenetic mechanism of age-dependent viral susceptibility in grass carp. | He L, Liang X, Wang Q, Yang C, Li Y, Liao L, Zhu Z, Wang Y | Immun Ageing |
| Evidence for TET-mediated DNA demethylation as an epigenetic alteration in cumulus granulosa cells of women with polycystic ovary syndrome. | Sagvekar P, Shinde G, Mangoli V, Desai SK, Mukherjee S | Mol Hum Reprod |
| Epigenetic regulation of BAF60A determines efficiency of miniature swine iPSC generation. | Jiao H, Lee MS, Sivapatham A, Leiferman EM, Li WJ | Sci Rep |
| Prenatal exposure to environmental pro-oxidants induces mitochondria-mediated epigenetic changes: a cross-sectional pilot study. | Mishra PK, Kumari R, Bhargava A, Bunkar N, Chauhan P, Tiwari R, Shandilya R, Srivastava RK, Singh RD | Environ Sci Pollut Res Int |
| Changes in global DNA methylation under climatic stress in two related grasses suggest a possible role of epigenetics in the ecological success of polyploids. | Tomczyk PP, Kiedrzyński M, Forma E, Zielińska KM, Kiedrzyńska E | Sci Rep |
| Gibbin mesodermal regulation patterns epithelial development. | Collier A, Liu A, Torkelson J, Pattison J, Gaddam S, Zhen H, Patel T, McCarthy K, Ghanim H, Oro AE | Nature |
| Transgenerational herbivory effects on performance of clonal offspring of the invasive plant Alternanthera philoxeroides | FU, Q.Y., et. al. | Research Square |
| A study on DNA methylation modifying natural compounds identified EGCG for induction of IFI16 gene expression related to the innate immune response in cancer cells | Khan, M. I., et. al. | Oncology Letters |
| Prolonged exposure of azocyclotin induced inter- and transgenerational endocrine disruption on Danio rerio linked to transcriptomic and DNA methylomic alterations. | Jiao F, Ma Y, Hu T, Qiao K, Jiang Y, Zhu W, Jin Q, Gui W | Chemosphere |
| Investigating the role of DNMT1 gene expression on myocardial ischemia reperfusion injury in rat and associated changes in mitochondria. | Boovarahan SR, Kurian GA | Biochim Biophys Acta Bioenerg |
| Linking Arsenic, DNA Methylation Biomarkers, and Transgenerational Neurotoxicity: Modeling in Zebrafish | Hernandez-Sanchez J., Valles S., Bardullas U. | Biomarkers in Toxicology |
| Regular Intake of Green Tea Polyphenols Suppresses the Development of Nonmelanoma Skin Cancer through miR-29-Mediated Epigenetic Modifications. | Kansal V, Agarwal A, Harbour A, Farooqi H, Singh VK, Prasad R | J Clin Med |
| Microcystin-leucine-arginine affects brain gene expression programs and behaviors of offspring through paternal epigenetic information. | Xu J, Zhang W, Zhong S, Xie X, Che H, Si W, Tuo X, Xu D, Zhao S | Sci Total Environ |
| Maternal soybean diet on prevention of obesity-related breast cancer through early-life gut microbiome and epigenetic regulation. | Chen M, Li S, Arora I, Yi N, Sharma M, Li Z, Tollefsbol TO, Li Y | J Nutr Biochem |
| DNA hypermethylation promotes the flowering of orchardgrass during vernalization. | Yang Z, Yan H, Wang J, Nie G, Feng G, Xu X, Li D, Huang L, Zhang X | Plant Physiol |
| The DNA methylation landscape of the root-knot nematode-induced pseudo-organ, the gall, in Arabidopsis, is dynamic, contrasting over time, and critically important for successful parasitism. | Silva AC, Ruiz-Ferrer V, Müller SY, Pellegrin C, Abril-UrÃas P, MartÃnez-Gómez Ã, Gómez-Rojas A, Berenguer E, Testillano PS, Andrés MF, Fenoll C, Eves-van den Akker S, Escobar C | New Phytol |
| Bisphenol-A reduces DNA methylation after metabolic activation. | Sugiyama KI, Kinoshita M, Grúz P, Kasamatsu T, Honma M | Genes Environ |
| SHF Acts as a Novel Tumor Suppressor in Glioblastoma Multiforme by Disrupting STAT3 Dimerization. | Wang J, Huang Z, Ji L, Chen C, Wan Q, Xin Y, Pu Z, Li K, Jiao J, Yin Y, Hu Y, Gong L, Zhang R, Yang X, Fang X, Wang M, Zhang B, Shao J, Zou J | Adv Sci (Weinh) |
| Paternal alcohol exposure has task- and sex-dependent behavioral effect in offspring. | Nieto SJ, Harding MJ, Nielsen DA, Kosten TA | Alcohol Clin Exp Res |
| Role of multiple risk factors in mental disorders diagnosed in middle-aged women: A population-based follow-up study. | Wang X, Memon AA, Palmér K, Hedelius A, Sundquist J, Sundquist K | J Psychiatr Res |
| Comparative study of the cytotoxicity, apoptotic, and epigenetic effects of Boswellic acid derivatives on breast cancer. | Jamshidi-Adegani F, Ghaemi S, Al-Hashmi S, Vakilian S, Al-Kindi J, Rehman NU, Alam K, Al-Riyami K, Csuk R, Arefian E, Al-Harrasi A | Sci Rep |
| Associations of fertility parameters with fatty acids and DNA methylation in Mexican women undergoing in vitro fertilization. | Zúñiga-Sánchez P, González-Ortega C, Cancino-Villarreal P, MartÃnez-Garza S, Molina-Torres J, RamÃrez-Chávez E, Gutiérrez-Gutiérrez AM, Lund G, Zaina S | Int J Obes (Lond) |
| The Matricellular Protein SPARC Decreases in the Lacrimal Gland At Adulthood and During Inflammation. | Feldt J, Garriz A, Rodriguez Benavente MC, Woodward AM, Zoukhri D, Argüeso P | Invest Ophthalmol Vis Sci |
| A Cautionary Tale of Sexing by Methylation: Hybrid Bisulfite-Conversion Sequencing of Immunoprecipitated Methylated DNA in Chrysemys picta Turtles with Temperature-Dependent Sex Determination Reveals Contrasting Patterns of Somatic and Gonadal Methylation, but No Unobtrusive Sex Diagnostic. | Mizoguchi BA, Valenzuela N | Animals (Basel) |
| Hydroxytyrosol decreases EDNRA expression through epigenetic modification in colorectal cancer cells. | Del Saz-Lara A, Boughanem H, López de Las Hazas MC, Crespo C, Saz-Lara A, Visioli F, Macias-González M, Dávalos A | Pharmacol Res |
| Diabetic Hearts Exhibit Global DNA Hypermethylation That Alter the Mitochondrial Functional Genes to Enhance the Sensitivity of the Heart to Ischemia Reperfusion Injury. | Boovarahan SR, Chellappan DR, Ali N, AlAsmari AF, Waseem M, Alabdulrahim AS, Alzahrani ZA, Kurian GA | Biomedicines |
| DNA Methylation Alterations in Fractionally Irradiated Rats and Breast Cancer Patients Receiving Radiotherapy. | Sallam M, Mysara M, Benotmane MA, Crijns APG, Spoor D, Van Nieuwerburgh F, Deforce D, Baatout S, Guns PJ, Aerts A, Ramadan R | Int J Mol Sci |
| Association of nutritional glycaemic indices with global DNA methylation patterns: results from the Moli-sani cohort. | Noro F, Santonastaso F, Marotta A, Bonaccio M, Orlandi S, Tirozzi A, Costanzo S, De Curtis A, Gianfagna F, Di Castelnuovo A, Brighenti F, Cerletti C, Donati MB, de Gaetano G, Iacoviello L, Gialluisi A, Izzi B | Clin Epigenetics |
| Pivotal role for S-nitrosylation of DNA methyltransferase 3B in epigenetic regulation of tumorigenesis. | Okuda K, Nakahara K, Ito A, Iijima Y, Nomura R, Kumar A, Fujikawa K, Adachi K, Shimada Y, Fujio S, Yamamoto R, Takasugi N, Onuma K, Osaki M, Okada F, Ukegawa T, Takeuchi Y, Yasui N, Yamashita A, Marusawa H, Matsushita Y, Katagiri T, Shibata T, Uchida K, Niu SY, Lang NB, Nakamura T, Zhang KYJ, Lipton SA, Uehara T | Nat Commun |
| Oxidized mC modulates synthetic lethality to PARP inhibitors for the treatment of leukemia. | Brabson JP, Leesang T, Yap YS, Wang J, Lam MQ, Fang B, Dolgalev I, Barbieri DA, Strippoli V, Bañuelos CP, Mohammad S, Lyon P, Chaudhry S, Donich D, Swirski A, Roberts E, Diaz I, Karl D, Dos Santos HG, Shiekhattar R, Neel BG, Nimer SD, Verdun RE, Bilbao D, Figueroa ME, Cimmino L | Cell Rep |
| DNA Hypomethylation Is Associated with Increased Inflammation in Peripheral Blood Neutrophils of Children with Autism Spectrum Disorder: Understanding the Role of Ubiquitous Pollutant Di(2-ethylhexyl) Phthalate. | Alshamrani AA, Alshehri S, Alqarni SS, Ahmad SF, Alghibiwi H, Al-Harbi NO, Alqarni SA, Al-Ayadhi LY, Attia SM, Alfardan AS, Bakheet SA, Nadeem A | Metabolites |
| Cadmium nitrate and DNA methylation in gastropods: comparison between ovotestis and hepatopancreas. | Draghici GA, Dehelean CA, Moaca AE, Moise ML, Pinzaru I, Vladut VN, Banatean-Dunea I, Nica D | PeerJ |
| Experimental DNA Demethylation Reduces Expression Plasticity and Thermal Tolerance in Pacific Oysters. | Wang X, Cong R, Li A, Wang W, Zhang G, Li L | Mar Biotechnol (NY) |
| Trans- and Multigenerational Effects of Isothiazolinone Biocide CMIT/MIT on Genotoxicity and Epigenotoxicity in Daphnia magna. | Kim J, Choi J | Toxics |
| High dietary folate and low vitamin B12 in the parental diet disturbed the epigenetics of imprinted genes MEST and PHLDA2 in mice placenta. | Sapehia D, Mahajan A, Singh P, Kaur J | J Nutr Biochem |
| Insights into the mechanisms of within-species variation in sensitivity to chemicals: A case study using daphnids exposed to CMIT/MIT biocide. | Kim J, Coutellec MA, Lee S, Choi J | Ecotoxicol Environ Saf |
| Hematological Consequences of Polyethylene Microplastics Toxicity in Male Rats: Oxidative stress, Genetic, and Epigenetic links. | Farag AA, Youssef HS, Sliem RE, El Gazzar WB, Nabil N, Mouktar MM, Marei YM, Ismail NS, Radwaan SE, Badr AM, Sayed AEH | Toxicology |
| Effects of fecal microbiota transplant on DNA methylation in patients with systemic lupus erythematosus. | Zhang B, Zhou W, Liu Q, Huang C, Hu Z, Zheng M, Xin Y, Zhao M, Lu Q | J Autoimmun |
| Knockout of TRDMT1 methyltransferase affects DNA methylome in glioblastoma cells. | Zabek T, Szmatola T, Adamczyk-Grochala J, Lewinska A, Wnuk M | J Neurooncol |
| Epigenetic-Based Regulation of Transcriptome in Escherichia coli Adaptive Antibiotic Resistance. | D'Aquila P, De Rango F, Paparazzo E, Passarino G, Bellizzi D | Microbiol Spectr |
| Cystathionine γ-synthase expression in seeds alters metabolic and DNA methylation profiles in Arabidopsis. | Girija A, Hacham Y, Dvir S, Panda S, Lieberman-Lazarovich M, Amir R | Plant Physiol |
| KDM2A interacts with estrogen receptor α to promote bisphenol A and S-induced breast cancer cell proliferation by repressing TET2 expression. | Li Z, Ren Y, Li X, Wang W | Ecotoxicol Environ Saf |
| Xiao Chai Hu Tang alleviates the pancreatic tumorigenesis via improving the mtDNA N6-Methyladenine modification mediated mitochondrial dysfunction in Syrian hamster model. | Cai J, Shen W, Zhang G, Li X, Shen H, Li W, Tan C, Zhang T, Shi M, Yang Z, Li Y, Liu H, Zhao X | Phytomedicine |
| Mu opioid receptor expressing neurons in the rostral ventromedial medulla are the source of mechanical hypersensitivity induced by repeated restraint stress. | Imbe H, Ihara H | Brain Res |
| Jieduquyuziyin prescription enhances CD11a and CD70 DNA methylation of CD4(+) T cells via miR-29b-sp1/DNMT1 pathway in MRL/lpr mice. | Huang S, Peng J, Gan Y, Chen L, Zhu Z, Tian F, Ji L, Fan Y, Zhou C, Bao J | J Ethnopharmacol |
| CABG Patients Develop Global DNA Hypermethylation, That Negatively Affect the Mitochondrial Function and Promote Post-Surgical Cognitive Decline: A Proof of Concept in Small Cohort. | Boovarahan SR, Kale SB, Prem PN, Ravindran S, Arthanarisami A, Rengaraju J, Ali N, Ramalingam S, Mohany M, AlAsmari AF, Al-Rejaie SS, Waseem M, Kurian GA | J Clin Med |
| Reduction of Intracellular Tension and Cell Adhesion Promotes Open Chromatin Structure and Enhances Cell Reprogramming. | Soto J, Song Y, Wu Y, Chen B, Park H, Akhtar N, Wang PY, Hoffman T, Ly C, Sia J, Wong S, Kelkhoff DO, Chu J, Poo MM, Downing TL, Rowat AC, Li S | Adv Sci (Weinh) |
| Effects of the loss of maternal gut microbiota before pregnancy on gut microbiota, food allergy susceptibility, and epigenetic modification on subsequent generations. | Aizawa S, Uebanso T, Shimohata T, Mawatari K, Takahashi A | Biosci Microbiota Food Health |
| Elovanoids are neural resiliency epigenomic regulators targeting histone modifications, DNA methylation, tau phosphorylation, telomere integrity, senescence programming, and dendrite integrity. | Bazan N, Bhattacharjee S, Kala-Bhattacharjee S, Ledet A, Mukherjee P | Res Sq |
| Nuclear and chromatin rearrangement associate to epigenome and gene expression changes in a model of in vitro adipogenesis and hypertrophy. | Baldini F, Zeaiter L, Diab F, Zbeeb H, Cuneo L, Pagano A, Portincasa P, Diaspro A, Vergani L | Biochim Biophys Acta Mol Cell Biol Lipids |
| Variation in habitat use and its consequences for mercury exposure in two Eastern Ontario bat species, Myotis lucifugus and Eptesicus fuscus. | Bedard B, Hickey B, Chételat J, Mennigen JA | Ecotoxicology |
| Downregulation of MGMT expression by targeted editing of DNA methylation enhances temozolomide sensitivity in glioblastoma. | Han X, Abdallah MOE, Breuer P, Stahl F, Bakhit Y, Potthoff AL, Pregler BEF, Schneider M, Waha A, Wüllner U, Evert BO | Neoplasia |
| DNA methylation cooperates with H3K9me2 at HCN4 promoter to regulate the differentiation of bone marrow mesenchymal stem cells into pacemaker-like cells. | Sun X, Jin K, Ding X, Ruan Z, Xu P | PLoS One |
| Epigenetic Modifications Related to Potato Skin Russeting. | Kumar P, Kaplan Y, Endelman JB, Ginzberg I | Plants (Basel) |
| In Vivo Identification of H3K9me2/H3K79me3 as an Epigenetic Barrier to Carcinogenesis. | Piro MC, Gasperi V, De Stefano A, Anemona L, Cenciarelli CR, Montanaro M, Mauriello A, Catani MV, Terrinoni A, Gambacurta A | Int J Mol Sci |
| The influence of Salvia cadmica Boiss. extracts on the M1/M2 polarization of macrophages primed with Helicobacter pylori lipopolysaccharide in conjunction with NF-kappa B activation, production of cytokines, phagocytic activity and total DNA methylation. | Gonciarz W, PiÄ…tczak E, Chmiela M | J Ethnopharmacol |
| Knocking down a DNA demethylase gene affects potato plant defense against a specialist insect herbivore. | Zhang Y, Zhong J, Munawar A, Cai Y, He W, Zhang Y, Guo H, Gao Y, Zhu Z, Zhou W | J Exp Bot |
| Mixed Connective Tissue Disease as Different Entity: Global Methylation Aspect. | Filipowicz G, Wajda A, Stypińska B, Kmiołek T, Felis-Giemza A, Stańczyk S, Czuszyńska Z, Walczyk M, Olesińska M, Paradowska-Gorycka A | Int J Mol Sci |
| Evaluation and Mechanistic Study of Transgenerational Neurotoxicity in Zebrafish upon Life Cycle Exposure to Decabromodiphenyl Ethane (DBDPE). | Sun Y, Wang X, Zhou S, Zhou Y, Hua J, Guo Y, Wang Y, Zhang W, Yang L, Zhou B | Environ Sci Technol |
| Identification of a DNA-cytosine methyltransferase that impacts global transcription to promote group B streptococcal vaginal colonization. | Manzer HS, Brunetti T, Doran KS | mBio |
| Increased academic stress is associated with decreased plasma BDNF in Chilean college students. | Castillo-Navarrete JL, Bustos C, Guzman-Castillo A, Vicente B | PeerJ |
| Aging and the impact of global DNA methylation, telomere shortening, and total oxidative status on sarcopenia and frailty syndrome. | Kmiołek T, Filipowicz G, Bogucka D, Wajda A, Ejma-Multański A, Stypińska B, Modzelewska E, Kaliberda Y, Radkowski M, Targowski T, Wrona J, Paradowska-Gorycka A | Immun Ageing |
| Studies in CRISPR-generated Mediterranean G6PD variant rats reveal G6PD orchestrates genome-wide DNA methylation and gene expression in vascular wall. | Signoretti C, Gupte SA | bioRxiv |
| Interactions between insulin resistance, epigenetics, and donor sex in gene expression regulation of iPSC-derived myoblasts. | Haider N, Kahn CR | J Clin Invest |
| Maternal betaine supplementation ameliorates fatty liver disease in offspring mice by inhibiting hepatic NLRP3 inflammasome activation. | Li L, Sun L, Liang X, Ou Q, Tan X, Li F, Lai Z, Ding C, Chen H, Yu X, Wu Q, Wei J, Wu F, Wang L | Nutr Res Pract |
| Association between SPRY1 and TET3 in skin photoaging and natural aging mechanisms. | Qiu B, Yang E, Zheng Y, Zhang H | J Cosmet Dermatol |
| Maternal exposure to E 551 during pregnancy leads to genome-wide DNA methylation changes and metabolic disorders in the livers of pregnant mice and their fetuses. | Zhan Y, Lou H, Shou R, Li A, Shang J, Jin Y, Li L, Zhu L, Lu X, Fan X | J Hazard Mater |
| Chemical tolerance related to the ABC transporter gene and DNA methylation in cladocera (Daphnia magna). | Ishimota M, Kodama M, Tomiyama N, Ohyama K | Environ Toxicol |
| Development and validation of a human bronchial epithelial spheroid model to study respiratory toxicity in vitro. | Celis T, Bullens DMA, Hoet PHM, Ghosh M | Arch Toxicol |
| Differential DNA methylation and metabolite profiling of Atlantic killifish (Fundulus heteroclitus) from the New Bedford Harbor Superfund site. | Kim J, Jung D, Chatterjee N, Clark B, Nacci D, Kim S, Choi J | Ecotoxicology |
| Disruption of DNA methylation-mediated cranial neural crest proliferation and differentiation causes orofacial clefts in mice. | Ulschmid CM, Sun MR, Jabbarpour CR, Steward AC, Rivera-González KS, Cao J, Martin AA, Barnes M, Wicklund L, Madrid A, Papale LA, Joseph DB, Vezina CM, Alisch RS, Lipinski RJ | Proc Natl Acad Sci U S A |
| Exogenous methionine contributes to reversing the resistance of Streptococcus suis to macrolides. | Dong C-L, Wu T, Dong Y, Qu Q-W, Chen X-Y, Li Y-H | Microbiol Spectr |
| Investigating the Effects of Valproic acid on Placental Epigenetic Modifications and Development in the CD-1 Mouse Model. | Jackson BL, Shafique S, Natale BV, Natale DRC, Winn LM | Reprod Toxicol |
| Biphasic regulation of epigenetic state by matrix stiffness during cell reprogramming. | Song Y, Soto J, Wong SY, Wu Y, Hoffman T, Akhtar N, Norris S, Chu J, Park H, Kelkhoff DO, Ang CE, Wernig M, Kasko A, Downing TL, Poo MM, Li S | Sci Adv |
| High estrogen during ovarian stimulation induced loss of maternal imprinted methylation that is essential for placental development via overexpression of TET2 in mouse oocytes. | Lu X, Mao J, Qian C, Lei H, Mu F, Sun H, Yan S, Fang Z, Lu J, Xu Q, Dong J, Su D, Wang J, Jin N, Chen S, Wang X | Cell Commun Signal |
| Tunable DNMT1 degradation reveals DNMT1/DNMT3B synergy in DNA methylation and genome organization. | Scelfo A, Barra V, Abdennur N, Spracklin G, Busato F, Salinas-Luypaert C, Bonaiti E, Velasco G, Bonhomme F, Chipont A, Tijhuis AE, Spierings DCJ, Guérin C, Arimondo P, Francastel C, Foijer F, Tost J, Mirny L, Fachinetti D | J Cell Biol |
| In Vitro Characterization of Reversine-Treated Gingival Fibroblasts and Their Safety Evaluation after In Vivo Transplantation. | Marto CM, Laranjo M, Gonçalves AC, Paula A, Jorge J, Caetano-Oliveira R, Sousa MI, Oliveiros B, Ramalho-Santos J, Sarmento-Ribeiro AB, Marques-Ferreira M, Cabrita A, Botelho MF, Carrilho E | Pharmaceutics |
| Early life adversity drives sex-dependent changes in 5-mC DNA methylation of parvalbumin cells in the prefrontal cortex in rats. | Noel ES, Chen A, Peña YA, Honeycutt JA | bioRxiv |
| The flame retardant triphenyl phosphate alters the epigenome of embryonic cells in an aquatic in vitro model. | Germain L, Winn LM | J Appl Toxicol |
| Ischemic preconditioning modulates the DNA methylation process of the rat heart to provide tolerance to withstand ischemia reperfusion injury and its associated mitochondrial dysfunction. | Boovarahan SR, Kurian GA | 3 Biotech |
| DNA methylation regulates the secondary metabolism of saponins to improve the adaptability of Eleutherococcus senticosus during drought stress. | Wang S, Zhao X, Li C, Dong J, Ma J, Long Y, Xing Z | BMC Genomics |
| Methylation of histone H3 lysine 36 is a barrier for therapeutic interventions of head and neck squamous cell carcinoma. | Caeiro LD, Nakata Y, Borges RL, Garcia-Martinez L, Bañuelos CP, Stransky S, Chan HL, Brabson J, DomÃnguez D, Zhang Y, Lewis PW, Aznar-Benitah S, Cimmino L, Bilbao D, Sidoli S, Verdun RE, Morey L | bioRxiv |
| Placental senescence pathophysiology is shared between peripartum cardiomyopathy and preeclampsia in mouse and human. | Roh JD, Castro C, Yu A, Rana S, Shahul S, Gray KJ, Honigberg MC, Ricke-Hoch M, Iwamoto Y, Yeri A, Kitchen R, Guerra JB, Hobson R, Chaudhari V, Chang B, Sarma A, Lerchenmüller C, Al Sayed ZR, Diaz Verdugo C, Xia P, Skarbianskis N, Zeisel A, Bauersachs J, Kirkland JL, Karumanchi SA, Gorcsan J 3rd, Sugahara M, Damp J, Hanley-Yanez K, | Sci Transl Med |
| Pre-eclamptic foetal programming predisposes offspring to hepatic steatosis via DNA methylation. | Chen H, Luo S, Deng X, Li S, Mao Y, Yan J, Cheng Y, Liu X, Pan J, Huang H | Biochim Biophys Acta Mol Basis Dis |
| Nitric oxide inhibits ten-eleven translocation DNA demethylases to regulate 5mC and 5hmC across the genome. | Thomas D, Palczewski M, Kuschman H, Hoffman B, Yang H, Glynn S, Wilson D, Kool E, Montfort W, Chang J, Petenkaya A, Chronis C, Cundari T, Sappa S, Islam K, McVicar D, Fan Y, Chen Q, Meerzaman D, Sierk M | Res Sq |
| Combining 5-azacitidine with the E-selectin antagonist uproleselan is an effective strategy to augment responses in myelodysplasia and acute myeloid leukaemia. | Enjeti AK, Fogler WE, Smith TAG, Lincz LF, Bond DR, Magnani JL | Br J Haematol |
| Expression of genes related to gonadal development and construction of gonadal DNA methylation maps of Trachinotus blochii under hypoxia. | Gu Y, Jin CX, Tong ZH, Jiang T, Yao FC, Zhang Y, Huang J, Song FB, Sun JL, Luo J | Sci Total Environ |
| Phosphorylated SHMT2 Regulates Oncogenesis Through m(6)A Modification in Lung Adenocarcinoma. | Han T, Wang Y, Cheng M, Hu Q, Wan X, Huang M, Liu Y, Xun W, Xu J, Wang L, Luo R, Yuan Y, Wang K, Wang J | Adv Sci (Weinh) |
| Biomarkers of Depression among Adolescent Girls: BDNF and Epigenetics. | Zwolińska W, Bilska K, Tarhonska K, Reszka E, Skibińska M, Pytlińska N, Słopień A, Dmitrzak-Węglarz M | Int J Mol Sci |
| A role of epigenetic mechanisms in regulating female reproductive responses to temperature in a pest beetle. | McCaw BA, Leonard AM, Stevenson TJ, Lancaster LT | Insect Mol Biol |
| Pirfenidone Reverts Global DNA Hypomethylation, Promoting DNMT1/UHRF/PCNA Coupling Complex in Experimental Hepatocarcinoma. | Miranda-Roblero HO, Saavedra-Salazar LF, Galicia-Moreno M, Arceo-Orozco S, Caloca-Camarena F, Sandoval-Rodriguez A, GarcÃa-Bañuelos J, Frias-Gonzalez C, Almeida-López M, MartÃnez-López E, Armendariz-Borunda J, Monroy-Ramirez HC | Cells |
| Electromagnetic field-induced adaptive response in Schwann cells through DNA methylation, histone deacetylation, and oxidative stress. | Colciago A, Mohamed T, Colleoni D, Melfi V, Magnaghi V | J Cell Physiol |
| DNMT3A dysfunction promotes neuroinflammation and exacerbates acute ischemic stroke. | Lyu TJ, Qiu X, Wang Y, Zhang L, Dai Y, Wang X, Zhao S, Xiang M, Cui L, Cheng S, Liu Y, Gu H, Jiang Y, Meng X, Wang Y, Zhao X, Wang X, Li Q, Wang M, Jiang Y, Xu Z, Huang X, Li H, Wang Y, Li Z | MedComm (2020) |
| Combined Exercise and Diet Induce Airway Hyperreactivity While Reducing Liver Steatosis in Mice with Diet-Induced Obesity. | Marain NF, Jonckheere AC, Dilissen E, Cremer J, Roskams T, Colemont M, Bullens DM, Dupont LJ, Vanoirbeek JA | Nutrients |
| Global DNA and RNA Methylation Signature in Response to Antipsychotic Treatment in First-Episode Schizophrenia Patients. | Angelin M, Gopinath P, Raghavan V, Thara R, Ahmad F, Munirajan AK, Sudesh R | Neuropsychiatr Dis Treat |
| Carryover effects of embryonic hypoxia exposure on adult fitness of the Pacific abalone. | Dai Y, Shen Y, Ke C, Luo X, Huang M, Huang H, You W | Environ Res |
| Decoding the Epigenetic Landscape: Insights into 5mC and 5hmC Patterns in Mouse Cortical Cell Types. | Wei X, Li J, Cheng Z, Wei S, Yu G, Olsen ML | bioRxiv |
| Translocating bacteria in SIV infection are not stochastic and preferentially express cytosine methyltransferases. | Flynn JK, Ortiz AM, Vujkovic-Cvijin I, Welles HC, Simpson J, Castello Casta FM, Yee DS, Rahmberg AR, Brooks KL, De Leon M, Knodel S, Birse K, Noel-Romas L, Deewan A, Belkaid Y, Burgener A, Brenchley JM | Mucosal Immunol |
| miR-93-5p impairs autophagy-lysosomal pathway via TET3 after subarachnoid hemorrhage. | Ding PF, Liu XZ, Peng Z, Cui Y, Liu Y, Zhang JT, Zhu Q, Wang J, Zhou Y, Gao YY, Hang CH, Li W | Exp Neurol |
| Essential Oils from Southern Italian Aromatic Plants Synergize with Antibiotics against Escherichia coli, Pseudomonas aeruginosa and Enterococcus faecalis Cell Growth and Biofilm Formation. | Sena G, De Rose E, Crudo M, Filippelli G, Passarino G, Bellizzi D, D'Aquila P | Antibiotics (Basel) |
| A short-term exposure to saxitoxin triggers a multitude of deleterious effects in Daphnia magna at levels deemed safe for human health. | Pinto A, Macário IPE, Marques SM, Lourenço J, Domingues I, Botelho MJ, Asselman J, Pereira P, Pereira JL | Sci Total Environ |
| Inflammation-induced epigenetic imprinting regulates intestinal stem cells. | Zhao D, Ravikumar V, Leach TJ, Kraushaar D, Lauder E, Li L, Sun Y, Oravecz-Wilson K, Keller ET, Chen F, Maneix L, Jenq RR, Britton R, King KY, Santibanez AE, Creighton CJ, Rao A, Reddy P | Cell Stem Cell |
| Genome-wide DNA methylation sequencing reveals the involvement of ferroptosis in hepatotoxicity induced by dietary exposure to food-grade titanium dioxide. | Shang J, Yan J, Lou H, Shou R, Zhan Y, Lu X, Fan X | Part Fibre Toxicol |
| Glutaminase inhibition in combination with azacytidine in myelodysplastic syndromes: a phase 1b/2 clinical trial and correlative analyses. | DiNardo CD, Verma D, Baran N, Bhagat TD, Skwarska A, Lodi A, Saxena K, Cai T, Su X, Guerra VA, Poigaialwar G, Kuruvilla VM, Konoplev S, Gordon-Mitchell S, Pradhan K, Aluri S, Hackman GL, Chaudhry S, Collins M, Sweeney SR, Busquets J, Rathore AS, Deng Q, Green MR, Grant S, Demo S, Choudhary GS, Sahu S, Agarwal B, Spodek M, Thiruthuv | Nat Cancer |
| Assessment of Diagnostic Accuracy and Clinical Utility of DNA Methylation (5-mC) in Detecting Severity of Occupational Lead Exposure. | Kalahasthi R, Adepu VK, Nagaraju R | Indian J Clin Biochem |
| Pathophysiologic effects of waterpipe (shisha) smoke inhalation on liver morphology and function in mice. | Nemmar A, Beegam S, Yuvaraju P, Zaaba NE, Elzaki O, Yasin J, Adeghate E | Life Sci |
| Hypertension and global DNA methylation: a population-based study in rural, Punjab, India. | Kaushik A, Bhattacharjee D, Chaudhary V, Dahal S, Devi NK, Mitra RP, Dhamija RK, Krishan K, Pandey R, Saraswathy KN | Sci Rep |
| Genome-wide DNA methylation regulated by AHCY through SAM / SAH axis promotes psoriasis pathogenesis. | Liu L, Chen L, Hu Y, Zhang Q, Chen K, Zhang J | J Dermatol Sci |
| Placental expression and methylation of angiogenic factors in assisted reproductive technology pregnancies from India. | Sundrani D, Kapare A, Yadav H, Randhir K, Gupte S, Joshi S | Epigenomics |
| DNMT3a Deficiency Contributes to Anesthesia/Surgery-Induced Synaptic Dysfunction and Cognitive Impairment in Aged Mice. | Cong P, Huang X, Zhang Q, He M, Wan H, Wu Q, Wu H, Zhang Y, Cheng C, Tian L, Xiong L | Aging Cell |
| Assessing molecular changes underlying isopropylated phenyl phosphate (IPP)-induced larval sensorimotor response deficits in zebrafish. | Sharma S, Rojas A, Gour A, Serradimigni R, Leong C, Sharma A, Dasgupta S | Ecotoxicol Environ Saf |
| Dnmt3a-mediated DNA Methylation Regulates P. gingivalis-suppressed Cementoblast Mineralization Partially Via Mitochondria-dependent Apoptosis Pathway. | Liu H, Ma L, Wang H, Huang X, Peng Y, Yang Z, Xiao J, Huang H, Yang Q, Sun J, Wang X, Wang C, Yang L, Cao Z | Inflammation |
