DNA topoisomerases I and II (top1 and top2, respectively) are ubiquitous enzymes t...
生物知识
生物知识
生物知识
Induction of Tumor Cell Apoptosis by TRAIL Gene Therapy
Members of the tumor necrosis factor (TNF) superfamily influence a variety of immu...
生物知识
WT-1 Overexpression in Acute Myeloid Leukemia and Myelodysplastic Syndromes
The Wilms tumor gene was identified as a tumor suppressor gene responsible for a p...
生物知识
Isolation of Melanoma Cell Subpopulations Using Negative Selection
Melanomas are phenotypically and functionally heterogeneous tumors comprising of d...
生物知识
Identification of Mutations in the Retinoblastoma Gene
Mutations in the retinoblastoma gene (RBl) predispose to the formation of ocular t...
生物知识
Different Study Designs in the Epidemiology of Cancer: Case-Control vs. Cohort Studies
It is only since the 1950s that most of the epidemiology studies on cancer have be...
生物知识
Molecular Genetic Analysis of Flow-Sorted and Microdissected Ovarian Tumor Cells Improved Detection
Study of loss of heterozygosity (LOH) is widely used to identify chromosomal locat...
生物知识
Detecting and Modulating the NF-kB Activity in Human Immune Cells: Generation of Human Cell Lines wi
NF-κB plays a pivotal role in immunity and inflammation and is considered to be a ...
生物知识
Chemopreventive Therapeutics: Inhalation Therapies for Lung Cancer and Bronchial Premalignancy
Lung cancer is the number one cause of cancer-related death in the US. In 2001, it...
生物知识
Gene Therapy in Melanoma
The identification of genes involved in different biologic functions and in the pa...
