Many types of human leukemias and lymphomas are associated with specific chromosom...

The invasion and metastasis of tumor cells has been shown to require proteolytic a...

Nuclear factor kappa B (NF-κB) is an inducible transcription factor that regulates...

Genetic instability is a hallmark of human cancers. It is the driving force for tu...

Chemotherapy induces injury to tumor cells, which subsequently die by a number of ...

Gliomas account for more than 70% of all brain tumors, and of these, glioblastoma ...

Mammalian CHK1 is a Ser/Thr effector kinase that plays critical roles in the DNA d...

Modulation of P-glycoprotein (Pgp)-mediated transport has significant pharmacokine...

Identification of hereditary factors that predispose to cancer allows targeted can...

Alterations of protein tyrosine kinase and tyrosine phosphatase are often associat...