生物知识 In Vitro Selection of Metal Ion-Selective DNAzymes The discovery of DNAzymes that can catalyze a wide range of reactions in the prese... 04月17日 发表评论 阅读全文
生物知识 A screen to identify drug resistant variants to target-directed anti-cancer agents The discovery of oncogenes and signal transduction pathways important for mitogene... 04月17日 发表评论 阅读全文
生物知识 The Use of Restriction Endonucleases The discovery of the mode of action of the class of bacterial enzymes known as res... 04月17日 发表评论 阅读全文
生物知识 Saturation-Recovery Electron Paramagnetic Resonance Discrimination by Oxygen Transport (DOT) Method The discrimination by oxygen transport (DOT) method is a dual-probe saturation-rec... 04月17日 发表评论 阅读全文
生物知识 A Non-covalent Peptide-Based Strategy for Ex Vivo and In Vivo Oligonucleotide Delivery The dramatic acceleration in identification of new nucleic acid-based therapeutic ... 04月17日 发表评论 阅读全文
生物知识 Practical Considerations of Image Analysis and Quantification of Signal Transduction IHC Staining The dramatic increase in computer processing power in combination with the availab... 04月17日 发表评论 阅读全文
生物知识 Determining Allosteric Modulator Mechanism of Action: Integration of Radioligand Binding and Functio The drive to produce safer and more receptor subtype selective drugs has sparked a... 04月17日 发表评论 阅读全文
生物知识 Enzymatic Characterization of Recombinant Enzymes of O-GlcNAc Cycling The dynamic addition ofO-GlcNAc to target proteins is now recognized as a major si... 04月17日 发表评论 阅读全文
生物知识 Synthesis, Mass Spectrometric Characterization, and Analysis of the PPAR Agonist GW1516 and Its Majo The elucidation of metabolic pathways and the detection of emerging therapeutics p... 04月17日 发表评论 阅读全文
生物知识 Application of Dual Cyclodextrin Systems in Capillary Electrophoresis Enantioseparations The enantioseparation of acidic and neutral compounds can be successfully achieved... 04月17日 发表评论 阅读全文