TentaGel®树脂是由低交联聚苯乙烯基质组成的接枝共聚物，聚乙二醇（PEG或POE）通过乙醚基团接枝在该基质上，从而提高对酸处理的稳定性并最大限度地减少PEG浸出。 该接枝共聚物显示出改性的物理化学性质，这些性质由PEG部分（不再由聚苯乙烯基质）高度主导，并且具有疏水性和亲水性。 这些共聚物是压力稳定的，可以用于间歇工艺以及在连续流动条件下。 PEG间隔基的分子量在3000 Da范围内。TentaGel®树脂在从甲苯到水的各种溶剂中具有高扩散速率和优异的溶胀性。
TentaGel®树脂：一种用于亲核试剂固定化的活性酯树脂。
| 产品名称 | 货号 | 规格 |
| TentaGel® S NHS Ester | S30135.1G | 130 µm |
| TentaGel® S NH-NH-Boc | S30137.1G | 130 µm |
| TentaGel® S NHS Ester | S30905.1G | 90 µm |
| TentaGel® S NH-NH-Boc | S30907.1G | 90 µm |
数百篇文献:
- Bayer, E.; Albert, K.; Willisch, H.; Rapp, W.; Hemmasi, B. Carbon-13 NMR Relaxation Times of a Tripeptide Methyl Ester and Its Polymer-Bound Analogs. Macromolecules 1990, 23 (7), 1937-1940. doi: 10.1021/ma00209a010.
- Rudinger J., Buetzer P. in Peptides 1974 (Wolman J., Ed.), Wiley, New York, (1975), 211.
- Bayer E., Rapp W. Polystyrene-Immobilized PEG Chains Dynamics and Applications in Poly(Ethylene Glycol) Chemistry: Biotechnical and Biomedical Application, (Harris M., Ed.) Plenum Press, New York, (1992), 325.
- Zhang L., Rapp W., Bayer E. Continuous flow peptide synthesis: Dependence of the kinetics upon the nature of polymeric support, method of activation and reaction conditions in Peptides 1990, Proceedings of the 21st European Peptide Symposium (Giralt E., Andreus D., Eds.) Escom Leiden, (1991), 196.
- Rapp W. Prevention of side reactions by high speed continuous flow peptide synthesis in Peptides 1992, Proceedings of the 22th European Peptide Symposium (Schneider C. H., Eberle A.N., Eds.) Escom Leiden, (1993), 243.
- Shemyakin, M. M.; Ovchinnikov, Y. A.; Kinyushkin, A. A.; Kozhevnikova, I. V. Synthesis of Peptides in Solution on a Polymeric Support I. Synthesis of Glycylglycyl-l-Leucylglycine. Tetrahedron Lett. 1965, 6 (27), 2323-2327. doi: 10.1016/s0040-4039(00)70379-0.
- Andreatta, R. H.; Rink, H. Zur Problematik der Peptidsynthese an Trägern: Beitrag eines neuen Verfahrens mit löslichen Trägern. Helv. Chim. Acta 1973, 56 (4), 1205-1218. doi: 10.1002/hlca.19730560405.
