Development of ovarian cancer is known to be associated with alterations in the expression of cellular RNAs. Most of the clinical and biological characteristics of ovarian cancer have been correlated with significant changes in the expression of a subset of genes. Over the last few years, considerable resources have been focused on understanding the complex structure and function of noncoding RNAs, and this paradigm is also applicable to ovarian cancer research. The chapter provides a brief review of methodological approaches used to study alterations in protein coding and noncoding RNAs in the context of ovarian cancer.
