MethylFlash™ 甲基化 DNA 定量试剂盒（比色法）通过简化工作流程和提高结果的一致性，进一步改进了我们之前的 Methylamp™ 整体 DNA 甲基化定量试剂盒。它使用一种创新方法使背景信号极低，从而消除了板的干燥和阻塞步骤。与基于色谱的方法（如 HPLC 或质谱法）相比，该产品提供了一种经济高效的方法来准确测量 5-甲基胞嘧啶的水平。
| 产品名称 | 货号 | 应用 |
| MethylFlash 甲基化 DNA 5-mC 定量试剂盒（比色） MethylFlash Methylated DNA 5-mC Quantification Kit (Colorimetric) |
P-1034-48 P-1034-96 |
测量 5-甲基胞嘧啶的水平 |
| MethylFlash 羟甲基化 DNA 5-hmC 定量试剂盒（比色） | P-1036-48 | 定量甲基化 DNA 和羟甲基化 DNA |
该MethylFlash 甲基化 DNA 5-mC 定量试剂盒（比色）还经过专门优化，可与 MethylFlash 羟甲基化 DNA 5-hmC 定量试剂盒（比色） 配合使用，同时定量甲基化 DNA 和羟甲基化 DNA。
产品特点
MethylFlash™ 甲基化 DNA 定量试剂盒（比色法）具有以下优点和特点：
- 比色分析具有易于遵循的步骤，方便快捷。整个过程可以在 4 小时内完成。
- 创新的试剂盒组成使背景信号极低，无需板封闭，使检测简单、准确、可靠且一致。
- 高灵敏度，其中检测限可低至 0.2 ng 的甲基化 DNA，可接受低至 50 ng 的起始基因组 DNA。
- 优化的抗体和增强剂溶液对 5mC 具有高度特异性，在样品 DNA 的指定浓度范围内，与未甲基化胞嘧啶没有交叉反应性，与羟甲基胞嘧啶没有或可以忽略不计的交叉反应性。
- 包括通用阳性和阴性对照，适用于定量任何物种的甲基化 DNA。
- 联管孔板规格使分析更加灵活：手动或高通量分析。
已发表文献466篇：
| 文献标题 | 作者 | 杂志名称 |
| Association of Global DNA Methylation and Global DNA Hydroxymethylation with Metals and other Exposures in Human Blood DNA Samples. | Tellez-Plaza M, Tang WY, Shang Y, Umans JG, Francesconi KA, Goessler W, Ledesma M, Leon M, Laclaustra M, Pollak J, Guallar E, Cole SA, Fallin MD, Navas-Acien A | Environ Health Perspect |
| Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 promotes cell proliferation and migration by upregulating DNMT1 via STAT3 activation. | Wu J, Xu Y, Mo D, Huang P, Sun R, Huang L, Pan S, Xu J | PLoS One |
| Epigenetic Signature of Chronic Cerebral Hypoperfusion and Beneficial Effects of S-adenosylmethionine in Rats. | Wu X, Sun J, Zhang X, Li X, Liu Z, Yang Q, Li L | Mol Neurobiol |
| The CpG Island Encompassing the Promoter and First Exon of Human DNMT3L Gene Is a PcG/TrX Response Element (PRE). | Basu A, Dasari V, Mishra RK, Khosla S | PLoS One |
| Gene expression signatures affected by alcohol-induced DNA methylomic deregulation in human embryonic stem cells. | Khalid O, Kim JJ, Kim HS, Hoang M, Tu TG, Elie O, Lee C, Vu C, Horvath S, Spigelman I, Kim Y | Stem Cell Res |
| Distribution of 5-hydroxymethylcytosine in different human tissues. | Li W, Liu M | J Nucleic Acids |
| Aberrant methylation of Polo-like kinase CpG islands in Plk4 heterozygous mice. | Ward A, Morettin A, Shum D, Hudson JW | BMC Cancer |
| Promoter de-methylation of cyclin D2 by sulforaphane in prostate cancer cells. | Hsu A, Wong CP, Yu Z, Williams DE, Dashwood RH, Ho E | Clin Epigenetics |
| Human dedifferentiated adipocytes show similar properties to bone marrow-derived mesenchymal stem cells. | Poloni A, Maurizi G, Leoni P, Serrani F, Mancini S, Frontini A, Zingaretti MC, Siquini W, Sarzani R, Cinti S | Stem Cells |
| Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus. | Chen H, Dzitoyeva S, Manev H | Restor Neurol Neurosci |
| Epigenetic alterations may regulate temporary reversal of CD4(+) T cell activation caused by trichloroethylene exposure. | Gilbert KM, Nelson AR, Cooney CA, Reisfeld B, Blossom SJ | Toxicol Sci |
| Hiwi mediated tumorigenesis is associated with DNA hypermethylation. | Siddiqi S, Terry M, Matushansky I | PLoS One |
| DNA demethylating agent decitabine increases AQP5 expression and restores salivary function. | Yamamura Y, Aota K, Yamanoi T, Kani K, Takano H, Momota Y, Motegi K, Azuma M | J Dent Res |
| Oxidative DNA damage and global DNA hypomethylation are related to folate deficiency in chromate manufacturing workers. | Wang TC, Song YS, Wang H, Zhang J, Yu SF, Gu YE, Chen T, Wang Y, Shen HQ, Jia G | J Hazard Mater |
| Vitamin B12 deficiency in the brain leads to DNA hypomethylation in the TCblR/CD320 knockout mouse. | Fernàndez-Roig S, Lai SC, Murphy MM, Fernandez-Ballart J, Quadros EV | Nutr Metab (Lond) |
| Methionine restriction affects the phenotypic and transcriptional response of rainbow trout (Oncorhynchus mykiss) to carbohydrate-enriched diets. | Craig PM, Moon TW | Br J Nutr |
| Prostaglandin Eâ‚‚ increases fibroblast gene-specific and global DNA methylation via increased DNA methyltransferase expression. | Huang SK, Scruggs AM, Donaghy J, McEachin RC, Fisher AS, Richardson BC, Peters-Golden M | FASEB J |
| Male germline transmits fetal alcohol adverse effect on hypothalamic proopiomelanocortin gene across generations. | Govorko D, Bekdash RA, Zhang C, Sarkar DK | Biol Psychiatry |
| Long-term nonprogressor and elite controller patients who control viremia have a higher percentage of methylation in their HIV-1 proviral promoters than aviremic patients receiving highly active antiretroviral therapy. | Palacios JA, Pérez-Piñar T, Toro C, Sanz-Minguela B, Moreno V, Valencia E, Gómez-Hernando C, Rodés B | J Virol |
| Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease. | Arakawa Y, Watanabe M, Inoue N, Sarumaru M, Hidaka Y, Iwatani Y | Clin Exp Immunol |
| Ethnic differences in DNA methyltransferases expression in patients with systemic lupus erythematosus. | Wiley KL, Treadwell E, Manigaba K, Word B, Lyn-Cook BD | J Clin Immunol |
| Genetic variation in DNMT3B and increased global DNA methylation is associated with suicide attempts in psychiatric patients. | Murphy TM, Mullins N, Ryan M, Foster T, Kelly C, McClelland R, O'Grady J, Corcoran E, Brady J, Reilly M, Jeffers A, Brown K, Maher A, Bannan N, Casement A, Lynch D, Bolger S, Buckley A, Quinlivan L, Daly L, Kelleher C, Malone KM | Genes Brain Behav |
| Perinatal nicotine exposure induces asthma in second generation offspring. | Rehan VK, Liu J, Naeem E, Tian J, Sakurai R, Kwong K, Akbari O, Torday JS | BMC Med |
| Associations between aberrant DNA methylation and transcript levels of DNMT1 and MBD2 in CD4+T cells from patients with systemic lupus erythematosus. | Qin HH, Zhu XH, Liang J, Yang YS, Wang SS, Shi WM, Xu JH | Australas J Dermatol |
| Molecular cloning, tissue expression, and analysis with genome DNA methylation of porcine LSD1 gene. | Chai J, Liu L, Xiong Q, Chen C, Peng Y, Jin W, Zheng R, Peng J, Jiang S | Appl Biochem Biotechnol |
| The 5-methyl-deoxy-cytidine (5mdC) localization to reveal in situ the dynamics of DNA methylation chromatin pattern in a variety of plant organ and tissue cells during development. | Testillano PS, Solís MT, Risueño MC | Physiol Plant |
| Cigarette smoke condensate induces differential expression and promoter methylation profiles of critical genes involved in lung cancer in NL-20 lung cells in vitro: short-term and chronic exposure. | Word B, Lyn-Cook LE Jr, Mwamba B, Wang H, Lyn-Cook B, Hammons G | Int J Toxicol |
| Methylome profiling reveals distinct alterations in phenotypic and mutational subgroups of myeloproliferative neoplasms. | Nischal S, Bhattacharyya S, Christopeit M, Yu Y, Zhou L, Bhagat TD, Sohal D, Will B, Mo Y, Suzuki M, Pardanani A, McDevitt M, Maciejewski JP, Melnick AM, Greally JM, Steidl U, Moliterno A, Verma A | Cancer Res |
| Effects of paternal folate deficiency on the expression of insulin-like growth factor-2 and global DNA methylation in the fetal brain. | Kim HW, Kim KN, Choi YJ, Chang N | Mol Nutr Food Res |
| Inherited effects of low-dose exposure to methylmercury in neural stem cells. | Bose R, Onishchenko N, Edoff K, Janson Lang AM, Ceccatelli S | Toxicol Sci |
| Identification of epigenetically altered genes in sporadic amyotrophic lateral sclerosis. | Figueroa-Romero C, Hur J, Bender DE, Delaney CE, Cataldo MD, Smith AL, Yung R, Ruden DM, Callaghan BC, Feldman EL | PLoS One |
| MicroRNA-29b contributes to DNA hypomethylation of CD4+ T cells in systemic lupus erythematosus by indirectly targeting DNA methyltransferase 1. | Qin H, Zhu X, Liang J, Wu J, Yang Y, Wang S, Shi W, Xu J | J Dermatol Sci |
| Nanotopographical cues augment mesenchymal differentiation of human embryonic stem cells. | Kingham E, White K, Gadegaard N, Dalby MJ, Oreffo RO | Small |
| Impact of global and gene-specific DNA methylation pattern in relapsed multiple myeloma patients treated with bortezomib. | Fernández de Larrea C, Martín-Antonio B, Cibeira MT, Navarro A, Tovar N, Díaz T, Rosiñol L, Monzó M, Urbano-Ispizua A, Bladé J | Leuk Res |
| Alcohol modulates expression of DNA methyltranferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts. | Mukhopadhyay P, Rezzoug F, Kaikaus J, Greene RM, Pisano MM | Reprod Toxicol |
| Lifelong exposure to bisphenol a alters cardiac structure/function, protein expression, and DNA methylation in adult mice. | Patel BB, Raad M, Sebag IA, Chalifour LE | Toxicol Sci |
| Maternal diet supplemented with methyl-donors protects against atherosclerosis in F1 ApoE(-/-) mice. | Delaney C, Garg SK, Fernandes C, Hoeltzel M, Allen RH, Stabler S, Yung R | PLoS One |
| Sirtuin-6-dependent genetic and epigenetic alterations are associated with poor clinical outcome in hepatocellular carcinoma patients. | Marquardt JU, Fischer K, Baus K, Kashyap A, Ma S, Krupp M, Linke M, Teufel A, Zechner U, Strand D, Thorgeirsson SS, Galle PR, Strand S | Hepatology |
| Epigenetic alterations by DNA methylation in house dust mite-induced airway hyperresponsiveness. | Shang Y, Das S, Rabold R, Sham JS, Mitzner W, Tang WY | Am J Respir Cell Mol Biol |
| Soluble oligomers of amyloid-β cause changes in redox state, DNA methylation, and gene transcription by inhibiting EAAT3 mediated cysteine uptake. | Hodgson N, Trivedi M, Muratore C, Li S, Deth R | J Alzheimers Dis |
| Metabolic changes and DNA hypomethylation in cerebellum are associated with behavioral alterations in mice exposed to trichloroethylene postnatally. | Blossom SJ, Cooney CA, Melnyk SB, Rau JL, Swearingen CJ, Wessinger WD | Toxicol Appl Pharmacol |
| Changes in the epigenetic status of the SOX-9 promoter in human osteoarthritic cartilage. | Kim KI, Park YS, Im GI | J Bone Miner Res |
| Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels. | Jenkins TG, Aston KI, Cairns BR, Carrell DT | Fertil Steril |
| Status epilepticus triggers early and late alterations in brain-derived neurotrophic factor and NMDA glutamate receptor Grin2b DNA methylation levels in the hippocampus. | Ryley Parrish R, Albertson AJ, Buckingham SC, Hablitz JJ, Mascia KL, Davis Haselden W, Lubin FD | Neuroscience |
| Chronic cerebrovascular hypoperfusion affects global DNA methylation and histone acetylation in rat brain. | Wu X, Sun J, Li L | Neurosci Bull |
| The catalytic subunit of protein phosphatase 2A (PP2Ac) promotes DNA hypomethylation by suppressing the phosphorylated mitogen-activated protein kinase/extracellular signal-regulated kinase (ERK) kinase (MEK)/phosphorylated ERK/DNMT1 protein pathway in T-cells from controls and systemic lupus erythematosus patients. | Sunahori K, Nagpal K, Hedrich CM, Mizui M, Fitzgerald LM, Tsokos GC | J Biol Chem |
| Decreased survival in normal karyotype AML with single-nucleotide polymorphisms in genes encoding the AraC metabolizing enzymes cytidine deaminase and 5'-nucleotidase. | Falk IJ, Fyrberg A, Paul E, Nahi H, Hermanson M, Rosenquist R, Höglund M, Palmqvist L, Stockelberg D, Wei Y, Gréen H, Lotfi K | Am J Hematol |
| Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. | Williams-Karnesky RL, Sandau US, Lusardi TA, Lytle NK, Farrell JM, Pritchard EM, Kaplan DL, Boison D | J Clin Invest |
| Role of DNA methylation in cell cycle arrest induced by Cr (VI) in two cell lines. | Lou J, Wang Y, Yao C, Jin L, Wang X, Xiao Y, Wu N, Song P, Song Y, Tan Y, Gao M, Liu K, Zhang X | PLoS One |
| Novel synthetic curcumin analogues EF31 and UBS109 are potent DNA hypomethylating agents in pancreatic cancer. | Nagaraju GP, Zhu S, Wen J, Farris AB, Adsay VN, Diaz R, Snyder JP, Mamoru S, El-Rayes BF | Cancer Lett |
| DNA methylation markers in the postnatal developing rat brain. | Simmons RK, Stringfellow SA, Glover ME, Wagle AA, Clinton SM | Brain Res |
| Effects of parental folate deficiency on the folate content, global DNA methylation, and expressions of FRa, IGF-2 and IGF-1R in the postnatal rat liver. | Mejos KK, Kim HW, Lim EM, Chang N | Nutr Res Pract |
| Perinatal bisphenol A exposures increase production of pro-inflammatory mediators in bone marrow-derived mast cells of adult mice. | O'Brien E, Dolinoy DC, Mancuso P | J Immunotoxicol |
| Global and gene specific DNA methylation changes during zebrafish development. | Fang X, Corrales J, Thornton C, Scheffler BE, Willett KL | Comp Biochem Physiol B Biochem Mol Biol |
| Unique anti-glioblastoma activities of hypericin are at the crossroad of biochemical and epigenetic events and culminate in tumor cell differentiation. | Dror N, Mandel M, Lavie G | PLoS One |
| Sodium fluoride disrupts DNA methylation of H19 and Peg3 imprinted genes during the early development of mouse embryo. | Zhu JQ, Si YJ, Cheng LY, Xu BZ, Wang QW, Zhang X, Wang H, Liu ZP | Arch Toxicol |
| Epigenetic changes in the progression of Alzheimer's disease. | Bradley-Whitman MA, Lovell MA | Mech Ageing Dev |
| Effects of chromatin decondensation on alternative NHEJ. | Moscariello M, Iliakis G | DNA Repair (Amst) |
| Dynamic changes in DNA methylation and hydroxymethylation when hES cells undergo differentiation toward a neuronal lineage. | Kim M, Park YK, Kang TW, Lee SH, Rhee YH, Park JL, Kim HJ, Lee D, Lee D, Kim SY, Kim YS | Hum Mol Genet |
| Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice. | Moldrich RX, Leanage G, She D, Dolan-Evans E, Nelson M, Reza N, Reutens DC | Behav Brain Res |
| Aberrant epigenetic modification in murine brain tissues of offspring from preimplantation genetic diagnosis blastomere biopsies. | Zhao HC, Zhao Y, Li M, Yan J, Li L, Li R, Liu P, Yu Y, Qiao J | Biol Reprod |
| Methylenetetrahydrofolate reductase C677T and methionine synthase A2756G polymorphisms influence on leukocyte genomic DNA methylation level. | Weiner AS, Boyarskikh UA, Voronina EN, Mishukova OV, Filipenko ML | Gene |
| Cytokine induced phenotypic and epigenetic signatures are key to establishing specific macrophage phenotypes. | Kittan NA, Allen RM, Dhaliwal A, Cavassani KA, Schaller M, Gallagher KA, Carson WF 4th, Mukherjee S, Grembecka J, Cierpicki T, Jarai G, Westwick J, Kunkel SL, Hogaboam CM | PLoS One |
| Evidence that active demethylation mechanisms maintain the genome of carcinoma in situ cells hypomethylated in the adult testis. | Kristensen DG, Nielsen JE, Jørgensen A, Skakkebæk NE, Rajpert-De Meyts E, Almstrup K | Br J Cancer |
| Analysis of TET expression/activity and 5mC oxidation during normal and malignant germ cell development. | Nettersheim D, Heukamp LC, Fronhoffs F, Grewe MJ, Haas N, Waha A, Honecker F, Waha A, Kristiansen G, Schorle H | PLoS One |
| Probing for DNA methylation with a voltammetric DNA detector. | Saheb A, Patterson S, Josowicz M | Analyst |
| Association of microRNA-31 with BRAF mutation, colorectal cancer survival and serrated pathway. | Nosho K, Igarashi H, Nojima M, Ito M, Maruyama R, Yoshii S, Naito T, Sukawa Y, Mikami M, Sumioka W, Yamamoto E, Kurokawa S, Adachi Y, Takahashi H, Okuda H, Kusumi T, Hosokawa M, Fujita M, Hasegawa T, Okita K, Hirata K, Suzuki H, Yamamoto H, Shinomura Y | Carcinogenesis |
| DNA demethylation enhances myoblasts hypertrophy during the late phase of myogenesis activating the IGF-I pathway. | Senesi P, Luzi L, Montesano A, Terruzzi I | Endocrine |
| Characterization of non-CG genomic hypomethylation associated with gamma-ray-induced suppression of CMT3 transcription in Arabidopsis thaliana. | Kim JE, Lee MH, Cho EJ, Kim JH, Chung BY, Kim JH | Radiat Res |
| Alternative splicing, promoter methylation, and functional SNPs of sperm flagella 2 gene in testis and mature spermatozoa of Holstein bulls. | Guo F, Yang B, Ju ZH, Wang XG, Qi C, Zhang Y, Wang CF, Liu HD, Feng MY, Chen Y, Xu YX, Zhong JF, Huang JM | Reproduction |
| Embryonic caffeine exposure acts via A1 adenosine receptors to alter adult cardiac function and DNA methylation in mice. | Buscariollo DL, Fang X, Greenwood V, Xue H, Rivkees SA, Wendler CC | PLoS One |
| p53-Dependent and cell specific epigenetic regulation of the polo-like kinases under oxidative stress. | Ward A, Hudson JW | PLoS One |
| DNA methylation and regulation of the CD8A after duck hepatitis virus type 1 infection. | Xu Q, Chen Y, Zhao WM, Huang ZY, Zhang Y, Li X, Tong YY, Chang GB, Duan XJ, Chen GH | PLoS One |
| Learning induced epigenetic modifications in the ventral striatum are necessary for long-term memory. | Gaglio D, Capitano F, Mastrodonato A, Minicocci E, Deiana C, Fragapane P, Camilloni G, Mele A | Behav Brain Res |
| Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate. | Saldanha SN, Kala R, Tollefsbol TO | Exp Cell Res |
| Betaine attenuates hepatic steatosis by reducing methylation of the MTTP promoter and elevating genomic methylation in mice fed a high-fat diet. | Wang LJ, Zhang HW, Zhou JY, Liu Y, Yang Y, Chen XL, Zhu CH, Zheng RD, Ling WH, Zhu HL | J Nutr Biochem |
| Circadian behavior is light-reprogrammed by plastic DNA methylation. | Azzi A, Dallmann R, Casserly A, Rehrauer H, Patrignani A, Maier B, Kramer A, Brown SA | Nat Neurosci |
| Dose- and time-dependent epigenetic changes in the livers of fisher 344 rats exposed to furan. | Conti Ad, Kobets T, Escudero-Lourdes C, Montgomery B, Tryndyak V, Beland FA, Doerge DR, Pogribny IP | Toxicol Sci |
| Epigenetic modification of Nrf2 in 5-fluorouracil-resistant colon cancer cells: involvement of TET-dependent DNA demethylation. | Kang KA, Piao MJ, Kim KC, Kang HK, Chang WY, Park IC, Keum YS, Surh YJ, Hyun JW | Cell Death Dis |
| Repetitive genomic elements and overall DNA methylation changes in acute myeloid and childhood B-cell lymphoblastic leukemia patients. | Bujko M, Musialik E, Olbromski R, Przestrzelska M, Libura M, Pastwińska A, Juszczyński P, Zwierzchowski L, Baranowski P, Siedlecki JA | Int J Hematol |
| Gene expression profile and toxic effects in human bronchial epithelial cells exposed to zearalenone. | So MY, Tian Z, Phoon YS, Sha S, Antoniou MN, Zhang J, Wu RS, Tan-Un KC | PLoS One |
| Screening for herbal medicines that affect ZIC1 gene methylation in colorectal cancer | Sung-Hwa Sohn, Kwangho Cho, Hyunsu Bae | Molecular & Cellular Toxicology |
| High levels of global DNA methylation are an independent adverse prognostic factor in a series of 90 patients with de novo myelodysplastic syndrome. | Calvo X, Nomdedeu M, Navarro A, Tejero R, Costa D, Muñoz C, Pereira A, Peña O, Risueño RM, Monzó M, Esteve J, Nomdedeu B | Leuk Res |
| Epigenetic alterations induced by ambient particulate matter in mouse macrophages. | Miousse IR, Chalbot MC, Aykin-Burns N, Wang X, Basnakian A, Kavouras IG, Koturbash I | Environ Mol Mutagen |
| DNA methylation profiling in the thalamus and hippocampus of postnatal malnourished mice, including effects related to long-term potentiation. | Weng X, Zhou D, Liu F, Zhang H, Ye J, Zhang Z, Zhang D, Wang Y, Tao L, Cao L, Kan M, Wang T, Feng G, Qin X, Sun J, He L, Liu Y | BMC Neurosci |
| Maternal high folic acid supplement promotes glucose intolerance and insulin resistance in male mouse offspring fed a high-fat diet. | Huang Y, He Y, Sun X, He Y, Li Y, Sun C | Int J Mol Sci |
| Social isolation-induced epigenetic changes in midbrain of adult mice. | Siuda D, Wu Z, Chen Y, Guo L, Linke M, Zechner U, Xia N, Reifenberg G, Kleinert H, Forstermann U, Li H | J Physiol Pharmacol |
| piRNA-823 contributes to tumorigenesis by regulating de novo DNA methylation and angiogenesis in multiple myeloma. | Yan H, Wu QL, Sun CY, Ai LS, Deng J, Zhang L, Chen L, Chu ZB, Tang B, Wang K, Wu XF, Xu J, Hu Y | Leukemia |
| SDHB mutations are associated with response to temozolomide in patients with metastatic pheochromocytoma or paraganglioma. | Hadoux J, Favier J, Scoazec JY, Leboulleux S, Al Ghuzlan A, Caramella C, Déandreis D, Borget I, Loriot C, Chougnet C, Letouzé E, Young J, Amar L, Bertherat J, Libé R, Dumont F, Deschamps F, Schlumberger M, Gimenez-Roqueplo AP, Baudin E | Int J Cancer |
| Effects of epigenetic modificators in combination with small molecule inhibitors of receptor tyrosine kinases on medulloblastoma growth. | Marino AM, Frijhoff J, Calero R, Baryawno N, Ostman A, Johnsen JI | Biochem Biophys Res Commun |
| Decreased global methylation in patients with bipolar disorder who respond to lithium. | Huzayyin AA, Andreazza AC, Turecki G, Cruceanu C, Rouleau GA, Alda M, Young LT | Int J Neuropsychopharmacol |
| Do epigenetic events take place in the vastus lateralis of patients with mild chronic obstructive pulmonary disease? | Puig-Vilanova E, Ausin P, Martinez-Llorens J, Gea J, Barreiro E | PLoS One |
| Maternal vitamin D deficiency during pregnancy results in insulin resistance in rat offspring, which is associated with inflammation and Iκbα methylation. | Zhang H, Chu X, Huang Y, Li G, Wang Y, Li Y, Sun C | Diabetologia |
| Parp inhibition prevents ten eleven translocase enzyme activation and hyperglycemia induced DNA demethylation. | Dhliwayo N, Sarras MP Jr, Luczkowski E, Mason S, Intine RV | Diabetes |
| miR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia. | Ufkin ML, Peterson S, Yang X, Driscoll H, Duarte C, Sathyanarayana P | Leuk Res |
| One-pot approach for examining the DNA methylation patterns using an engineered methyl-probe. | Kim SE, Chang M, Yuan C | Biosens Bioelectron |
| Vitamin C Protects Against UV Irradiation-Induced Apoptosis Through Reactivating Silenced Tumor Suppressor Genes p21 and p16 in a Tet-Dependent DNA Demethylation Manner in Human Skin Cancer Cells. | Lin JR, Qin HH, Wu WY, He SJ, Xu JH | Cancer Biother Radiopharm |
| Colon cancer cell apoptosis is induced by combined exposure to the n-3 fatty acid docosahexaenoic acid and butyrate through promoter methylation. | Cho Y, Turner ND, Davidson LA, Chapkin RS, Carroll RJ, Lupton JR | Exp Biol Med (Maywood) |
| Inhibition of histone demethylase, LSD2 (KDM1B), attenuates DNA methylation and increases sensitivity to DNMT inhibitor-induced apoptosis in breast cancer cells. | Katz TA, Vasilatos SN, Harrington E, Oesterreich S, Davidson NE, Huang Y | Breast Cancer Res Treat |
| Genome-Wide Demethylation by 5-aza-2'-Deoxycytidine Alters the Cell Fate of Stem/Progenitor Cells. | Zhou Y, Hu Z | Stem Cell Rev |
| Impact of 5-Aza-2`-deoxycytidine and Epigallocatechin-3-gallate for induction of human regulatory T cells. | Kehrmann J, Tatura R, Zeschnigk M, Probst-Kepper M, Geffers R, Steinmann J, Buer J | Immunology |
| Global and cyp19a1a gene specific DNA methylation in gonads of adult rare minnow Gobiocypris rarus under bisphenol A exposure. | Liu Y, Yuan C, Chen S, Zheng Y, Zhang Y, Gao J, Wang Z | Aquat Toxicol |
| Morphine induces redox-based changes in global DNA methylation and retrotransposon transcription by inhibition of excitatory amino acid transporter type 3-mediated cysteine uptake. | Trivedi M, Shah J, Hodgson N, Byun HM, Deth R | Mol Pharmacol |
| Maternal separation is associated with DNA methylation and behavioural changes in adult rats. | Anier K, Malinovskaja K, Pruus K, Aonurm-Helm A, Zharkovsky A, Kalda A | Eur Neuropsychopharmacol |
| Genome-wide DNA methylation changes in skeletal muscle between young and middle-aged pigs. | Jin L, Jiang Z, Xia Y, Lou P, Chen L, Wang H, Bai L, Xie Y, Liu Y, Li W, Zhong B, Shen J, Jiang A, Zhu L, Wang J, Li X, Li M | BMC Genomics |
| The role of DNA methylation in stress-related psychiatric disorders. | Klengel T, Pape J, Binder EB, Mehta D | Neuropharmacology |
| Distinct and overlapping control of 5-methylcytosine and 5-hydroxymethylcytosine by the TET proteins in human cancer cells. | Putiri EL, Tiedemann RL, Thompson JJ, Liu C, Ho T, Choi JH, Robertson KD | Genome Biol |
| Dietary l-methionine supplementation mitigates gamma-radiation induced global DNA hypomethylation: Enhanced metabolic flux towards S-adenosyl-l-methionine (SAM) biosynthesis increases genomic methylation potential. | Batra V, Verma P | Food Chem Toxicol |
| Changes in DNA methylation levels and nuclear distribution patterns after microspore reprogramming to embryogenesis in barley. | El-Tantawy AA, SolÃs MT, Risueño MC, Testillano PS | Cytogenet Genome Res |
| Transgenerational impaired male fertility with an Igf2 epigenetic defect in the rat are induced by the endocrine disruptor, p,p'-DDE. | Song Y, Wu N, Wang S, Gao M, Song P, Lou J, Tan Y, Liu K | Hum Reprod |
| Early markers are present in both embryogenesis pathways from microspores and immature zygotic embryos in cork oak, Quercus suber L. | RodrÃguez-Sanz H, Manzanera JA, SolÃs MT, Gómez-Garay A, Pintos B, Risueño MC, Testillano PS | BMC Plant Biol |
| Global DNA modifications suppress transcription in brown adipose tissue during hibernation. | Biggar Y, Storey KB | Cryobiology |
| Frequent Silencing of RASSF1A via Promoter Methylation in Follicular Thyroid Hyperplasia: A Potential Early Epigenetic Susceptibility Event in Thyroid Carcinogenesis. | Brown TC, Juhlin CC, Healy JM, Prasad ML, Korah R, Carling T | JAMA Surg |
| Alterations in global DNA methylation and hydroxymethylation are not detected in Alzheimer's disease. | Lashley T, Gami P, Valizadeh N, Li A, Revesz T, Balazs R | Neuropathol Appl Neurobiol |
| Epigenetic regulation during hepatic stellate cell activation. | Götze S, Quenkert E, Kordes C, Sawitza I, Häussinger D | Eur J Med Res |
| Expression and epigenetic profile of protoplast cultures (Cucumis sativus L.) | Petr Cápal, Vladan Ondřej | In Vitro Cellular & Developmental Biology - Plant |
| Radiation-induced changes in DNA methylation and their relationship to chromosome aberrations in nuclear power plant workers. | Lee Y, Kim YJ, Choi YJ, Lee JW, Lee S, Cho YH, Chung HW | Int J Radiat Biol |
| The deregulated promoter methylation of the Polo-like kinases as a potential biomarker in hematological malignancies. | Ward A, Sivakumar G, Kanjeekal S, Hamm C, Labute B, Shum D, Hudson JW | Leuk Lymphoma |
| The consequence of level of nutrition on heifer ovarian and mammary development. | Freetly HC, Vonnahme KA, McNeel AK, Camacho LE, Amundson OL, Forbes ED, Lents CA, Cushman RA | J Anim Sci |
| Anxiety is associated with higher levels of global DNA methylation and altered expression of epigenetic and interleukin-6 genes. | Murphy TM, O'Donovan A, Mullins N, O'Farrelly C, McCann A, Malone K | Psychiatr Genet |
| Epigenetic mechanisms in respiratory muscle dysfunction of patients with chronic obstructive pulmonary disease. | Puig-Vilanova E, Aguiló R, RodrÃguez-Fuster A, MartÃnez-Llorens J, Gea J, Barreiro E | PLoS One |
| DNA Methyltransferase 1 Drives Transcriptional Down-Modulation of β Catenin Antagonist Chibby1 Associated With the BCR-ABL1 Gene of Chronic Myeloid Leukemia. | Leo E, Mancini M, Castagnetti F, Gugliotta G, Santucci MA, Martinelli G | J Cell Biochem |
| IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions. | Naito T, Nosho K, Ito M, Igarashi H, Mitsuhashi K, Yoshii S, Aoki H, Nomura M, Sukawa Y, Yamamoto E, Adachi Y, Takahashi H, Hosokawa M, Fujita M, Takenouchi T, Maruyama R, Suzuki H, Baba Y, Imai K, Yamamoto H, Ogino S, Shinomura Y | World J Gastroenterol |
| DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2. | Lopez-Bertoni H, Lal B, Li A, Caplan M, Guerrero-Cázares H, Eberhart CG, Quiñones-Hinojosa A, Glas M, Scheffler B, Laterra J, Li Y | Oncogene |
| Oligonucleotide treatment causes flax ß-glucanase up-regulation via changes in gene-body methylation. | Wojtasik W, Kulma A, Boba A, Szopa J | BMC Plant Biol |
| Dynamic changes in the cardiac methylome during postnatal development. | Sim CB, Ziemann M, Kaspi A, Harikrishnan KN, Ooi J, Khurana I, Chang L, Hudson JE, El-Osta A, Porrello ER | FASEB J |
| Epigenetic Features Induced by Ischemia-Hypoxia in Cultured Rat Astrocytes. | Yang Q, Wu X, Sun J, Cui J, Li L | Mol Neurobiol |
| CB1-Receptor Knockout Neonatal Mice are Protected Against Ethanol-induced Impairments of DNMT1, DNMT3A and DNA Methylation. | Nagre NN, Subbanna S, Shivakumar M, Psychoyos D, Basavarajappa BS | J Neurochem |
| The relative importance of DNA methylation and Dnmt2-mediated epigenetic regulation on Wolbachia densities and cytoplasmic incompatibility. | LePage DP, Jernigan KK, Bordenstein SR | PeerJ |
| Epigenetic modulation of the muscarinic type 3 receptor in salivary epithelial cells. | Shin YH, Jin M, Hwang SM, Choi SK, Namkoong E, Kim M, Park MY, Choi SY, Lee JH, Park K | Lab Invest |
| p38 MAPK down-regulates fibulin 3 expression through methylation of gene regulatory sequences. Role in migration and invasion. | Arechederra M, Priego N, Vazquez-Carballo A, Sequera C, Gutierrez-Uzquiza A, Cerezo-Guisado MI, Ortiz-Rivero S, Roncero C, Cuenda A, Guerrero C, Porras A | J Biol Chem |
| Caffeine exposure alters cardiac gene expression in embryonic cardiomyocytes. | Fang X, Mei W, Barbazuk WB, Rivkees SA, Wendler CC | Am J Physiol Regul Integr Comp Physiol |
| Specific but interdependent functions for Arabidopsis AGO4 and AGO6 in RNA-directed DNA methylation. | Duan CG, Zhang H, Tang K, Zhu X, Qian W, Hou YJ, Wang B, Lang Z, Zhao Y, Wang X, Wang P, Zhou J, Liang G, Liu N, Wang C, Zhu JK | EMBO J |
| Aberrant hypermethylation of aldehyde dehydrogenase 2 promoter upstream sequence in rats with experimental myocardial infarction. | Wang P, Shen C, Diao L, Yang Z, Fan F, Wang C, Liu X, Sun X, Dong Z, Zhu H, Ma X, Cao Q, Zhao X, Ma D, Zou Y, Hu K, Sun A, Ge J | Biomed Res Int |
| The effect of mycophenolic acid on epigenetic modifications in lupus CD4<sup>+</sup>T cells. | Yang Y, Tang Q, Zhao M, Liang G, Wu H, Li D, Xie Y, Tan Y, Dai Y, Yung S, Chan TM, Lu Q | Clin Immunol |
| DNA Methyl Transferase 1 Reduces Expression of SRD5A2 in the Aging Adult Prostate. | Ge R, Wang Z, Bechis SK, Otsetov AG, Hua S, Wu S, Wu CL, Tabatabaei S, Olumi AF | Am J Pathol |
| Androgen receptor and histone lysine demethylases in ovine placenta. | Cleys ER, Halleran JL, Enriquez VA, da Silveira JC, West RC, Winger QA, Anthony RV, Bruemmer JE, Clay CM, Bouma GJ | PLoS One |
| Evaluating the effect of ambient particulate pollution on DNA methylation in Alaskan sled dogs: Potential applications for a sentinel model of human health. | Montrose L, Noonan CW, Cho YH, Lee J, Harley J, O'Hara T, Cahill C, Ward TJ | Sci Total Environ |
| Male obesity is associated with changed spermatozoa Cox4i1 mRNA level and altered seminal vesicle fluid composition in a mouse model. | Binder NK, Sheedy JR, Hannan NJ, Gardner DK | Mol Hum Reprod |
| Paternal obesity in a rodent model affects placental gene expression in a sex-specific manner. | Binder NK, Beard SA, Kaitu'u-Lino TJ, Tong S, Hannan NJ, Gardner D | Reproduction |
| Characterization of a potato activation-tagged mutant, nikku, and its partial revertant. | Aulakh SS, Veilleux RE, Tang G, Flinn BS | Planta |
| Decitabine Nanoconjugate Sensitizes Human Glioblastoma Cells to Temozolomide. | Cui Y, Naz A, Thompson DH, Irudayaraj J | Mol Pharm |
| Cortisol Is Not Associated with Telomere Shortening or Chromosomal Instability in Human Lymphocytes Cultured under Low and High Folate Conditions. | Bull C, Christensen H, Fenech M | PLoS One |
| Dissecting the behavior and function of MBD3 in DNA methylation homeostasis by single-molecule spectroscopy and microscopy. | Cui Y, Irudayaraj J | Nucleic Acids Res |
| Capsaicin-induced genotoxic stress does not promote apoptosis in A549 human lung and DU145 prostate cancer cells. | Lewinskaa A, Jaroszb P, Czechb J, Rzeszutekb I, Bielak-Zmijewskac A, Grabowskac W, Wnukb M | Mutation Res |
| Parental Neuropathic Pain Influences Emotion-Related Behavior in Offspring Through Maternal Feeding Associated with DNA Methylation of Amygdale in Rats. | Zhong T, Zhang Y, Guo Q, Yang Y, Yan J, Dai R, Wu H | Neurochem Res |
| Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline. | Mei Y, Jiang C, Wan Y, Lv J, Jia J, Wang X, Yang X, Tong Z | Aging Cell |
| DNA Methylation and Transcriptomic Changes in Response to Different Lights and Stresses in 7B-1 Male-Sterile Tomato. | Omidvar V, Fellner M | PLoS One |
| Elevated tissue Cr levels, increased plasma oxidative markers, and global hypomethylation of blood DNA in male Sprague-Dawley rats exposed to potassium dichromate in drinking water. | Wang Y, Wu W, Yao C, Lou J, Chen R, Jin L, Wu N, Gao M, Song P, Tan Y, Liu K | Environ Toxicol |
| Analysis of DNA Methylation and Gene Expression in Radiation-Resistant Head and Neck Tumors. | Chen X, Liu L, Mims J, Punska EC, Williams KE, Zhao W, Arcaro KF, Tsang AW, Zhou X, Furdui CM | Epigenetics |
| Postmitotic regulation of sensory area patterning in the mammalian neocortex by Lhx2. | Zembrzycki A, Perez-Garcia CG, Wang CF, Chou SJ, O'Leary DD | Proc Natl Acad Sci U S A |
| Piwil1 causes epigenetic alteration of PTEN gene via upregulation of DNA methyltransferase in type I endometrial cancer. | Chen Z, Che Q, Jiang FZ, Wang HH, Wang FY, Liao Y, Wan XP | Biochem Biophys Res Commun |
| Epigenetic Changes during Hepatic Stellate Cell Activation. | Götze S, Schumacher EC, Kordes C, Häussinger D | PLoS One |
| Tet3 mediates stable glucocorticoid-induced alterations in DNA methylation and Dnmt3a/Dkk1 expression in neural progenitors. | Bose R, Spulber S, Kilian P, Heldring N, Lönnerberg P, Johnsson A, Conti M, Hermanson O, Ceccatelli S | Cell Death Dis |
| D2HGDH regulates alpha-ketoglutarate levels and dioxygenase function by modulating IDH2. | Lin AP, Abbas S, Kim SW, Ortega M, Bouamar H, Escobedo Y, Varadarajan P, Qin Y, Sudderth J, Schulz E, Deutsch A, Mohan S, Ulz P, Neumeister P, Rakheja D, Gao X, Hinck A, Weintraub ST, DeBerardinis RJ, Sill H, Dahia PL, Aguiar RC | Nat Commun |
| Investigating the effects of in utero benzene exposure on epigenetic modifications in maternal and fetal CD-1 mice. | Philbrook NA, Winn LM | Toxicol Appl Pharmacol |
| Cyclic AMP induces hypertrophy and alters DNA methylation in HL-1 cardiomyocytes. | Fang X, Robinson J, Wang-Hu J, Jiang L, Freeman DA, Rivkees SA, Wendler CC | Am J Physiol Cell Physiol |
| Developmental profiles and expression of the DNA methyltransferase genes in the fathead minnow (Pimephales promelas) following exposure to di-2-ethylhexyl phthalate. | Wood RK, Crowley E, Martyniuk CJ | Fish Physiol Biochem |
| Alterations in DNA methylation corresponding with lung inflammation and as a biomarker for disease development after MWCNT exposure. | Brown TA, Lee JW, Holian A, Porter V, Fredriksen H, Kim M, Cho YH | Nanotoxicology |
| Contributions of the Epidermal Growth Factor Receptor to Acquisition of Platinum Resistance in Ovarian Cancer Cells. | Granados ML, Hudson LG, Samudio-Ruiz SL | PLoS One |
| Epigenetic alteration of the purinergic type 7 receptor in salivary epithelial cells. | Shin YH, Kim M, Kim N, Choi SK, Namkoong E, Choi SY, Lee JH, Cha S, Park K | Biochem Biophys Res Commun |
| Epigenetic modulations in early endothelial cells and DNA hypermethylation in human skin after sulfur mustard exposure. | Steinritz D, Schmidt A, Balszuweit F, Thiermann H, Simons T, Striepling E, Bölck B, Bloch W | Toxicol Lett |
| 5-azacytidine promotes microspore embryogenesis initiation by decreasing global DNA methylation, but prevents subsequent embryo development in rapeseed and barley. | SolÃs MT, El-Tantawy AA, Cano V, Risueño MC, Testillano PS | Front Plant Sci |
| Global DNA methylation and homocysteine ​​levels are lower in type 1 diabetes patients | Arroyo-Jousse V, Diego F. Garcia-Diaz, Francisco Pérez-Bravo | Rev. méd. Chile |
| Effect of combined deferasirox and 5-azacytidine treatment on human leukemia cells in vitro. | Imanishi S, Takahashi R, Ohsuga M, Ohyashiki K, Ohyashiki JH | Ann Hematol |
| CGGBP1 mitigates cytosine methylation at repetitive DNA sequences. | Agarwal P, Collier P, Fritz MH, Benes V, Wiklund HJ, Westermark B, Singh U | BMC Genomics |
| Mitochondrial DNA variants can mediate methylation status of inflammation, angiogenesis and signaling genes. | Atilano SR, Malik D, Chwa M, Cáceres-Del-Carpio J, Nesburn AB, Boyer DS, Kuppermann BD, Jazwinski SM, Miceli MV, Wallace DC, Udar N, Kenney MC | Hum Mol Genet |
| Seed response to strigolactone is controlled by abscisic acid-independent DNA methylation in the obligate root parasitic plant, Phelipanche ramosa L. Pomel. | Lechat MM, Brun G, Montiel G, Véronési C, Simier P, Thoiron S, Pouvreau JB, Delavault P | J Exp Bot |
| DNA methylation and histone modification patterns during the late embryonic and early postnatal development of chickens. | Li C, Guo S, Zhang M, Gao J, Guo Y | Poult Sci |
| MiR125a-5p acting as a novel Gab2 suppressor inhibits invasion of glioma. | Sun L, Zhang B, Liu Y, Shi L, Li H, Lu S | Mol Carcinog |
| Liver DNA methylation analysis in adult female C57BL/6JxFVB mice following perinatal exposure to bisphenol A. | van Esterik JC, Vitins AP, Hodemaekers HM, Kamstra JH, Legler J, Pennings JL, Steegenga WT, Lute C, Jelinek J, Issa JP, Dollé ME, van der Ven LT | Toxicol Lett |
| P651 Identification of new genetic variants related to thiopurine-induced myelotoxicity in inflammatory bowel disease (IBD) patients with normal thiopurines-methyltransferase (TPMT): a genome-wide association study | Chaparro, M, A. González-Neira, M. Román, G. Pita, T. Cabaleiro, D. Herrero, B. Herráez, R. Alonso, C. Taxonera, P. López-Serran | J Crohns Colitis |
| Selective increase in subtelomeric DNA methylation: an epigenetic biomarker for malignant glioma. | Choudhury SR, Cui Y, Milton JR, Li J, Irudayaraj J | Clin Epigenetics |
| Effect of the one‑carbon unit cycle on overall DNA methylation in children with Down's syndrome. | Song C, He J, Chen J, Liu Y, Xiong F, Wang Y, Li T | Mol Med Rep |
| Establishment of Acute myeloid leukemic xenografts as preclinical models of epigenetic therapies | Patel S, Yanyan Zhang, Audrey Cras, Mallorie Mangean, Fabien Zassadowski, Victor Maud, Bruno Cassinat, Christine Chomie | Int J Hematol Res. |
| The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models. | Hervouet E, Claude-Taupin A, Gauthier T, Perez V, Fraichard A, Adami P, Despouy G, Monnien F, Algros MP, Jouvenot M, Delage-Mourroux R, Boyer-Guittaut M | BMC Cancer |
| The Relationship Between Cognitive Impairment and Global DNA Methylation Decrease Among Aluminum Potroom Workers. | Yang X, Yuan Y, Lu X, Yang J, Wang L, Song J, Nie J, Zhang Q, Niu Q | J Occup Environ Med |
| DNA Methylation Modulates Nociceptive Sensitization after Incision. | Sun Y, Sahbaie P, Liang D, Li W, Shi X, Kingery P, Clark JD | PLoS One |
| Preclinical studies of 5-fluoro-2'-deoxycytidine and tetrahydrouridine in pediatric brain tumors. | Morfouace M, Nimmervoll B, Boulos N, Patel YT, Shelat A, Freeman BB 3rd, Robinson GW, Wright K, Gajjar A, Stewart CF, Gilbertson RJ, Roussel MF | J Neurooncol |
| Immunomodulatory drugs act as inhibitors of DNA methyltransferases and induce PU.1 up-regulation in myeloma cells | Endo S, Masayuki Amano, Nao Nishimura, Niina Ueno, Shikiko Ueno, Hiromichi Yuki, Shiho Fujiwara, Naoko Wada, Shinya Hirata, | Biochem Biophys Res Commun |
| Effect of Obesity on the Preovulatory Follicle and Lipid Fingerprint of Equine Oocytes. | Sessions-Bresnahan DR, Schauer KL, Heuberger AL, Carnevale EM | Biol Reprod |
| Epigenetic modulation of Chlorella (Chlorella vulgaris) on exposure to polycyclic aromatic hydrocarbons. | Yang M, Youn JI, Kim SJ, Park JY | Environ Toxicol Pharmacol |
| Dnmts and Tet target memory-associated genes after appetitive olfactory training in honey bees. | Biergans SD, Giovanni Galizia C, Reinhard J, Claudianos C | Sci Rep |
| Dnmt3a in the Medial Prefrontal Cortex Regulates Anxiety-Like Behavior in Adult Mice. | Elliott E, Manashirov S, Zwang R, Gil S, Tsoory M, Shemesh Y, Chen A | J Neurosci |
| Genomic DNA hypomethylation and risk of renal cell carcinoma: A case-control study. | Mendoza-Perez J, Gu J, Herrera LA, Tannir NM, Matin SF, Karam JA, Huang M, Chang DW, Wood CG, Wu X | Clin Cancer Res |
| Translocation of bacteria from the gut to the eggs triggers maternal transgenerational immune priming in Tribolium castaneum. | Knorr E, Schmidtberg H, Arslan D, Bingsohn L, Vilcinskas A | Biol Lett |
| Cryptophyte gene regulation in the kleptoplastidic, karyokleptic ciliate Mesodinium rubrum | Kima GH, Ji Hee Hana, Bora Kima, Jong Won Hanb, Seung Won Namc, Woongghi Shinc, Jong Woo Parkd, Wonho Yihe | Harmful Algae |
| A correlation study on the effects of DNMT1 on methylation levels in CD4+ T cells of SLE patients. | Liang J, Xiao-Hua Zhu, Hai-Hong Qin, Jin-Ran Lin, Duo-Qin Wang, Lan Huang, Xiao-Qun Luo, Jin-Hua Xu | Int J Clin Exp Med |
| Association between early promoter-specific DNA methylation changes and outcome in older acute myeloid leukemia patients. | Achille NJ, Othus M, Phelan K, Zhang S, Cooper K, Godwin JE, Appelbaum FR, Radich JP, Erba HP, Nand S, Zeleznik-Le NJ | Leuk Res |
| DNA Methylation Analysis: Choosing the Right Method. | Kurdyukov S, Bullock M | Biology (Basel) |
| The role of DNA methylation during anoxia tolerance in a freshwater turtle (Trachemys scripta elegans). | Wijenayake S, Storey KB | J Comp Physiol B |
| Epigenetic toxicity of trichloroethylene: a single-molecule perspective | Cui Y, Choudhury S, Irudayaraj J | Toxicol Res |
| Effects of Wutou Decoction on DNA Methylation and Histone Modifications in Rats with Collagen-Induced Arthritis | Liu Y, Wen C, Chen Z, Wang Y, Huang Y, Hu Y, Tu S | Evid. Based Complement. Alternat. Med. |
| The green tea polyphenol EGCG alleviates maternal diabetes-induced neural tube defects by inhibiting DNA hypermethylation. | Zhong J, Xu C, Reece EA, Yang P | Am J Obstet Gynecol |
| Sperm global DNA methylation level: association with semen parameters and genome integrity. | Montjean D, Zini A, Ravel C, Belloc S, Dalleac A, Copin H, Boyer P, McElreavey K, Benkhalifa M | Andrology |
| Maternal high-zinc diet attenuates intestinal inflammation by reducing DNA methylation and elevating H3K9 acetylation in the A20 promoter of offspring chicks. | Li C, Guo S, Gao J, Guo Y, Du E, Lv Z, Zhang B | J Nutr Biochem |
| Molecular mechanisms of repeated social defeat-induced glucocorticoid resistance: Role of microRNA. | Jung SH, Wang Y, Kim T, Tarr A, Reader B, Powell N, Sheridan JF | Brain Behav Immun |
| Maternal vitamin B<sub>6</sub> deficient or supplemented diets on expression of genes related to GABAergic, serotonergic or glutamatergic pathways in hippocampus of rat dams and their offspring. | Almeida MR, Mabasa L, Crane C, Park CS, Venâncio VP, Bianchi ML, Antunes LM | Mol Nutr Food Res |
| Deposition of 5-Methylcytosine on Enhancer RNAs Enables the Coactivator Function of PGC-1α. | Aguilo F, Li S, Balasubramaniyan N, Sancho A, Benko S, Zhang F, Vashisht A, Rengasamy M, Andino B, Chen CH, Zhou F, Qian C, Zhou MM, Wohlschlegel JA, Zhang W, Suchy FJ, Walsh MJ | Cell Rep |
| A Novel Combinatorial Epigenetic Therapy Using Resveratrol and Pterostilbene for Restoring Estrogen Receptor-α (ERα) Expression in ERα-Negative Breast Cancer Cells. | Kala R, Tollefsbol TO | PLoS One |
| Reprogrammable CRISPR/Cas9-based system for inducing site-specific DNA methylation. | McDonald JI, Celik H, Rois LE, Fishberger G, Fowler T, Rees R, Kramer A, Martens A, Edwards JR, Challen GA | Biol Open |
| Long-Term Epigenetic Alterations in a Rat Model of Gulf War Illness. | Pierce LM, Kurata WE, Matsumoto KW, Clark ME, Farmer DM | Neurotoxicology |
| Associations between whole peripheral blood fatty acids and DNA methylation in humans. | de la Rocha C, Pérez-Mojica JE, León SZ, Cervantes-Paz B, Tristán-Flores FE, RodrÃguez-RÃos D, Molina-Torres J, RamÃrez-Chávez E, Alvarado-Caudillo Y, Carmona FJ, Esteller M, Hernández-Rivas R, Wrobel K, Wrobel K, Zaina S, Lund G | Sci Rep |
| Abnormal Epigenetic Modifications in Peripheral T Cells from Patients with Abdominal Aortic Aneurysm Are Correlated with Disease Development. | Jiang H, Xia Q, Xin S, Lun Y, Song J, Tang D, Liu X, Ren J, Duan Z, Zhang J | J Vasc Res |
| Procaine Inhibits Osteo/Odontogenesis through Wnt/β-Catenin Inactivation. | Herencia C, Diaz-Tocados JM, Jurado L, Montes de Oca A, RodrÃguez-Ortiz ME, MartÃn-Alonso C, MartÃnez-Moreno JM, Vergara N, RodrÃguez M, Almadén Y, Muñoz-Castañeda JR | PLoS One |
| Expression of TET2 enzyme indicates enhanced epigenetic modification of cells in periodontitis. | Larsson L, Thorbert-Mros S, Lopez-Lago A, Kalm J, Shikhan A, Berglundh T | Eur J Oral Sci |
| Knockdown of DNA methyltransferase 3a alters gene expression and inhibits function of embryonic cardiomyocytes. | Fang X, Poulsen RR, Wang-Hu J, Shi O, Calvo NS, Simmons CS, Rivkees SA, Wendler CC | FASEB J |
| The Epigenomic Marker Global DNA Methylation is Related to Measures of Body Composition and Aerobic Capacity in Females but not in Males | Navalta J, Jarrett M, Ciulei M, Young J | Research Gate |
| Egg-specific expression of protein with DNA methyltransferase activity in the biocarcinogenic liver fluke Clonorchis sinensis. | Kim SH, Cho HJ, Sohn WM, Ahn CS, Kong Y, Yang HJ, Bae YA | Parasitology |
| Variation of DNA Methylome of Zebrafish Cells under Cold Pressure. | Han B, Li W, Chen Z, Xu Q, Luo J, Shi Y, Li X, Yan X, Zhang J | PLoS One |
| Ocean acidification influences host DNA methylation and phenotypic plasticity in environmentally susceptible corals | Putnam HM, Jennifer M Davidson and Ruth D Gates | Evol Appl |
| The sensitivity of 5-formylcytosine to doxorubicin regardless of DNA damage | ZUNER, SELCEN ÇELİK and O'NEILL, CHRIS | Turk J Biol |
| Maternal Calorie Restriction Causing Utero-placental Insufficiency Differentially Affects Mammalian Placental Glucose and Leucine Transport Molecular Mechanisms. | Ganguly A, Touma M, Thamotharan S, De Vivo DC, Devaskar SU | Endocrinology |
| Methylation pattern analysis in prostate cancer tissue: identification of biomarkers using an MS-MLPA approach. | Gurioli G, Salvi S, Martignano F, Foca F, Gunelli R, Costantini M, Cicchetti G, De Giorgi U, Sbarba PD, Calistri D, Casadio V | J Transl Med |
| A single day of 5-azacytidine exposure during development induces neurodegeneration in neonatal mice and neurobehavioral deficits in adult mice. | Subbanna S, Nagre NN, Shivakumar M, Basavarajappa BS | Physiol Behav |
| Cell-Wide DNA De-Methylation and Re-Methylation of Purkinje Neurons in the Developing Cerebellum. | Zhou FC, Resendiz M, Lo CL, Chen Y | PLoS One |
| Remodelling of the hepatic epigenetic landscape of glucose-intolerant rainbow trout (Oncorhynchus mykiss) by nutritional status and dietary carbohydrates. | Marandel L, Lepais O, Arbenoits E, Véron V, Dias K, Zion M, Panserat S | Sci Rep |
| Increased global placental DNA methylation levels are associated with gestational diabetes. | Reichetzeder C, Dwi Putra SE, Pfab T, Slowinski T, Neuber C, Kleuser B, Hocher B | Clin Epigenetics |
| Redox/methylation mediated abnormal DNA methylation as regulators of ambient fine particulate matter-induced neurodevelopment related impairment in human neuronal cells. | Wei H, Liang F, Meng G, Nie Z, Zhou R, Cheng W, Wu X, Feng Y, Wang Y | Sci Rep |
| Physiological and biochemical aspects of methionine isomers and a methionine analogue in broilers. | Zhang S, Saremi B, Gilbert ER, Wong EA | Poult Sci |
| Examination of Global Methylation and Targeted Imprinted Genes in Prader- Willi Syndrome | Ann Manzardo, Merlin Butler | Imedpub |
| Environmental Enrichment Modified Epigenetic Mechanisms in SAMP8 Mouse Hippocampus by Reducing Oxidative Stress and Inflammaging and Achieving Neuroprotection | Christian Griñan-Ferré, Dolors Puigoriol-Illamola, Verónica Palomera-Ãvalos, David Pérez-Cáceres, Júlia Companys-Alemany et. al. | Frontiers in Aging Neuroscience |
| Epigenetic regulation of CFTR in salivary gland. | Shin YH, Lee SW, Kim M, Choi SY, Cong X, Yu GY, Park K | Biochem Biophys Res Commun |
| DNA methyltransferases and stress-related genes expression in zebrafish larvae after exposure to heat and copper during reprogramming of DNA methylation. | Dorts J, Falisse E, Schoofs E, Flamion E, Kestemont P, Silvestre F | Sci Rep |
| Sex-Specific Effects of Testosterone on the Sexually Dimorphic Transcriptome and Epigenome of Embryonic Neural Stem/Progenitor Cells. | Bramble MS, Roach L, Lipson A, Vashist N, Eskin A, Ngun T, Gosschalk JE, Klein S, Barseghyan H, Arboleda VA, Vilain E | Sci Rep |
| Muscle catabolic capacities and global hepatic epigenome are modified in juvenile rainbow trout fed different vitamin levels at first feeding | Stéphane Panserata, Lucie Marandela, Inge Geurdena, Vincent Verona, Karine Diasa, Elisabeth Plagnes-Juana, Et Al. | Aquaculture |
| Circadian alterations during early stages of Alzheimer's disease are associated with aberrant cycles of DNA methylation in BMAL1. | Cronin P, McCarthy MJ, Lim AS, Salmon DP, Galasko D, Masliah E, De Jager PL, Bennett DA, Desplats P | Alzheimers Dement |
| Diosmin-induced senescence, apoptosis and autophagy in breast cancer cells of different p53 status and ERK activity. | Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Deregowska A, Wnuk M | Toxicol Lett |
| Methylation specific targeting of a chromatin remodeling complex from sponges to humans. | Cramer JM, Pohlmann D, Gomez F, Mark L, Kornegay B, Hall C, Siraliev-Perez E, Walavalkar NM, Sperlazza MJ, Bilinovich S, Prokop JW, Hill AL, Williams DC Jr | Sci Rep |
| Downregulation of Methyltransferase Dnmt2 Results in Condition-dependent Telomere Shortening and Senescence or Apoptosis in Mouse Fibroblasts. | Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Wnuk M | J Cell Physiol |
| Genetic variants, PM<sub>2.5</sub> exposure level and global DNA methylation level: A multi-center population-based study in Chinese. | Liu J, Xie K, Chen W, Zhu M, Shen W, Yuan J, Cheng Y, Geng L, Wang Y, Li Z, Zhang J, Jin G, Dai J, Ma H, Du J, Wang M, Zhang Z | Toxicol Lett |
| DNA Methylation program in normal and alcohol-induced thinning cortex | Nail Can Öztürk, Marisol Resendiz, Hakan Öztürk, Feng C. Zhou | Alcohol |
| Association between lifestyle factors and global DNA methylation among nurses and midwives working rotating nights | Pepłońska B, Jabłońska E, Bukowska A | Occup Environ Med |
| LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer. | Jiang AC, Buckingham L, Barbanera W, Korang AY, Bishesari F, Melson J | Clin Epigenetics |
| Measuring Global DNA Methylation to Assess Neurotoxicity of Titanium Dioxide Nanoparticles | Song, Bin; Zhou, Ting; Liu, Jia; Shao, LongQuan | Science of Advanced Materials |
| Differential expression of ten-eleven translocation genes in endometrial cancers. | Ciesielski P, Jóźwiak P, Wójcik-Krowiranda K, Forma E, Cwonda Å, Szczepaniec S, BieÅ„kiewicz A, BryÅ› M, KrzeÅ›lak A | Tumour Biol |
| Inflammation, Global DNA Methylation and Telomeres in Healthy Adolescents | Yutong Dong, Ying Huang, Bernard Gutin, Yanbin Dong and Haidong Zhu | The FASEB Journal |
| H. pylori modifies methylation of global genomic DNA and the gastrin gene promoter in gastric mucosal cells and gastric cancer cells | Yuan Xiea, Jian Jiang Zhou, Yan Zhao, Ting Zhang, Liu Zheng Mei | Microbial Pathogenesis |
| [Effect of peripheral bloodgenomic DNA methylation on the relationship between methyl donor status and risk of breast cancer]. | Luo WP, Du YF, Huang J, Huang WQ, Xu M, Yan B, Mo XF, Zhang CX | Zhonghua Liu Xing Bing Xue Za Zhi |
| DNA Methylation and Hydroxymethylation Profile of CD34<sup>+</sup>-Enriched Cell Products Intended for Autologous CD34<sup>+</sup> Cell Transplantation. | Rozman JZ, Pohar Perme M, Jez M, Malicev E, Krasna M, Vrtovec B, Rozman P | DNA Cell Biol |
| Serine Alleviates Oxidative Stress via Supporting Glutathione Synthesis and Methionine Cycle in Mice. | Zhou X, He L, Wu C, Zhang Y, Wu X, Yin Y | Mol Nutr Food Res |
| Differences in DNA methylation, DNA structure and embryogenesis-related gene expression between embryogenic and non embryogenic lines of Pinus radiata D. don | Bravo, S., BertÃn, A., Turner, A. et al. | PCTOC |
| Assessing multigenerational effects of prednisolone to the freshwater snail, Physa acuta (Gastropoda: Physidae). | Bal N, Kumar A, Nugegoda D | J Hazard Mater |
| MicroRNA-330-3p promotes cell invasion and metastasis in non-small cell lung cancer through GRIA3 by activating MAPK/ERK signaling pathway. | Wei CH, Wu G, Cai Q, Gao XC, Tong F, Zhou R, Zhang RG, Dong JH, Hu Y, Dong XR | J Hematol Oncol |
| Vitamin E deficiency during embryogenesis in zebrafish causes lasting metabolic and cognitive impairments despite refeeding adequate diets. | McDougall M, Choi J, Truong L, Tanguay R, Traber MG | Free Radic Biol Med |
| Epigenetic modification differences between fetal fibroblast cells and mesenchymal stem cells of the Arbas Cashmere goat. | Wang X, Wang Z, Wang Q, Wang H, Liang H, Liu D | Res Vet Sci |
| Short-term sleep deprivation leads to decreased systemic redox metabolites and altered epigenetic status. | Trivedi MS, Holger D, Bui AT, Craddock TJA, Tartar JL | PLoS One |
| DNA damage and methylation induced by glyphosate in human peripheral blood mononuclear cells (in vitro study). | Kwiatkowska M, Reszka E, Woźniak K, Jabłońska E, Michałowicz J, Bukowska B | Food Chem Toxicol |
| Significant association of cyp19a promoter methylation with environmental factors and gonadal differentiation in olive flounder Paralichthys olivaceus. | Fan Z, Zou Y, Jiao S, Tan X, Wu Z, Liang D, Zhang P, You F | Comp Biochem Physiol A Mol Integr Physiol |
| Salt-Induced Tissue-Specific Cytosine Methylation Downregulates Expression of HKT Genes in Contrasting Wheat (Triticum aestivum L.) Genotypes. | Kumar S, Beena AS, Awana M, Singh A | DNA Cell Biol |
| MicroRNA-34a Encapsulated in Hyaluronic Acid Nanoparticles Induces Epigenetic Changes with Altered Mitochondrial Bioenergetics and Apoptosis in Non-Small-Cell Lung Cancer Cells. | Trivedi M, Singh A, Talekar M, Pawar G, Shah P, Amiji M | Sci Rep |
| Intracellular adenosine regulates epigenetic programming in endothelial cells to promote angiogenesis. | Xu Y, Wang Y, Yan S, Zhou Y, Yang Q, Pan Y, Zeng X, An X, Liu Z, Wang L, Xu J, Cao Y, Fulton DJ, Weintraub NL, Bagi Z, Hoda MN, Wang X, Li Q, Hong M, Jiang X, Boison D, Weber C, Wu C, Huo Y | EMBO Mol Med |
| MeDIP-seq reveals the features of mitochondrial genomic methylation in immature testis of Chinese mitten crab Eriocheir sinensis. | Li GL, Xu YJ, Huang XM, Xiao J, Nong S, Li CG | Mitochondrial DNA A DNA Mapp Seq Anal |
| Zebrafish as an In Vivo Model to Assess Epigenetic Effects of Ionizing Radiation. | Kong EY, Cheng SH, Yu KN | Int J Mol Sci |
| Hepatic Lipid Accumulation and Nrf2 Expression following Perinatal and Peripubertal Exposure to Bisphenol A in a Mouse Model of Nonalcoholic Liver Disease | Shimpi P, More V, Paranjpe M, Donepudi A, Goodrich J, Dolinoy D, Beverly Rubin B, Slitt A. | Environmental Health Perspective |
| Gene Expression, DNA Methylation and Prognostic Significance of DNA Repair Genes in Human Bladder Cancer. | Wojtczyk-Miaskowska A, Presler M, Michajlowski J, Matuszewski M, Schlichtholz B | Cell Physiol Biochem |
| Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression. | Lewinska A, Adamczyk-Grochala J, Kwasniewicz E, Deregowska A, Semik E, Zabek T, Wnuk M | Redox Biol |
| Folate dietary insufficiency and folic acid supplementation similarly impair metabolism and compromise hematopoiesis. | Henry CJ, Nemkov T, Casas-Selves M, Bilousova G, Zaberezhnyy V, Higa KC, Serkova NJ, Hansen KC, D' Alessandro A, DeGregori J | Haematologica |
| Chronic exposure to rapamycin and episodic serum starvation modulate ageing of human fibroblasts in vitro. | Sodagam L, Lewinska A, Wnuk M, Rattan SIS | Biogerontology |
| High-level dietary cadmium exposure is associated with global DNA hypermethylation in the gastropod hepatopancreas. | Nica DV, Popescu C, Draghici GA, Andrica FM, Privistirescu IA, Gergen II, Stöger R | PLoS One |
| Sulforaphane-Induced Cell Cycle Arrest and Senescence are accompanied by DNA Hypomethylation and Changes in microRNA Profile in Breast Cancer Cells. | Lewinska A, Adamczyk-Grochala J, Deregowska A, Wnuk M | Theranostics |
| Do mutations in DNMT3A/3B affect global DNA hypomethylation among benzene-exposed workers in Southeast China?: Effects of mutations in DNMT3A/3B on global DNA hypomethylation. | Zhang GH, Lu Y, Ji BQ, Ren JC, Sun P, Ding S, Liao X, Liao K, Liu J, Cao J, Lan Q, Rothman N, Xia ZL | Environ Mol Mutagen |
| Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis. | Maiuri AR, Peng M, Sriramkumar S, Kamplain CM, DeStefano Shields CE, Sears CL, O'Hagan HM | Cancer Res |
| Haloperidol induces pharmacoepigenetic response by modulating miRNA expression, global DNA methylation and expression profiles of methylation maintenance genes and genes involved in neurotransmission in neuronal cells. | Swathy B, Banerjee M | PLoS One |
| Comparison of Blueberry (<i>Vaccinium</i> spp.) and Vitamin C via Antioxidative and Epigenetic Effects in Human. | Kim M, Na H, Kasai H, Kawai K, Li YS, Yang M | J Cancer Prev |
| Mutations in TET2 and DNMT3A genes are associated with changes in global and gene-specific methylation in acute myeloid leukemia. | Ponciano-Gómez A, MartÃnez-Tovar A, Vela-Ojeda J, Olarte-Carrillo I, Centeno-Cruz F, Garrido E | Tumour Biol |
| Metformin regulates global DNA methylation via mitochondrial one-carbon metabolism. | Cuyà s E, Fernández-Arroyo S, Verdura S, GarcÃa RÃ, Stursa J, Werner L, Blanco-González E, Montes-Bayón M, Joven J, Viollet B, Neuzil J, Menendez JA | Oncogene |
| Nuclear fragments of the neural cell adhesion molecule NCAM with or without polysialic acid differentially regulate gene expression. | Westphal N, Theis T, Loers G, Schachner M, Kleene R | Sci Rep |
| Hepatic accumulation of S-Adenosylmethionine in hamsters with non-alcoholic-fatty liver disease associated to metabolic syndrome under selenium and vitamin E deficiency. | Del Bas JM, RodrÃguez B, Puiggròs F, Mariné S, RodrÃguez MA, Moriña D, Armengol L, Caimari A, Arola L | Clin Sci (Lond) |
| Maternal Micronutrients, Omega-3 Fatty Acids and Gene Expression of Angiogenic and Inflammatory Markers in Pregnancy Induced Hypertension Rats. | Kemse N, Sundrani D, Kale A, Joshi S | Arch Med Res |
| Serine prevented high-fat diet-induced oxidative stress by activating AMPK and epigenetically modulating the expression of glutathione synthesis-related genes. | Zhou X, He L, Zuo S, Zhang Y, Wan D, Long C, Huang P, Wu X, Wu C, Liu G, Yin Y | Biochim Biophys Acta |
| Bilyaminu Abubakar, Norsharina Ismail, Abdul Rahman Omar, Md Zuki Abu bakar, Maznah Ismail | Bilyaminu Abubakar, Norsharina Ismail, Abdul Rahman Omar, Md Zuki Abu bakar, Maznah Ismail | Journal of Nutrition & Intermediary Metabolism |
| Rainbow trout exposed to benzo[a]pyrene yields conserved microRNA binding sites in DNA methyltransferases across 500 million years of evolution | Kuc C, Richard D, Johnson S et al | Scientific Reports |
| Reproductive effects linked to DNA methylation in male zebrafish chronically exposed to environmentally relevant concentrations of di-(2-ethylhexyl) phthalate. | Ma YB, Jia PP, Junaid M, Yang L, Lu CJ, Pei DS | Environ Pollut |
| Aspects of silver tolerance in bacteria: IR spectral changes and epigenetic clues. | Gurbanov R, Simsek Ozek N, Tunçer S, Severcan F, Gozen AG | J Biophotonics |
| Folate modulates guanine-quadruplex frequency and DNA damage in Werner syndrome | Shirazi P, Leifert W, Fenech M, François M, | Mutation Research/Genetic Toxicology and Environmental Mutagenes |
| Detection of changes in DNA methylation patterns in Pyropia hait | Yu, C., Xu, K., Wang, W. et al | J Appl Phycol |
| FAM20C could be targeted by TET1 to promote odontoblastic differentiation potential of human dental pulp cells. | Li Q, Yi B, Feng Z, Meng R, Tian C, Xu Q | Cell Prolif |
| Understanding the influence of antipsychotic drugs on global methylation events and its relevance in treatment response. | Swathy B, Saradalekshmi KR, Nair IV, Nair C, Banerjee M | Epigenomics |
| Epigenetic modulation of Nrf2 and Ogg1 gene expression in testicular germ cells by methyl parathion exposure. | Hernandez-Cortes D, Alvarado-Cruz I, SolÃs-Heredia MJ, Quintanilla-Vega B | Toxicol Appl Pharmacol |
| Alterations in glucose concentrations affect DNA methylation at Lrg1 in an ex vivo rat cortical slice model of preterm brain injury. | Cartier J, Piyasena C, Sparrow SA, Boardman JP, Drake AJ | Eur J Neurosci |
| Differential DNA methylation and transcription profiles in date palm roots exposed to salinity. | Al-Harrasi I, Al-Yahyai R, Yaish MW | PLoS One |
| Profile of epigenetic mechanisms in lung tumors of patients with underlying chronic respiratory conditions. | Mateu-Jimenez M, Curull V, RodrÃguez-Fuster A, Aguiló R, Sánchez-Font A, Pijuan L, Gea J, Barreiro E | Clin Epigenetics |
| Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: reversal by cannabidiol. | da Silva VK, de Freitas BS, Dornelles VC, Kist LW, Bogo MR, Silva MC, Streck EL, Hallak JE, Zuardi AW, Crippa JAS, Schröder N | Brain Res Bull |
| Diagnostic Value of Circulating Free DNA Integrity and Global Methylation Status in Gall Bladder Carcinoma. | Kumari S, Husain N, Agarwal A, Neyaz A, Gupta S, Chaturvedi A, Lohani M, Sonkar AA | Pathol Oncol Res |
| Preeclampsia is associated with hypermethylation of IGF-1 promoter mediated by DNMT1 | Min Ma, Qiong-Jie Zhou, Yu Xiong, Bin Li, Xiao-Tian Li | Am J Transl Res |
| Maternal NO<sub>2</sub> exposure induces cardiac hypertrophy in male offspring via ROS-HIF-1α transcriptional regulation and aberrant DNA methylation modification of Csx/Nkx2.5. | Zhang Y, Yan W, Ji X, Yue H, Li G, Sang N | Arch Toxicol |
| Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states. | Bogoi RN, de Pablo A, Valencia E, MartÃn-Carbonero L, Moreno V, Vilchez-Rueda HH, Asensi V, Rodriguez R, Toledano V, Rodés B | Clin Epigenetics |
| Curcumol Controls Choriocarcinoma Stem-Like Cells Self-Renewal via Repression of DNA Methyltransferase (DNMT)- and Histone Deacetylase (HDAC)-Mediated Epigenetic Regulation. | Peng Z, Zhou W, Zhang C, Liu H, Zhang Y | Med Sci Monit |
| CB1R-Mediated Activation of Caspase-3 Causes Epigenetic and Neurobehavioral Abnormalities in Postnatal Ethanol-Exposed Mice | Shivakumar S, Nagaraja N., Madhu S, Vikram J, Delphine P, Abdullah K, Nagavedi U, Balapal B. | Front. Mol. Neurosci. |
| Methyl-Donor and Cofactor Nutrient Intakes in the First 2-3 Years and Global DNA Methylation at Age 4: A Prospective Cohort Study. | Taylor RM, Smith R, Collins CE, Mossman D, Wong-Brown MW, Chan EC, Evans TJ, Attia JR, Smith T, Butler T, Hure AJ | Nutrients |
| CRH/CRHR1 mediates prenatal synthetic glucocorticoid programming of depression-like behavior across 2 generations. | Xu YJ, Sheng H, Wu TW, Bao QY, Zheng Y, Zhang YM, Gong YX, Lu JQ, You ZD, Xia Y, Ni X | FASEB J |
| Integrated approach of eco-epigenetics and eco-metabolomics on the stress response of bisphenol-A exposure in the aquatic midge Chironomus riparius. | Lee SW, Chatterjee N, Im JE, Yoon D, Kim S, Choi J | Ecotoxicol Environ Saf |
| Expression of heterologous lycopene β-cyclase gene in flax can cause silencing of its endogenous counterpart by changes in gene-body methylation and in ABA homeostasis mechanism. | Boba A, Kostyn K, Preisner M, Wojtasik W, Szopa J, Kulma A | Plant Physiol Biochem |
| DNA is hypomethylated in circadian manifestations of Bruxism. | Oporto GH, Salazar LA | Oral Dis |
| Paternal physical exercise demethylates the hippocampal DNA of male pups without modifying the cognitive and physical development. | Mega F, de Meireles ALF, Piazza FV, Spindler C, Segabinazi E, Dos Santos Salvalaggio G, Achaval M, Marcuzzo S | Behav Brain Res |
| DNA methylcytosine dioxygenase ten-eleven translocation 2 enhances lipopolysaccharide-induced cytokine expression in human dental pulp cells by regulating MyD88 hydroxymethylation. | Wang X, Feng Z, Li Q, Yi B, Xu Q | Cell Tissue Res |
| Does Dietary Provision of Guanidinoacetic Acid Induce Global DNA Hypomethylation in Healthy Men and Women? | Ostojic SM, Mojsin M, Drid P, Vranes M | Lifestyle Genom |
| Placental miR-340 mediates vulnerability to activity based anorexia in mice. | Schroeder M, Jakovcevski M, Polacheck T, Drori Y, Luoni A, Röh S, Zaugg J, Ben-Dor S, Albrecht C, Chen A | Nat Commun |
| Obesity in mares promotes uterine inflammation and alters embryo lipid fingerprints and homeostasis. | Sessions-Bresnahan DR, Heuberger AL, Carnevale EM | Biol Reprod |
| Evidence of Neurobiological Changes in the Presymptomatic PINK1 Knockout Rat. | Ferris CF, Morrison TR, Iriah S, Malmberg S, Kulkarni P, Hartner JC, Trivedi M | J Parkinsons Dis |
| BIX-01294 promotes the differentiation of adipose mesenchymal stem cells into adipocytes and neural cells in Arbas Cashmere goats | Qing Wang, Xiao Wang, Defang Lai, Jin Deng, Zhuang Hou, Hao Liang, Dongjun Liu | Research in Veterinary Science |
| Global DNA methylation since early infancy to adulthood in the offspring of women with polycystic ovary syndrome (PCOS) | Recabarren, S et al. | Endocrine Abstracts |
| Vorinostat Combined with DNMTi Epigenetically Controls the Proliferation of Lung Cancer Cells | Hussein Sabit, Mostafa Fathy, Shimaa E. Abdel-Ghany, Osama A. M. Said, Mokhtar M. El-Zawahry | ISJR |
| BIX-01294 promotes the differentiation of adipose mesenchymal stem cells into adipocytes and neural cells in Arbas Cashmere goats. | Wang Q, Wang X, Lai D, Deng J, Hou Z, Liang H, Liu D | Res Vet Sci |
| Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression. | Cimmino L, Dolgalev I, Wang Y, Yoshimi A, Martin GH, Wang J, Ng V, Xia B, Witkowski MT, Mitchell-Flack M, Grillo I, Bakogianni S, Ndiaye-Lobry D, MartÃn MT, Guillamot M, Banh RS, Xu M, Figueroa ME, Dickins RA, Abdel-Wahab O, Park CY, Tsirigos A, Neel BG, Aifantis I | Cell |
| Methylation of Cdkn1c may involve in the regulation of tooth development through cell cycle inhibition. | Li Q, Guo Y, Yao M, Li J, Chen Y, Liu Q, Chen Y, Zeng Y, Ji B, Feng Y | J Mol Histol |
| Determination of 5-Metylcytosine, 5-Hydroxymethylcytosine, and 5-Formylcytosine Expression in Mobile and Immobile Sperm From One Ejaculation: Analysis of Relationsips With Sperm Properties using Partial Least Square Regression | M Katayama, S Kaneko, T Tsukimura, K. Takamatsu, T. Togawa | Indian Journal of Research |
| The regulation of skeletal muscle fiber-type composition by betaine is associated with NFATc1/MyoD. | Du J, Shen L, Zhang P, Tan Z, Cheng X, Luo J, Zhao X, Yang Q, Gu H, Jiang A, Ma J, Tang Q, Jin L, Shuai S, Li M, Jiang Y, Tang G, Bai L, Li X, Wang J, Zhang S, Zhu L | J Mol Med (Berl) |
| CircIBTK inhibits DNA demethylation and activation of AKT signaling pathway via miR-29b in peripheral blood mononuclear cells in systemic lupus erythematosus. | Wang X, Zhang C, Wu Z, Chen Y, Shi W | Arthritis Res Ther |
| Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss | Ai-hua Wu, Dong-yu Yang, Yu-dong Liu, Xin Chen, Xu-long Chen, Shan Lu,Shi-ling Chen | Current Medical Science |
| α-ketoglutarate dehydrogenase inhibition counteracts breast cancer-associated lung metastasis. | Atlante S, Visintin A, Marini E, Savoia M, Dianzani C, Giorgis M, Sürün D, Maione F, Schnütgen F, Farsetti A, Zeiher AM, Bertinaria M, Giraudo E, Spallotta F, Cencioni C, Gaetano C | Cell Death Dis |
| Studying the frequency of aberrant DNA methylation of APC, P14, and E-cadherin genes in HCV-related hepatocarcinogenesis. | Mekky MA, Salama RH, Abdel-Aal MF, Ghaliony MA, Zaky S | Cancer Biomark |
| Urea cycle dysregulation in non-alcoholic fatty liver disease. | De Chiara F, Heebøll S, Marrone G, Montoliu C, Hamilton-Dutoit S, Ferrandez A, Andreola F, Rombouts K, Grønbæk H, Felipo V, Gracia-Sancho J, Mookerjee RP, Vilstrup H, Jalan R, Thomsen KL | J Hepatol |
| Identification of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome-associated DNA methylation patterns. | Trivedi MS, Oltra E, Sarria L, Rose N, Beljanski V, Fletcher MA, Klimas NG, Nathanson L | PLoS One |
| The detrimental effects of glucocorticoids exposure during pregnancy on offspring's cardiac functions mediated by hypermethylation of bone morphogenetic protein-4. | Peng J, Zhou Y, Zhang Z, Wang Z, Gao L, Zhang X, Fang Z, Li G, Chen H, Yang H, Gao L | Cell Death Dis |
| SIRT1 Activation Disrupts Maintenance of Myelodysplastic Syndrome Stem and Progenitor Cells by Restoring TET2 Function. | Sun J, He X, Zhu Y, Ding Z, Dong H, Feng Y, Du J, Wang H, Wu X, Zhang L, Yu X, Lin A, McDonald T, Zhao D, Wu H, Hua WK, Zhang B, Feng L, Tohyama K, Bhatia R, Oberdoerffer P, Chung YJ, Aplan PD, Boultwood J, Pellagatti A, Khaled S, Kortylewski M, Pichiorri F, Kuo YH, Carlesso N, Marcucci G, Jin H, Li L | Cell Stem Cell |
| Gestational chronodisruption leads to persistent changes in the rat fetal and adult adrenal clock and function. | Salazar ER, Richter HG, Spichiger C, Mendez N, Halabi D, Vergara K, Alonso IP, Corvalán FA, Azpeleta C, Seron-Ferre M, Torres-Farfan C | J Physiol |
| Sex dependent impact of gestational stress on predisposition to eating disorders and metabolic disease | Schroeder M | Molecular Metabolism |
| Environmental Enrichment Improves Cognitive Deficits, AD Hallmarks and Epigenetic Alterations Presented in 5xFAD Mouse Model. | Griñán-Ferré C, Izquierdo V, Otero E, Puigoriol-Illamola D, Corpas R, Sanfeliu C, Ortuño-Sahagún D, Pallàs M | Front Cell Neurosci |
| Arbuscular mycorrhizal fungi change host plant DNA methylation systemically. | Varga S, Soulsbury CD | Plant Biol (Stuttg) |
| 1,25-Dihydroxyvitamin D3 increases the methionine cycle, CD4+ T cell DNA methylation and Helios+Foxp3+ T regulatory cells to reverse autoimmune neurodegenerative disease | Moore J,Hubler S,Nelson C, Nashold F, Spanier J, Hayes C | Journal of Neuroimmunology |
| Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells. | Stone OA, El-Brolosy M, Wilhelm K, Liu X, Romão AM, Grillo E, Lai JKH, Günther S, Jeratsch S, Kuenne C, Lee IC, Braun T, Santoro MM, Locasale JW, Potente M, Stainier DYR | Nat Commun |
| Dynamic alterations in methylation of global DNA and growth-related genes in large yellow croaker (Larimichthys crocea) in response to starvation stress. | Zhang Y, Shen W, Cao M, Li J, Zheng B, Lou Z, Qian B, Xue L | Comp Biochem Physiol B Biochem Mol Biol |
| Dexamethasone-induced inhibition of miR-132 via methylation promotes TGF-β-driven progression of pancreatic cancer. | Abukiwan A, Nwaeburu CC, Bauer N, Zhao Z, Liu L, Gladkich J, Gross W, Benner A, Strobel O, Fellenberg J, Herr I | Int J Oncol |
| The cytotoxic chemotherapeutic agent Bleomycin increases cellular proliferation and pluripotency: A study on hAFSCs | Upadhyaya P, et al. | Research Gate |
| Epigenetic Modifications Induced by Submillimeter Wave Exposure | Cantu J, Peralta X, Cerna C, Echchzadda I. | IEEE |
| Paternal physical exercise modulates global DNA methylation status in the hippocampus of male rat offspring. | Spindler C, Segabinazi E, Meireles ALF, Piazza FV, Mega F, Dos Santos Salvalaggio G, Achaval M, Elsner VR, Marcuzzo S | Neural Regen Res |
| Deciphering the molecular effects of romidepsin on germ cell tumours: DHRS2 is involved in cell cycle arrest but not apoptosis or induction of romidepsin effectors. | Nettersheim D, Berger D, Jostes S, Skowron M, Schorle H | J Cell Mol Med |
| Coral epigenetic responses to nutrient stress: Histone H2A.X phosphorylation dynamics and DNA methylation in the staghorn coral Acropora cervicornis | Rodriguezâ€Casariego J. et al | Ecology and Evolution |
| Distribution of 5-methylcytosine and 5-hydroxymethylcytosine in bovine fetal tissue of the placenta | Mendonça A.S et al. | Pesq. Vet. Bras. |
| Blueberry anthocyanin alleviate perfluorooctanoic acid-induced toxicity in planarian (Dugesia japonica) by regulating oxidative stress biomarkers, ATP contents, DNA methylation and mRNA expression | Zhang J et al. | Environmental Pollution |
| Supplementation of Juçara Berry (Euterpe edulis Mart.) Modulates Epigenetic Markers in Monocytes from Obese Adults: A Double-Blind Randomized Trial. | Santamarina AB, Jamar G, Mennitti LV, de Cássia César H, de Rosso VV, Vasconcelos JR, Oyama LM, Pisani LP | Nutrients |
| MTHFR gene specific and global methylation patterns in normal pregnancy: A pilot study (India) | Mishra J et al. | Meta Gene |
| The effect of glutamate-induced excitotoxicity on DNA methylation in astrocytes in a new in vitro neuron-astrocyte-endothelium co-culture system. | Zhao H, Sun P, Fan T, Yang X, Zheng T, Sun C | Biochem Biophys Res Commun |
| Perinatal exposure to the SSRI paroxetine alters the methylome landscape of the developing dentate gyrus. | Glover ME, McCoy CR, Shupe E, Unroe K, Jackson NL, Clinton SM | Eur J Neurosci |
| Transcriptome reprogramming, epigenetic modifications and alternative splicing orchestrate the tomato root response to the beneficial fungus <i>Trichoderma harzianum</i>. | De Palma M, Salzano M, Villano C, Aversano R, Lorito M, Ruocco M, Docimo T, Piccinelli AL, D'Agostino N, Tucci M | Hortic Res |
| IDH3α regulates one-carbon metabolism in glioblastoma. | May JL, Kouri FM, Hurley LA, Liu J, Tommasini-Ghelfi S, Ji Y, Gao P, Calvert AE, Lee A, Chandel NS, Davuluri RV, Horbinski CM, Locasale JW, Stegh AH | Sci Adv |
| Modulation of Epigenetic Profiles in Traffic Workers Exposed to Car Fumes in Egypt | Shaat R. et al | Mol Biol |
| Association of BER and NER pathway polymorphism haplotypes and micronucleus frequencies with global DNA methylation in benzene-exposed workers of China: Effects of DNA repair genes polymorphisms on genetic damage | Zhang G. et al. | Mutation Research/Genetic Toxicology and Environmental Mutagenes |
| Distribution of 5-methylcytosine and 5-hydroxymethylcytosine in bovine fetal tissue of the placenta | Mendonça A.S, Braga T.F, Melo E.O, Dode M.A.N, Franco M.M | Pesq. Vet. Bras. |
| Early life alcohol exposure primes hypothalamic microglia to later-life hypersensitivity to immune stress: possible epigenetic mechanism. | Chastain LG, Franklin T, Gangisetty O, Cabrera MA, Mukherjee S, Shrivastava P, Jabbar S, Sarkar DK | Neuropsychopharmacology |
| The global DNA and RNA methylation and their reversal in lung under different concentration exposure of ambient air particulate matter in mice. | Li Z, Li N, Guo C, Li X, Qian Y, Yang Y, Wei Y | Ecotoxicol Environ Saf |
| Epigenetic mechanisms mediate the experimental evolution of resistance against parasitic fungi in the greater wax moth Galleria mellonella. | Mukherjee K, Dubovskiy I, Grizanova E, Lehmann R, Vilcinskas A | Sci Rep |
| Methionine Attenuates Lipopolysaccharide-Induced Inflammatory Responses via DNA Methylation in Macrophages | Ji J, Xu Y, Zheng M, Luo C, Lei H, Qu H, Shu D | ACS Omega |
| N-acetylcysteine alleviated bisphenol A-induced testicular DNA hypermethylation of rare minnow (Gobiocypris rarus) by increasing cysteine contents. | Yuan C, Wang L, Zhu L, Ran B, Xue X, Wang Z | Ecotoxicol Environ Saf |
| Consequences of Artificial Light at Night: The Linkage between Chasing Darkness Away and Epigenetic Modifications | Haim A., Boynao S., Zubidat A.E. | Epigenetics |
| Different effects of titanium dioxide nanoparticles instillation in young and adult mice on DNA methylation related with lung inflammation and fibrosis. | Ma Y, Guo Y, Ye H, Huang K, Lv Z, Ke Y | Ecotoxicol Environ Saf |
| Differential regulation of hepatic transcription factors in the Wistar rat offspring born to dams fed folic acid, vitamin B12 deficient diets and supplemented with omega-3 fatty acids. | Meher A, Joshi A, Joshi S | PLoS One |
| E2F1 mediates the downregulation of POLD1 in replicative senescence. | Gao S, Song Q, Liu J, Zhang X, Ji X, Wang P | Cell Mol Life Sci |
| Maternal Resveratrol Supplementation Prevents Cognitive Decline in Senescent Mice Offspring. | Izquierdo V, Palomera-Ãvalos V, López-Ruiz S, Canudas AM, Pallà s M, Griñán-Ferré C | Int J Mol Sci |
| Genetic and epigenetic alterations induced by the small-molecule panobinostat: A mechanistic study at the chromosome and gene levels. | Al-Hamamah MA, Alotaibi MR, Ahmad SF, Ansari MA, Attia MSM, Nadeem A, Bakheet SA, As Sobeai HM, Attia SM | DNA Repair (Amst) |
| Altered metabolic and hormonal responses in male rats exposed to acute bright light-at-night associated with global DNA hypo-methylation. | Yonis M, Haim A, Zubidat AE | J Photochem Photobiol B |
| Alterations in DNA Methylation Status Associated with Gulf War Illness. | Trivedi MS, Abreu MM, Sarria L, Rose N, Ahmed N, Beljanski V, Fletcher MA, Klimas NG, Nathanson L | DNA Cell Biol |
| Alterations in global DNA methylation and metabolism-related genes caused by zearalenone in MCF7 and MCF10F cells. | Karaman EF, Ozden S | Mycotoxin Res |
| Genetic, epigenetic, and developmental toxicity of Chironomus riparius raised in metal-contaminated field sediments: A multi-generational study with arsenic as a second challenge. | Im J, Chatterjee N, Choi J | Sci Total Environ |
| Myeloid-derived suppressor cells endow stem-like qualities to multiple myeloma cells by inducing piRNA-823 expression and DNMT3B activation. | Ai L, Mu S, Sun C, Fan F, Yan H, Qin Y, Cui G, Wang Y, Guo T, Mei H, Wang H, Hu Y | Mol Cancer |
| Insights into Salt Stress-Induced Biochemical, Molecular and Epigenetic Regulation of Spatial Responses in Pigeonpea (Cajanus cajan L.) | Awana, M., Yadav, K., Rani, K. et al. | Journal of Plant Growth Regulation |
| Association between methylation of DNA damage response-related genes and DNA damage in hepatocytes of rats following subchronic exposure to vinyl chloride | Qui Y, Xu Z, Qang Q, et. al. | Chemosphere |
| Assessment of epigenetic changes and oxidative DNA damage in rat pups exposed to polychlorinated biphenyls and the protective effect of curcumin in the prenatal period. | Doğan HO, Alçiğir ME | J Basic Clin Physiol Pharmacol |
| Epigenetic regulation of regulatory T cells in patients with abdominal aortic aneurysm. | Xia Q, Zhang J, Han Y, Zhang X, Jiang H, Lun Y, Wu X, Gang Q, Liu Z, Böckler D, Duan Z, Xin S | FEBS Open Bio |
| Deciphering the Elevated Lipid via CD36 in Mantle Cell Lymphoma with Bortezomib Resistance Using Synchrotron-Based Fourier Transform Infrared Spectroscopy of Single Cells. | Luanpitpong S, Janan M, Thumanu K, Poohadsuan J, Rodboon N, Klaihmon P, Issaragrisil S | Cancers (Basel) |
| Global DNA Methylation in the Limbic System of Cattle | Cantrell B., Lachance H., Murdoch B., Sjoquist J., Funston R., Weaber R., McKay, S. | Epigenomes |
| Thyroid Hormone Protects Primary Cortical Neurons Exposed to Hypoxia By Reducing DNA Methylation and Apoptosis. | Li J, Abe K, Milanesi A, Liu YY, Brent GA | Endocrinology |
| Arsenic inhibited cholesterol efflux of THP-1 macrophages via ROS-mediated ABCA1 hypermethylation. | Song Y, Zhou T, Zong Y, Gu B, Tan X, Yang L | Toxicology |
| Quercetin modifies 5'CpG promoter methylation and reactivates various tumor suppressor genes by modulating epigenetic marks in human cervical cancer cells. | Kedhari Sundaram M, Hussain A, Haque S, Raina R, Afroze N | J Cell Biochem |
| Prenatal and ancestral exposure to di(2-ethylhexyl) phthalate alters gene expression and DNA methylation in mouse ovaries. | Rattan S, Beers HK, Kannan A, Ramakrishnan A, Brehm E, Bagchi I, Irudayaraj JMK, Flaws JA | Toxicol Appl Pharmacol |
| Amplified electrochemical immunoassay for 5-methylcytosine using a nanocomposite prepared from graphene oxide, magnetite nanoparticles and β-cyclodextrin. | Zhou Y, Jiang W, Wu H, Liu F, Yin H, Lu N, Ai S | Mikrochim Acta |
| DNA methylation is involved in pro-inflammatory cytokines expression in T-2 toxin-induced liver injury. | Liu A, Sun Y, Wang X, Ihsan A, Tao Y, Chen D, Peng D, Wu Q, Wang X, Yuan Z | Food Chem Toxicol |
| Myc Is Required for Adaptive ß-Cell Replication in Young Mice but Is not Sufficient in One-Year-Old Mice Fed with a High-Fat Diet. | Rosselot C, Kumar A, Lakshmipathi J, Zhang P, Lu G, Katz LS, Prochownik EV, Stewart AF, Lambertini L, Scott DK, Garcia-Ocaña A | Diabetes |
| miR‑143 acts as a novel Big mitogen‑activated protein kinase 1 suppressor and may inhibit invasion of glioma | Chen, W., Lang, Z., Ren, C., Yang, P., Zhang, B | Oncology Reports |
| Pharmacological manipulation of DNA methylation normalizes maternal behavior, DNA methylation, and gene expression in dams with a history of maltreatment. | Keller SM, Doherty TS, Roth TL | Sci Rep |
| DNA methylation and RASSF4 expression are involved in T-2 toxin-induced hepatotoxicity. | Liu A, Xu X, Hou R, Badawy S, Tao Y, Chen D, Ihsan A, Wang X, Wu Q, Yuan Z | Toxicology |
| Methylation, sugar puckering and Z-form status of DNA from a heavy metal-acclimated freshwater Gordonia sp. | Gurbanov R, Tunçer S, Mingu S, Severcan F, Gozen AG | J Photochem Photobiol B |
| RNA methylomes reveal the m<sup>6</sup>A-mediated regulation of DNA demethylase gene SlDML2 in tomato fruit ripening. | Zhou L, Tian S, Qin G | Genome Biol |
| Aging Triggers H3K27 Trimethylation Hoarding in the Chromatin of Nothobranchius Furzeri Skeletal Muscle | Cencioni, C et. al. | Preprints |
| A Yap-Myc-Sox2-p53 Regulatory Network Dictates Metabolic Homeostasis and Differentiation in Kras-Driven Pancreatic Ductal Adenocarcinomas. | Murakami S, Nemazanyy I, White SM, Chen H, Nguyen CDK, Graham GT, Saur D, Pende M, Yi C | Dev Cell |
| Mercury Concentration, DNA Methylation, and Mitochondrial DNA Damage in Olive Ridley Sea Turtle Embryos With Schistosomus Reflexus Syndrome. | MartÃn-Del-Campo R, Bárcenas-Ibarra A, Lund G, RodrÃguez-RÃos D, Yong-Villalobos L, GarcÃa-Hernández J, GarcÃa-Gasca A | Vet Pathol |
| Effects of Maternal Physical Exercise on Global DNA Methylation and Hippocampal Plasticity of Rat Male Offspring. | Segabinazi E, Spindler C, de Meireles ALF, Piazza FV, Mega F, Dos Santos Salvalaggio G, Achaval M, Marcuzzo S | Neuroscience |
| Exposure to Maghemite Nanoparticles Induces Epigenetic Alterations in Human Submandibular Gland Cells. | Bonadio RS, Cunha MCPCD, Longo JPF, Azevedo RB, PoÇas-Fonseca MJ | J Nanosci Nanotechnol |
| Early exposure to a methyl donor supplemented diet and the development of repetitive motor behavior in a mouse model. | Muehlmann AM, Bliznyuk N, Duerr I, Yang TP, Lewis MH | Dev Psychobiol |
| Genetic and epigenetic modifications induced by chemotherapeutic drugs: human amniotic fluid stem cells as an in-vitro model. | Upadhyaya P, Di Serafino A, Sorino L, Ballerini P, Marchisio M, Pierdomenico L, Stuppia L, Antonucci I | BMC Med Genomics |
| Association of BER and NER pathway polymorphism haplotypes and micronucleus frequencies with global DNA methylation in benzene-exposed workers of China: Effects of DNA repair genes polymorphisms on genetic damage. | Zhang GH, Ren JC, Luo M, Cui J, Du Y, Yang D, Cui S, Wang X, Wu W, Cao J, Xia ZL | Mutat Res Genet Toxicol Environ Mutagen |
| Effect of chelating and antioxidant agents on morphology and DNA Methylation in Freeze-drying rabbit (Oryctolagus cuniculus) spermatozoa. | Mercati F, Domingo P, Pasquariello R, Dall'Aglio C, Di Michele A, Forti K, Cocci P, Boiti C, Gil L, Zerani M, Maranesi M | Reprod Domest Anim |
| Uridine Prevents Negative Effects of OXPHOS Xenobiotics on Dopaminergic Neuronal Differentiation. | Iglesias E, Bayona-Bafaluy MP, Pesini A, Garrido-Pérez N, Meade P, Gaudó P, Jiménez-Salvador I, Montoya J, Ruiz-Pesini E | Cells |
| MiR-29b interacts with IFN-γ and induces DNA hypomethylation in CD4<sup>+</sup> T cells of oral lichen planus. | Zhang J, Chen GY, Wang F, Zhou G | Int J Biol Macromol |
| Methylation-related metabolic effects of D4 dopamine receptor expression and activation. | Hodgson NW, Waly MI, Trivedi MS, Power-Charnitsky VA, Deth RC | Transl Psychiatry |
| Independent effect of main components in particulate matter on DNA methylation and DNA methyltransferase: A molecular epidemiology study. | Wang Y, Wang T, Xu M, Yu H, Ding C, Wang Z, Pan X, Li Y, Niu Y, Yan R, Song J, Yan H, Dai Y, Sun Z, Su W, Duan H | Environ Int |
| DNA Methylation Profile of <i>β-1,3-Glucanase</i> and <i>Chitinase</i> Genes in Flax Shows Specificity Towards <i>Fusarium Oxysporum</i> Strains Differing in Pathogenicity. | Wojtasik W, Boba A, Preisner M, Kostyn K, Szopa J, Kulma A | Microorganisms |
| Genistein Modulates Signaling Pathways and Targets Several Epigenetic Markers in HeLa Cells. | Sundaram MK, Unni S, Somvanshi P, Bhardwaj T, Mandal RK, Hussain A, Haque S | Genes (Basel) |
| Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters. | Laqqan M, Ahmed I, Yasin M, Hammadeh ME, Maged Y | Andrologia |
| Associations between metal exposure and global DNA methylation in potentially affected people in E-Waste recycling sites in Taizhou City, China | Li Z, et al. | Science of The Total Environment |
| miR-543 regulates the epigenetic landscape of myelofibrosis by targeting TET1 and TET2 | Fuentes-Mattei, E et. al | JCI Insight |
| Suicide Epigenetics, a Review of Recent Progress | Cheung S et al. | Journal of Affective Disorders |
| Interleukin 1β and Prostaglandin E2 affect expression of DNA methylating and demethylating enzymes in human gingival fibroblasts. | Seutter S, Winfield J, Esbitt A, Snyder S, Magner A, Kim K, Carcuffe C, Schmoyer J, Kamrani P, Mercando J, Shamseddin SM, Green K, Borghaei RC | Int Immunopharmacol |
| The Long-Term Impact of Mild Traumatic Brain Injuries on Multiple Functional Outcomes and Epigenetics: A Pilot Study with College Students | Lee, H et. al. | Preprints |
| Global DNA methylation and cognitive and behavioral outcomes at 4 years of age: A cross-sectional study. | Taylor RM, Smith R, Collins CE, Mossman D, Wong-Brown MW, Chan EC, Evans TJ, Attia JR, Buckley N, Drysdale K, Smith T, Butler T, Hure AJ | Brain Behav |
| Evaluation of the epigenetic alterations and gene expression levels of HepG2 cells exposed to zearalenone and α-zearalenol. | Karaman EF, Zeybel M, Ozden S | Toxicol Lett |
| Qian Yang Yu Yin Granule protects against hypertension -induced renal injury in spontaneously hypertensive rats and inhibits the proliferation of HEK293T through NNMT -mediated epigenetic mechanism. | Zhang SF, Mao XJ, Jiang WM, Fang ZY | J Ethnopharmacol |
| Identification of genetic features associated with fine particulate matter (PM2.5) modulated DNA damage using improved random forest analysis. | You D, Qin N, Zhang M, Dai J, Du M, Wei Y, Zhang R, Hu Z, Christiani DC, Zhao Y, Chen F | Gene |
| piRNA-63076 contributes to pulmonary arterial smooth muscle cell proliferation through acyl-CoA dehydrogenase. | Ma C, Zhang L, Wang X, He S, Bai J, Li Q, Zhang M, Zhang C, Yu X, Zhang J, Xin W, Li Y, Zhu D | J Cell Mol Med |
| Exposure to low doses of inorganic arsenic induces transgenerational changes on behavioral and epigenetic markers in zebrafish (Danio rerio). | Valles S, Hernández-Sánchez J, Dipp VR, Huerta-González D, Olivares-Bañuelos TN, González-Fraga J, Bardullas U | Toxicol Appl Pharmacol |
| DNA methylation and histone acetylation changes to cytochrome P450 2E1 regulation in normal aging and impact on rates of drug metabolism in the liver. | Kronfol MM, Jahr FM, Dozmorov MG, Phansalkar PS, Xie LY, Aberg KA, McRae M, Price ET, Slattum PW, Gerk PM, McClay JL | Geroscience |
| Early-Life Stress Induced Epigenetic Changes of Corticotropin-Releasing Factor Gene in Anorexic Low Body Weight-Selected Chicks. | Xiao Y, Wang J, Siegel PB, Cline MA, Gilbert ER | Life (Basel) |
| Regulation of DNA methylation signatures on NF-κB and STAT3 pathway genes and TET activity in cigarette smoke extract-challenged cells/COPD exacerbation model in vitro. | Kaur G, Batra S | Cell Biol Toxicol |
| Pharmacological DNA Demethylation Weakens Inhibitory Synapses in the Auditory Cortex and Re-opens the Critical Period for Frequency Map Plasticity. | Schwartz BA, Wang W, Bao S | Neuroscience |
| The role of cyadox and recombinant growth hormone (rGH) on the promotion of growth through epigenetics | Liu A, et. al. | Research Square |
| Dietary exposure of deoxynivalenol affected cytochrome P450 and growth related-gene expression via DNA methylation in piglet liver | Liu A, et. al. | Research Square |
| Perinatal nicotine exposure-induced transgenerational asthma: Effects of reexposure in F1 gestation. | Liu J, Yu C, Doherty TM, Akbari O, Allard P, Rehan VK | FASEB J |
| Ursodeoxycholic acid improves feto-placental and offspring metabolic outcomes in hypercholanemic pregnancy. | Borges Manna L, Papacleovoulou G, Flaviani F, Pataia V, Qadri A, Abu-Hayyeh S, McIlvride S, Jansen E, Dixon P, Chambers J, Vazquez-Lopez M, Wahlström A, Kitaba N, Marschall HU, Godfrey KM, Lillycrop K, Williamson C | Sci Rep |
| Mapping the Mitochondrial Regulation of Epigenetic Modifications in Association With Carcinogenic and Noncarcinogenic Polycyclic Aromatic Hydrocarbon Exposure. | Bhargava A, Kumari R, Khare S, Shandilya R, Gupta PK, Tiwari R, Rahman A, Chaudhury K, Goryacheva IY, Mishra PK | Int J Toxicol |
| DNA methylation patterns respond to thermal stress in the viviparous cockroach <i>Diploptera punctata</i>. | Villalba de la Peña M, Piskobulu V, Murgatroyd C, Hager R | Epigenetics |
| Dissecting major depression: The role of blood biomarkers and adverse childhood experiences in distinguishing clinical subgroups | Lo Iacono L, et. al. | Journal of Affective Disorders |
| A king and vassals’ tale: molecular signatures of clonal integration in Posidonia oceanica under chronic light shortage | Ruocco M, et. al. | Journal of Ecology |
| RACGAP1 Modulates ECT2-Dependent Mitochondrial Quality Control to Drive Breast Cancer Metastasis. | Ren K, Zhou D, Wang M, Li E, Hou C, Su Y, Zou Q, Zhou P, Liu X | Exp Cell Res |
| Epigallocatechin gallate inhibits HeLa cells by modulation of epigenetics and signaling pathways | Kedhari Sundaram M. et. al. | 3 Biotech |
| DNA methylation in adipocytes from visceral and subcutaneous adipose tissue influences insulin-signaling gene expression in obese individuals. | Cierzniak A, Pawelka D, Kaliszewski K, Rudnicki J, Dobosz T, Malodobra-Mazur M | Int J Obes (Lond) |
| Adipocyte-induced transdifferentiation of osteoblasts and its potential role in age-related bone loss. | Clabaut A, Grare C, Rolland-Valognes G, Letarouilly JG, Bourrier C, Andersen TL, Sikjær T, Rejnmark L, Ejersted C, Pastoureau P, Hardouin P, Sabatini M, Broux O | PLoS One |
| Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations under Maternal High-Fat Diet Intake: Epigenetic Inheritance over Generations. | Izquierdo V, Palomera-Ãvalos V, Pallà s M, Griñán-Ferré C | Int J Mol Sci |
| AtreMorine Treatment Regulates DNA Methylation in Neurodegenerative Disorders: Epigenetic and Pharmacogenetic Studies | MartÃnez-Iglesias, O et. al. | Current Pharmacogenomics and Personalized Medicine |
| Epigenetic biomarkers as tools for chemical hazard assessment: gene expression profiling using the model Danio rerio | Torres T, et. al. | Science of the Total Environment |
| Child Maltreatment: Adolescents' Psychiatric Sequels In The Light Of Oxytocin Receptor Gene SNP rs2254298 And Global DNA Methylation: A Case Control Study | Seif E. et. al. | Egyptian Journal of Forensic Science and Applied Toxicology |
| Methylenetetrahydrofolate reductase gene polymorphism, global DNA methylation and blood pressure: a population based study from North India. | Yadav S, Longkumer I, Joshi S, Saraswathy KN | BMC Med Genomics |
| Rhythmic regulation of DNA methylation factors and core-clock genes in brain structures activated by cocaine or sucrose | Saad L. et. al. | Molecular Neurobiology |
| Dual targeting of the epigenome via FACT complex and histone deacetylase is a potent treatment strategy for DIPG. | Ehteda A, Simon S, Franshaw L, Giorgi FM, Liu J, Joshi S, Rouaen JRC, Pang CNI, Pandher R, Mayoh C, Tang Y, Khan A, Ung C, Tolhurst O, Kankean A, Hayden E, Lehmann R, Shen S, Gopalakrishnan A, Trebilcock P, Gurova K, Gudkov AV, Norris MD, Haber M, Vittorio O, Tsoli M, Ziegler DS | Cell Rep |
| Effects of hypoxia on DNA hydroxymethylase Tet methylcytosine dioxygenase 2 in a KG‑1 human acute myeloid leukemia cell line and its mechanism | He, P. et. al. | Oncology Letters |
| Maternal choline supplementation in a rat model of periconceptional alcohol exposure: Impacts on the fetus and placenta. | Steane SE, Fielding AM, Kent NL, Andersen I, Browne DJ, Tejo EN, GÃ¥rdebjer EM, Kalisch-Smith JI, Sullivan MA, Moritz KM, Akison LK | Alcohol Clin Exp Res |
| Luteolin Causes 5'CpG Demethylation of the Promoters of TSGs and Modulates the Aberrant Histone Modifications, Restoring the Expression of TSGs in Human Cancer Cells. | Pramodh S, Raina R, Hussain A, Bagabir SA, Haque S, Raza ST, Ajmal MR, Behl S, Bhagavatula D | Int J Mol Sci |
| Deficiency of Tet3 in nucleus accumbens enhances fear generalization and anxiety-like behaviors in mice. | Fan BF, Hao B, Dai YD, Xue L, Shi YW, Liu L, Xuan SM, Yang N, Wang XG, Zhao H | Brain Pathol |
| Genome-wide alternation and effect of DNA methylation in the impairments of steroidogenesis and spermatogenesis after PM2.5 exposure | Zhang Z, Wang J, Shi F, Li Y, Zou P, Tang Y, Liu C, Wang Y, Ling X, Sun L, Liu C, Zhang Y, Gao F, Chen Q, Ao L, Han F, Liu J, Cao J | Environ Int |
| Associations of fertility parameters with fatty acids and DNA methylation in Mexican women undergoing in vitro fertilization | Zúñiga-Sánchez P, González-Ortega C, Cancino-Villarreal P, Martínez-Garza S, Molina-Torres J, Ramírez-Chávez E, Gutiérrez-Gutiérrez AM, Lund G, Zaina S | Int J Obes (Lond) |
| Using zebrafish embryo bioassays to identify chemicals modulating the regulation of the epigenome: a case study with simvastatin. | Torres T, Barros S, Neuparth T, Ruivo R, Santos MM | Environ Sci Pollut Res Int |
| G Protein-Coupled Receptor 37L1 Modulates Epigenetic Changes in Human Renal Proximal Tubule Cells. | Armando I, Cuevas S, Fan C, Kumar M, Izzi Z, Jose PA, Konkalmatt PR | Int J Mol Sci |
| Editorial: Epigenomic polymorphisms: The drivers of diversity and heterogeneity. | Dar TU, Akhter N, Dar SA | Front Genet |
| Neuroprotective Epigenetic Changes Induced by Maternal Treatment with an Inhibitor of Soluble Epoxide Hydrolase Prevents Early Alzheimer's Disease Neurodegeneration. | Bartra C, Irisarri A, Villoslada A, Corpas R, Aguirre S, GarcÃa-Lara E, Suñol C, Pallà s M, Griñán-Ferré C, Sanfeliu C | Int J Mol Sci |
| Genome-Wide Analysis on Transcriptome and Methylome in Prevention of Mammary Tumor Induced by Early Life Combined Botanicals. | Arora I, Li S, Crowley MR, Li Y, Tollefsbol TO | Cells |
| Genome-Wide Analysis on Transcriptome and Methylome in Prevention of Mammary Tumor Induced by Early Life Combined Botanicals. | Arora I, Li S, Crowley MR, Li Y, Tollefsbol TO | Cells |
| DNA Methylation as a Biomarker for Monitoring Disease Outcome in Patients with Hypovitaminosis and Neurological Disorders. | MartÃnez-Iglesias O, Naidoo V, Corzo L, Pego R, Seoane S, RodrÃguez S, Alcaraz M, Muñiz A, Cacabelos N, Cacabelos R | Genes (Basel) |
| Prenatal Environmental Stressors and DNA Methylation Levels in Placenta and Peripheral Tissues of Mothers and Neonates Evaluated by Applying Artificial Neural Networks. | Stoccoro A, Nicolì V, Coppedè F, Grossi E, Fedrizzi G, Menotta S, Lorenzoni F, Caretto M, Carmignani A, Pistolesi S, Burgio E, Fanos V, Migliore L | Genes (Basel) |
| Biochemical and Epigenetic Modulations under Drought: Remembering the Stress Tolerance Mechanism in Rice. | Kumar S, Seem K, Mohapatra T | Life (Basel) |
| Impact of waterpipe and tobacco cigarette smoking on global DNA methylation and nuclear proteins genes transcription in spermatozoa: a comparative investigation. | Laqqan MM, Al-Ghora SS, Yassin MM | Inhal Toxicol |
| DNMT3B alleviates liver steatosis induced by chronic low-grade LPS via inhibiting CIDEA expression. | Li Q, Wang W, Duan F, Wang Y, Chen S, Shi K, Xia Y, Li X, Gao Y, Li Q, Liu G | Cell Mol Gastroenterol Hepatol |
| DNA methylation on C5-Cytosine and N6-Adenine in the Bursaphelenchus xylophilus genome. | Liu Z, Li Y, Zhang X | BMC Genomics |
| Effects of Methionine Restriction from Different Sources on Sperm Quality in Aging Mice. | Wu Y, Li H, Miao Y, Peng J, Wei H | Nutrients |
| Cadmium-induced global DNA hypermethylation promoting mitochondrial dynamics dysregulation in hippocampal neurons. | Geng H, An Q, Song J, He D, Han H, Wang L | Environ Toxicol |
| Exposure to the extremely low-frequency electromagnetic field induces changes in the epigenetic regulation of gene expression in the endometrium. | Wydorski PJ, Kozlowska W, Zmijewska A, Franczak A | Theriogenology |
| Global DNA Methylation Levels Viz-a-Viz Genetic and Biochemical Variations in One Carbon Metabolic Pathway: An Exploratory Study from North India. | Chaudhary V, Bhattacharjee D, Devi NK, Saraswathy KN | Biochem Genet |
| Aerobic exercise alters DNA hydroxymethylation levels in an experimental rodent model of temporal lobe epilepsy. | Sint Jago SC, Bahabry R, Schreiber AM, Homola J, Ngyuen T, Meijia F, Allendorfer JB, Lubin FD | Epilepsy Behav Rep |
| Maternal dietary fatty acid composition and content prior to and during pregnancy and lactation influences serum profile, liver phenotype and hepatic miRNA expression in young male and female offspring. | Mennitti LV, de Souza EA, Santamarina AB, Sertorio MN, Jucá A, De Souza DV, Ribeiro DA, Pisani LP | J Nutr Biochem |
| A Lacticaseibacillus rhamnosus secretome induces immunoregulatory transcriptional, functional and immunometabolic signatures in human THP-1 monocytes. | Jeffrey MP, Saleem L, MacPherson CW, Tompkins TA, Clarke ST, Green-Johnson JM | Sci Rep |
| TNFα Induces DNA and Histone Hypomethylation and Pulmonary Artery Smooth Muscle Cell Proliferation Partly via Excessive Superoxide Formation. | Crosswhite P, Sun Z | Antioxidants (Basel) |
| The DNA methyltransferase inhibitor decitabine blunts the response to a high animal fat and protein diet in mice. | Flores-Sierra JJ, Muciño-Arellano MDR, Romo-Morales GDC, Sánchez-Palafox JE, Correa-Navarro VA, ColÃn-Castelán D, Pérez-Vázquez V, Rangel-Salazar R, Rivera-Bustamante R, de la Rocha C, RodrÃguez-RÃos D, Trejo-Saavedra DL, Molina-Torres J, RamÃrez-Chávez E, GarcÃa-Rojas NS, Winkler R, Lund G, Zaina S | J Lipid Res |
| The Role of Oxidative Stress and DNA Hydroxymethylation in the Pathogenesis of Benzo[a]pyrene-Impaired Reproductive Function in Male Mice. | Gan Y, Zhang X, Cai P, Zhao L, Liu K, Wang H, Xu D | Environ Toxicol |
| Therapeutic potential of tLyp-1-EV-shCTCF in inhibiting liver cancer stem cell self-renewal and immune escape via SALL3 modulation in hepatocellular carcinoma. | Zhu H, Xie Z | Transl Oncol |
| Buccal DNA global methylation and cognitive performance in stunted children under 5 years of age. | Handoyo Utomo AR, Yusnita Y, Sari SM, Ranakusuma OI, Bagaskara S, Sari W, Suciati Y, Nur Hidayati AP, Nihayah S, Putro CA, Nurainy N | J Biomed Res |
| Global DNA methylation level in spermatozoa is not associated with ICSI fertilization outcome and embryo quality in donor oocyte programme. | Pandya RK, Salian SR, Lakshmi VR, Uppangala S, Kalthur G, Gupta S, Adiga SK | Hum Fertil (Camb) |
| Enhancing intrinsic TGF-β signaling via heparan sulfate glycosaminoglycan regulation to promote mesenchymal stem cell capabilities and chondrogenesis for cartilage repair. | Chung PH, Lin FH, Liu IH | Int J Biol Macromol |
| Induction of FAM46C expression mediated by DNMT3A downregulation is involved in early-onset preeclampsia through gene body methylation. | Jia Y, Xie H, Wu S, Dong J, Ying H | Cell Signal |
| DNMT3a Downregulation Ttriggered Upregulation of GABA(A) Receptor in the mPFC Promotes Paclitaxel-Induced Pain and Anxiety in Male Mice. | Tian L, Li XH, Zhao YL, Yi HY, Liu XR, Yao R, Hou XM, Zhu X, Huo FQ, Chen T, Liang L | Adv Sci (Weinh) |
| DNMT1 inhibition improves the activity of memory-like natural killer cells by enhancing the level of autophagy. | Li Y, Guo C, Zhang F, Cheng S, Li Y, Luo S, Zeng Y, Zhao Y, Wu K | Mol Biol Rep |
| Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells. | Wells C, Pogribna M, Sharmah A, Paredes A, Word B, Patri AK, Lyn-Cook B, Hammons G | Nanomaterials (Basel) |
