脂质立方相（LCP）结晶已经发展成为膜蛋白结晶的一种重要方法，其中脂质单油酸甘油酯（Monoolein）是创建稳定LCP的首选。然而，在过去几年中，短链脂质7.7 MAG[4,7]、7.8 MAG[6-8]和7.9 MAG[5,7]变得越来越受欢迎。最近在将高黏度脂质立方相应用于连续飞秒晶体学（LCP-SFX）方面的进展[1-3]，通过以下方式进一步加速了LCP方法的成功：
- 将载有晶体的黏性LCP直接送入X射线自由电子激光（XFEL）光束中（与液体注射器相比，减少了样品消耗)；
- 利用在LCP中生长的固有小晶体；
- 避免了从LCP中进行棘手的晶体装载。
| LCP脂质 | 脂质结构 | 货号 | 规格 |
|---|---|---|---|
| Monoolein 9.9 MAG |  |
X-LCP-101 | 1 g |
| 7.7 MAG |  |
X-LCP-105 | 100 mg |
| 7.8 MAG |  |
X-LCP-106 | 100 mg |
| 7.9 MAG （Stable at low temperatures） |
 |
X-LCP-107 | 100 mg |
| Monopalmitolein 9.7 MAG |  |
X-LCP-102 | 1 g |
| Monovaccenin 11.7 MAG |  |
X-LCP-103 | 100 mg |
| Monoeicosenoin 11.9 MAG |  |
X-LCP-104 | 1 g |
JBScreen LCP旨在高效筛选LCP中的结晶条件。上述表格中的每种LCP脂质都能创建一个稳定的脂质立方相，可用于与JBScreen LCP进行结晶设置。其96种条件是通过对192种成功通过in meso方法结晶并产生结构的整合膜蛋白进行数据挖掘得出的[7]。该筛选按沉淀剂的浓度和类型排序，并且不含乙酸镉。
| 产品名称 | 货号 | 规格 |
| JBScreen LCP | CS-340 | 4×24 solutions (10 ml each) |
| JBScreen LCP HTS | CS-213L | 96 solutions (1,7 ml each) |
文献：
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