高效ChIP实验首选:EpiQuik™ ChIP试剂盒获275篇研究支持,5小时极速完成

EpiQuik™ 染色质免疫沉淀 (ChIP) 试剂盒是一整套优化的试剂,可通过便捷的微孔板形式进行染色质免疫沉淀 (ChIP)。该试剂盒为即用型试剂盒,提供成功进行 ChIP 实验所需的所有基本组分。EpiQuik™ ChIP 试剂盒适用于将免疫沉淀的特异性与定性和定量 PCR、ChIP-Seq 和 ChIP-on-chip 相结合。该染色质免疫沉淀 (ChIP) 试剂盒具有以下优点:

  • 快速简便的微孔板作流程,可在 5 小时内完成。
  • 条带微孔规格使分析更加灵活:手动或高通量。
  • 包括用于 DNA 纯化的色谱柱:节省大量时间并减少不必要的体力劳动。
  • 与所有基于 DNA 扩增的方法兼容。
  • 实现非常可靠和一致的分析条件。

 

产品名称 货号 规格
EpiQuik™ 染色质免疫沉淀 (ChIP) 试剂盒

EpiQuik Chromatin Immunoprecipitation (ChIP) Kit

P-2002 24 次反应

46 次反应

98 次反应

 

染色质免疫沉淀 (ChIP) 试剂盒 275篇文献引用:

标题 作者 杂志
Bosentan reverses the pro-fibrotic phenotype of systemic sclerosis dermal fibroblasts via increasing DNA binding ability of transcription factor Fli1. Akamata K, Asano Y, Aozasa N, Noda S, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Sato S Arthritis Res Ther
Apoptotic response through a high mobility box 1 protein-dependent mechanism in LPS/GalN-induced mouse liver failure and glycyrrhizin-mediated inhibition. Kuroda N, Inoue K, Ikeda T, Hara Y, Wake K, Sato T PLoS One
Cladosporol A, a new peroxisome proliferator-activated receptor γ (PPARγ) ligand, inhibits colorectal cancer cells proliferation through β-catenin/TCF pathway inactivation. Zurlo D, Assante G, Moricca S, Colantuoni V, Lupo A Biochim Biophys Acta
Hydrogen sulfide suppresses oxidized low-density lipoprotein (ox-LDL)-stimulated monocyte chemoattractant protein 1 generation from macrophages via the nuclear factor κB (NF-κB) pathway. Du J, Huang Y, Yan H, Zhang Q, Zhao M, Zhu M, Liu J, Chen SX, Bu D, Tang C, Jin H J Biol Chem
Interleukin-1 receptor antagonist induction as an additional mechanism for liver receptor homolog-1 to negatively regulate the hepatic acute phase response. Venteclef N, Delerive P J Biol Chem
Cloning and characterization of the rat lysyl oxidase gene promoter: identification of core promoter elements and functional nuclear factor I-binding sites. Gao S, Zhao Y, Kong L, Toselli P, Chou IN, Stone P, Li W J Biol Chem
AS1411 alters the localization of a complex containing protein arginine methyltransferase 5 and nucleolin. Teng Y, Girvan AC, Casson LK, Pierce WM Jr, Qian M, Thomas SD, Bates PJ Cancer Res
Functional roles of Fli-1, a member of the Ets family of transcription factors, in human breast malignancy. Sakurai T, Kondoh N, Arai M, Hamada J, Yamada T, Kihara-Negishi F, Izawa T, Ohno H, Yamamoto M, Oikawa T Cancer Sci
Human BSAP and BLIMP1 conform an autoregulatory feedback loop. Mora-López F, Reales E, Brieva JA, Campos-Caro A Blood
Transcriptional activation of p53 by Pitx1. Liu DX, Lobie PE Cell Death Differ
Regulation of anti-atherogenic apolipoprotein M gene expression by the orphan nuclear receptor LRH-1. Venteclef N, Haroniti A, Tousaint JJ, Talianidis I, Delerive P J Biol Chem
NFAT but not NF-kappaB is critical for transcriptional induction of the prosurvival gene A1 after IgE receptor activation in mast cells. Ullerås E, Karlberg M, Möller Westerberg C, Alfredsson J, Gerondakis S, Strasser A, Nilsson G Blood
MUC1 expression is regulated by DNA methylation and histone H3 lysine 9 modification in cancer cells. Yamada N, Nishida Y, Tsutsumida H, Hamada T, Goto M, Higashi M, Nomoto M, Yonezawa S Cancer Res
SPARC promoter hypermethylation in colorectal cancers can be reversed by 5-Aza-2'deoxycytidine to increase SPARC expression and improve therapy response. Cheetham S, Tang MJ, Mesak F, Kennecke H, Owen D, Tai IT Br J Cancer
Transcription of PRDM1, the master regulator for plasma cell differentiation, depends on an SP1/SP3/EGR-1 GC-box. Mora-López F, Pedreño-Horrillo N, Delgado-Pérez L, Brieva JA, Campos-Caro A Eur J Immunol
FOXO1 regulates L-Selectin and a network of human T cell homing molecules downstream of phosphatidylinositol 3-kinase. Fabre S, Carrette F, Chen J, Lang V, Semichon M, Denoyelle C, Lazar V, Cagnard N, Dubart-Kupperschmitt A, Mangeney M, Fruman DA, Bismuth G J Immunol
Characterization and functional analysis of cis-acting elements of the human farnesyl diphosphate synthetase (FDPS) gene 5' flanking region. Romanelli MG, Lorenzi P, Sangalli A, Diani E, Mottes M Genomics
IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation. Garaud S, Le Dantec C, Jousse-Joulin S, Hanrotel-Saliou C, Saraux A, Mageed RA, Youinou P, Renaudineau Y J Immunol
MeCP2/H3meK9 are involved in IL-6 gene silencing in pancreatic adenocarcinoma cell lines. Dandrea M, Donadelli M, Costanzo C, Scarpa A, Palmieri M Nucleic Acids Res
Thyrotropin receptor activation increases hyaluronan production in preadipocyte fibroblasts: contributory role in hyaluronan accumulation in thyroid dysfunction. Zhang L, Bowen T, Grennan-Jones F, Paddon C, Giles P, Webber J, Steadman R, Ludgate M J Biol Chem
Transcriptional activity of the murine retinol-binding protein gene is regulated by a multiprotein complex containing HMGA1, p54 nrb/NonO, protein-associated splicing factor (PSF) and steroidogenic factor 1 (SF1)/liver receptor homologue 1 (LRH-1). Bianconcini A, Lupo A, Capone S, Quadro L, Monti M, Zurlo D, Fucci A, Sabatino L, Brunetti A, Chiefari E, Gottesman ME, Blaner WS, Colantuoni V Int J Biochem Cell Biol
Glutaredoxin 1 regulates cigarette smoke-mediated lung inflammation through differential modulation of I{kappa}B kinases in mice: impact on histone acetylation. Chung S, Sundar IK, Yao H, Ho YS, Rahman I Am J Physiol Lung Cell Mol Physiol
Ets-1 promotes the progression of cerebral aneurysm by inducing the expression of MCP-1 in vascular smooth muscle cells. Aoki T, Kataoka H, Nishimura M, Ishibashi R, Morishita R, Miyamoto S Gene Ther
Bmi1 directly represses p21Waf1/Cip1 in Shh-induced proliferation of cerebellar granule cell progenitors. Subkhankulova T, Zhang X, Leung C, Marino S Mol Cell Neurosci
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1. Sánchez-Tilló E, Lázaro A, Torrent R, Cuatrecasas M, Vaquero EC, Castells A, Engel P, Postigo A Oncogene
Epigenetic regulation of myofibroblast differentiation by DNA methylation. Hu B, Gharaee-Kermani M, Wu Z, Phan SH Am J Pathol
Cortisol is involved in temperature-dependent sex determination in the Japanese flounder. Yamaguchi T, Yoshinaga N, Yazawa T, Gen K, Kitano T Endocrinology
Histone demethylase LSD1 regulates adipogenesis. Musri MM, Carmona MC, Hanzu FA, Kaliman P, Gomis R, Párrizas M J Biol Chem
Analysis of the Wnt/B-catenin/TCF4 pathway using SAGE, genome-wide microarray and promoter analysis: Identification of BRI3 and HSF2 as novel targets. Kavak E, Najafov A, Ozturk N, Seker T, Cavusoglu K, Aslan T, Duru AD, Saygili T, Hoxhaj G, Hiz MC, Unal DO, Birgül-Iyison N, Ozturk M, Koman A Cell Signal
Expression of MUC5AC, an early marker of pancreatobiliary cancer, is regulated by DNA methylation in the distal promoter region in cancer cells. Yamada N, Nishida Y, Yokoyama S, Tsutsumida H, Houjou I, Kitamoto S, Goto M, Higashi M, Yonezawa S J Hepatobiliary Pancreat Sci
Roles of Kruppel-like factor 4 in oesophageal epithelial cells in Barrett's epithelium development. Kazumori H, Ishihara S, Takahashi Y, Amano Y, Kinoshita Y Gut
miR-520b regulates migration of breast cancer cells by targeting hepatitis B X-interacting protein and interleukin-8. Hu N, Zhang J, Cui W, Kong G, Zhang S, Yue L, Bai X, Zhang Z, Zhang W, Zhang X, Ye L J Biol Chem
Thrombomodulin is silenced in malignant mesothelioma by a poly(ADP-ribose) polymerase-1-mediated epigenetic mechanism. Nocchi L, Tomasetti M, Amati M, Neuzil J, Santarelli L, Saccucci F J Biol Chem
CD5 promotes IL-10 production in chronic lymphocytic leukemia B cells through STAT3 and NFAT2 activation. Garaud S, Morva A, Lemoine S, Hillion S, Bordron A, Pers JO, Berthou C, Mageed RA, Renaudineau Y, Youinou P J Immunol
p45NF-E2 represses Gcm1 in trophoblast cells to regulate syncytium formation, placental vascularization and embryonic growth. Kashif M, Hellwig A, Kolleker A, Shahzad K, Wang H, Lang S, Wolter J, Thati M, Vinnikov I, Bierhaus A, Nawroth PP, Isermann B Development
Identification of transcriptional regulatory elements required for the Mup2 expression in circadian clock mutant mice. Cho YH, Kim D, Choi I, Bae K Biochem Biophys Res Commun
Efficient non-viral reprogramming of myoblasts to stemness with a single small molecule to generate cardiac progenitor cells. Pasha Z, Haider HKh, Ashraf M PLoS One
DNA methylation and histone modifications regulate de novo shoot regeneration in Arabidopsis by modulating WUSCHEL expression and auxin signaling. Li W, Liu H, Cheng ZJ, Su YH, Han HN, Zhang Y, Zhang XS PLoS Genet
Thyroid-specific gene expression in chondrocytes. Endo T, Kobayashi T Biochem Biophys Res Commun
MicroRNA-34a suppresses malignant transformation by targeting c-Myc transcriptional complexes in human renal cell carcinoma. Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Chang I, Tanaka Y, Gupta A, Dahiya R Carcinogenesis
MicroRNA-34a modulates c-Myc transcriptional complexes to suppress malignancy in human prostate cancer cells. Yamamura S, Saini S, Majid S, Hirata H, Ueno K, Deng G, Dahiya R PLoS One
Heat shock factor 1 regulates the expression of the TRPV1 gene in the rat preoptic-anterior hypothalamus area during lipopolysaccharide-induced fever. Fan-xin M, Li-mei S, Bei S, Xin Q, Yu Y, Yu C Exp Physiol
Epigenetic modulation of Homer1a transcription regulation in amygdala and hippocampus with pavlovian fear conditioning. Mahan AL, Mou L, Shah N, Hu JH, Worley PF, Ressler KJ J Neurosci
Gadd45a transcriptional induction elicited by the Aurora kinase inhibitor MK-0457 in Bcr-Abl-expressing cells is driven by Oct-1 transcription factor. Mancini M, Leo E, Aluigi M, Marcozzi C, Borsi E, Barbieri E, Santucci MA Leuk Res
Constitutive activation of c-Abl/protein kinase C-δ/Fli1 pathway in dermal fibroblasts derived from patients with localized scleroderma. Noda S, Asano Y, Akamata K, Aozasa N, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Sumida H, Yanaba K, Tada Y, Sugaya M, Kadono T, Sato S Br J Dermatol
Nerve growth factor-induced cell cycle reentry in newborn neurons is triggered by p38MAPK-dependent E2F4 phosphorylation. Morillo SM, Abanto EP, Román MJ, Frade JM Mol Cell Biol
The oncoprotein HBXIP uses two pathways to up-regulate S100A4 in promotion of growth and migration of breast cancer cells. Liu S, Li L, Zhang Y, Zhang Y, Zhao Y, You X, Lin Z, Zhang X, Ye L J Biol Chem
Elevation of highly up-regulated in liver cancer (HULC) by hepatitis B virus X protein promotes hepatoma cell proliferation via down-regulating p18. Du Y, Kong G, You X, Zhang S, Zhang T, Gao Y, Ye L, Zhang X J Biol Chem
Calcitonin gene-related peptide enhances experimental autoimmune encephalomyelitis by promoting Th17-cell functions. Mikami N, Watanabe K, Hashimoto N, Miyagi Y, Sueda K, Fukada S, Yamamoto H, Tsujikawa K Int Immunol
Cytoplasmatic compartmentalization by Bcr-Abl promotes TET2 loss-of-function in chronic myeloid leukemia. Mancini M, Veljkovic N, Leo E, Aluigi M, Borsi E, Galloni C, Iacobucci I, Barbieri E, Santucci MA J Cell Biochem
Hypoxia-response element (HRE)-directed transcriptional regulation of the rat lysyl oxidase gene in response to cobalt and cadmium. Gao S, Zhou J, Zhao Y, Toselli P, Li W Toxicol Sci
Histone deacetylase inhibition activates transgene expression from integration-defective lentiviral vectors in dividing and non-dividing cells. Pelascini LP, Janssen JM, Gonçalves MA Hum Gene Ther
The oncoprotein HBXIP activates transcriptional coregulatory protein LMO4 via Sp1 to promote proliferation of breast cancer cells. Yue L, Li L, Liu F, Hu N, Zhang W, Bai X, Li Y, Zhang Y, Fu L, Zhang X, Ye L Carcinogenesis
Hepatitis B virus X protein upregulates Lin28A/Lin28B through Sp-1/c-Myc to enhance the proliferation of hepatoma cells. You X, Liu F, Zhang T, Lv N, Liu Q, Shan C, Du Y, Kong G, Wang T, Ye L, Zhang X Oncogene
The oncoprotein HBXIP up-regulates Skp2 via activating transcription factor E2F1 to promote proliferation of breast cancer cells. Xu F, You X, Liu F, Shen X, Yao Y, Ye L, Zhang X Cancer Lett
Dual function of MIPS1 as a metabolic enzyme and transcriptional regulator. Latrasse D, Jégu T, Meng PH, Mazubert C, Hudik E, Delarue M, Charon C, Crespi M, Hirt H, Raynaud C, Bergounioux C, Benhamed M Nucleic Acids Res
Histone modifications in senescence-associated resistance to apoptosis by oxidative stress. Sanders YY, Liu H, Zhang X, Hecker L, Bernard K, Desai L, Liu G, Thannickal VJ Redox Biol
Calcitonin gene-related peptide and cyclic adenosine 5'-monophosphate/protein kinase A pathway promote IL-9 production in Th9 differentiation process. Mikami N, Miyagi Y, Sueda K, Takatsuji M, Fukada S, Yamamoto H, Tsujikawa K J Immunol
Nucleophosmin mutations alter its nucleolar localization by impairing G-quadruplex binding at ribosomal DNA. Chiarella S, De Cola A, Scaglione GL, Carletti E, Graziano V, Barcaroli D, Lo Sterzo C, Di Matteo A, Di Ilio C, Falini B, Arcovito A, De Laurenzi V, Federici L Nucleic Acids Res
Neurogenin3 cooperates with Foxa2 to autoactivate its own expression. Ejarque M, Cervantes S, Pujadas G, Tutusaus A, Sanchez L, Gasa R J Biol Chem
Epigenetic control of HNF-4a in colon carcinoma cells affects MUC4 expression and malignancy. Algamas-Dimantov A, Yehuda-Shnaidman E, Peri I, Schwartz B Cell Oncol (Dordr)
ZEB1 imposes a temporary stage-dependent inhibition of muscle gene expression and differentiation via CtBP-mediated transcriptional repression. Siles L, Sánchez-Tilló E, Lim JW, Darling DS, Kroll KL, Postigo A Mol Cell Biol
TNFa modulates Fibroblast Growth Factor Receptor 2 gene expression through the pRB/E2F1 pathway: identification of a non-canonical E2F binding motif. D'Amici S, Ceccarelli S, Vescarelli E, Romano F, Frati L, Marchese C, Angeloni A PLoS One
Histone demethylase KDM1A represses inflammatory gene expression in preadipocytes. Hanzu FA, Musri MM, Sánchez-Herrero A, Claret M, Esteban Y, Kaliman P, Gomis R, Párrizas M Obesity (Silver Spring)
The oncoprotein HBXIP upregulates PDGFB via activating transcription factor Sp1 to promote the proliferation of breast cancer cells. Zhang Y, Zhao Y, Li L, Shen Y, Cai X, Zhang X, Ye L Biochem Biophys Res Commun
BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation. Matsumoto T, Yamada A, Aizawa R, Suzuki D, Tsukasaki M, Suzuki W, Nakayama M, Maki K, Yamamoto M, Baba K, Kamijo R PLoS One
Divergent expression regulation of gonad development genes in medaka shows incomplete conservation of the downstream regulatory network of vertebrate sex determination. Herpin A, Adolfi MC, Nicol B, Hinzmann M, Schmidt C, Klughammer J, Engel M, Tanaka M, Guiguen Y, Schartl M Mol Biol Evol
Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1+ cells. Mancini M, Leo E, Takemaru K, Campi V, Borsi E, Castagnetti F, Gugliotta G, Santucci MA, Martinelli G Cell Signal
CREB3L1 is a metastasis suppressor that represses expression of genes regulating metastasis, invasion, and angiogenesis. Mellor P, Deibert L, Calvert B, Bonham K, Carlsen SA, Anderson DH Mol Cell Biol
Sirt6 regulates postnatal growth plate differentiation and proliferation via Ihh signaling. Piao J, Tsuji K, Ochi H, Iwata M, Koga D, Okawa A, Morita S, Takeda S, Asou Y Sci Rep
Fli1 deficiency contributes to the suppression of endothelial CXCL5 expression in systemic sclerosis. Ichimura Y, Asano Y, Akamata K, Takahashi T, Noda S, Taniguchi T, Toyama T, Aozasa N, Sumida H, Kuwano Y, Yanaba K, Tada Y, Sugaya M, Sato S, Kadono T Arch Dermatol Res
ChIP-seq analysis of histone H3K9 trimethylation in peripheral blood mononuclear cells of membranous nephropathy patients. Sui WG, He HY, Yan Q, Chen JJ, Zhang RH, Dai Y Braz J Med Biol Res
A circadian clock gene, Rev-erba, modulates the inflammatory function of macrophages through the negative regulation of Ccl2 expression. Sato S, Sakurai T, Ogasawara J, Takahashi M, Izawa T, Imaizumi K, Taniguchi N, Ohno H, Kizaki T J Immunol
Decreased interleukin-20 expression in scleroderma skin contributes to cutaneous fibrosis. Kudo H, Jinnin M, Asano Y, Trojanowska M, Nakayama W, Inoue K, Honda N, Kajihara I, Makino K, Fukushima S, Ihn H Arthritis Rheumatol
Histone deacetylase inhibition promotes fibroblast apoptosis and ameliorates pulmonary fibrosis in mice. Sanders YY, Hagood JS, Liu H, Zhang W, Ambalavanan N, Thannickal VJ Eur Respir J
Hepatitis B virus X protein accelerates hepatocarcinogenesis with partner survivin through modulating miR-520b and HBXIP. Zhang W, Lu Z, Kong G, Gao Y, Wang T, Wang Q, Cai N, Wang H, Liu F, Ye L, Zhang X Mol Cancer
Transcriptional control of ROS homeostasis by KUODA1 regulates cell expansion during leaf development. Lu D, Wang T, Persson S, Mueller-Roeber B, Schippers JH Nat Commun
Angiotensin II activates signal transducer and activators of transcription 3 via Rac1 in atrial myocytes and fibroblasts: implication for the therapeutic effect of statin in atrial structural remodeling. Tsai CT, Lai LP, Kuo KT, Hwang JJ, Hsieh CS, Hsu KL, Tseng CD, Tseng YZ, Chiang FT, Lin JL Circulation
Mir-509-5p joins the Mdm2/p53 feedback loop and regulates cancer cell growth. Ren ZJ, Nong XY, Lv YR, Sun HH, An PP, Wang F, Li X, Liu M, Tang H Cell Death Dis
A possible contribution of endothelial CCN1 downregulation due to Fli1 deficiency to the development of digital ulcers in systemic sclerosis. Saigusa R, Asano Y, Taniguchi T, Yamashita T, Takahashi T, Ichimura Y, Toyama T, Tamaki Z, Tada Y, Sugaya M, Kadono T, Sato S Exp Dermatol
The oncoprotein HBXIP enhances migration of breast cancer cells through increasing filopodia formation involving MEKK2/ERK1/2/Capn4 signaling. Li Y, Zhang Z, Zhou X, Li L, Liu Q, Wang Z, Bai X, Zhao Y, Shi H, Zhang X, Ye L Cancer Lett
Sex-dependent regulation of hepatic CYP3A by growth hormone: Roles of HNF6, C/EBPα, and RXRα Li J, Wan Y, Na S, Liu X, Dong G, Yang Z, Yang J, Yue J Biochem Pharmacol
Fli1 haploinsufficiency induces fibrosis, vascular activation and immune abnormalities resembling systemic sclerosis in bleomycin-treated mice. Taniguchi T, Asano Y, Akamata K, Noda S, Takahashi T, Ichimura Y, Toyama T, Trojanowska M, Sato S Arthritis Rheumatol
Interactive actions of Bdnf methylation and cell metabolism for building neural resilience under the influence of diet. Tyagi E, Zhuang Y, Agrawal R, Ying Z, Gomez-Pinilla F Neurobiol Dis
NNK, a Tobacco-Specific Carcinogen, Inhibits the Expression of Lysyl Oxidase, a Tumor Suppressor. Cheng G, Li J, Zheng M, Zhao Y, Zhou J, Li W Int J Environ Res Public Health
Effect of angiotensin II on STAT3 mediated atrial structural remodeling. Zheng LY, Zhang MH, Xue JH, Li Y, Nan Y, Li MJ, Wang J, Du XP Eur Rev Med Pharmacol Sci
Increased expression of chemerin in endothelial cells due to Fli1 deficiency may contribute to the development of digital ulcers in systemic sclerosis. Akamata K, Asano Y, Taniguchi T, Yamashita T, Saigusa R, Nakamura K, Noda S, Aozasa N, Toyama T, Takahashi T, Ichimura Y, Sumida H, Tada Y, Sugaya M, Kadono T, Sato S Rheumatology (Oxford)
EZH2 Inhibitor Efficacy in Non-Hodgkin's Lymphoma Does Not Require Suppression of H3K27 Monomethylation. Bradley WD, Arora S, Busby J, Balasubramanian S, Gehling VS, Nasveschuk CG, Vaswani RG, Yuan CC, Hatton C, Zhao F, Williamson KE, Iyer P, Méndez J, Campbell R, Cantone N, Garapaty-Rao S, Audia JE, Cook AS, Dakin LA, Albrecht BK, Harmange JC, Daniels DL, Cummings RT, Bryant BM, Normant E, Trojer P Chem Biol
A possible contribution of lipocalin-2 to the development of dermal fibrosis, pulmonary vascular involvement, and renal dysfunction in systemic sclerosis. Takahashi T, Asano Y, Noda S, Aozasa N, Akamata K, Taniguchi T, Ichimura Y, Toyama T, Sumida H, Kuwano Y, Tada Y, Sugaya M, Kadono T, Sato S Br J Dermatol
The Core Promoter and Redox-sensitive <i>Cis</i>-elements as Key Targets for Inactivation of the Lysyl Oxidase Gene by Cadmium. Li J, Cheng G, Zheng M, Zhao Y, Zhou J, Li W J Nat Sci
Synergic chemoprevention with dietary carbohydrate restriction and supplementation of AMPK-activating phytochemicals: the role of SIRT1. Lee JD, Choi MA, Ro SW, Yang WI, Cho AE, Ju HL, Baek S, Chung SI, Kang WJ, Yun M, Park JH Eur J Cancer Prev
Endothelin receptor blockade ameliorates vascular fragility in endothelial cell-specific Fli1 knockout mice by increasing Fli1 DNA-binding ability. Akamata K, Asano Y, Yamashita T, Noda S, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Trojanowska M, Sato S Arthritis Rheumatol
Translocation of forkhead box O1 to the nuclear periphery induces histone modifications that regulate transcriptional repression of PCK1 in HepG2 cells. Arai T, Kano F, Murata M Genes Cells
The Oncoprotein HBXIP Modulates the Feedback Loop of MDM2/p53 to Enhance the Growth of Breast Cancer. Li H, Liu Q, Wang Z, Fang R, Shen Y, Cai X, Gao Y, Li Y, Zhang X, Ye L J Biol Chem
Molecular hydrogen attenuates hypoxia/reoxygenation injury of intrahepatic cholangiocytes by activating Nrf2 expression. Yu J, Zhang W, Zhang R, Jiang G, Tang H, Ruan X, Ren P, Lu B Toxicol Lett
Progranulin overproduction due to Fli1 deficiency contributes to the resistance of dermal fibroblasts to tumor necrosis factor α in systemic sclerosis. Ichimura Y, Asano Y, Akamata K, Noda S, Taniguchi T, Takahashi T, Toyama T, Tada Y, Sugaya M, Sato S, Kadono T Arthritis Rheumatol
Fli1 deficiency contributes to the downregulation of endothelial protein C receptor in systemic sclerosis: a possible role in pro-thrombotic condition. Saigusa R, Asano Y, Yamashita T, Taniguchi T, Takahashi T, Ichimura Y, Toyama T, Yoshizaki A, Miyagaki T, Sugaya M, Sato S Br J Dermatol
DNA Methyltransferase 1 Drives Transcriptional Down-Modulation of β Catenin Antagonist Chibby1 Associated With the BCR-ABL1 Gene of Chronic Myeloid Leukemia. Leo E, Mancini M, Castagnetti F, Gugliotta G, Santucci MA, Martinelli G J Cell Biochem
Alpha-fetoprotein activates AKT/mTOR signaling to promote CXCR4 expression and migration of hepatoma cells. Zhu M, Guo J, Xia H, Li W, Lu Y, Dong X, Chen Y, Xie X, Fu S, Li M Oncoscience
Histone methylation levels correlate with TGFBIp and extracellular matrix gene expression in normal and granular corneal dystrophy type 2 corneal fibroblasts. Maeng YS, Lee GH, Choi SI, Kim KS, Kim EK BMC Med Genomics
A potential contribution of altered cathepsin L expression to the development of dermal fibrosis and vasculopathy in systemic sclerosis. Yamashita T, Asano Y, Taniguchi T, Nakamura K, Saigusa R, Takahashi T, Ichimura Y, Toyama T, Yoshizaki A, Miyagaki T, Sugaya M, Sato S Exp Dermatol
Lower expression of activating transcription factors 3 and 4 correlates with shorter progression-free survival in multiple myeloma patients receiving bortezomib plus dexamethasone therapy. Narita T, Ri M, Masaki A, Mori F, Ito A, Kusumoto S, Ishida T, Komatsu H, Iida S Blood Cancer J
A double-negative feedback loop between EZH2 and miR-26a regulates tumor cell growth in hepatocellular carcinoma Zhuang C, Pei Wang, Da Huang, Luming Xu, Xiaobei Wang, Lin Wang, Lihua Hu Int J Oncol
HBXIP and LSD1 Scaffolded by lncRNA Hotair Mediate Transcriptional Activation by c-Myc. Li Y, Wang Z, Shi H, Li H, Li L, Fang R, Cai X, Liu B, Zhang X, Ye L Cancer Res
The oncoprotein HBXIP up-regulates FGF4 through activating transcriptional factor Sp1 to promote the migration of breast cancer cells. Shi H, Li Y, Feng G, Li L, Fang R, Wang Z, Qu J, Ding P, Zhang X, Ye L Biochem Biophys Res Commun
BDNF rs6265 methylation and genotype interact on risk for schizophrenia. Ursini G, Cavalleri T, Fazio L, Angrisano T, Iacovelli L, Porcelli A, Maddalena G, Punzi G, Mancini M, Gelao B, Romano R, Masellis R, Calabrese F, Rampino A, Taurisano P, Giorgio AD, Keller S, Tarantini L, Sinibaldi L, Quarto T, Popolizio T, Caforio G, Blasi G, Riva MA, Blasi A, Chiariotti L, Bollati V, Bertolino A Epigenetics
ICP4-induced miR-101 attenuates HSV-1 replication. Wang X, Diao C, Yang X, Yang Z, Liu M, Li X, Tang H Sci Rep
Cyclical DNA Methylation and Histone Changes Are Induced by LPS to Activate COX-2 in Human Intestinal Epithelial Cells. Angrisano T, Pero R, Brancaccio M, Coretti L, Florio E, Pezone A, Calabrò V, Falco G, Keller S, Lembo F, Avvedimento VE, Chiariotti L PLoS One
Nuclear transportation of exogenous epidermal growth factor receptor and androgen receptor via extracellular vesicles. Read J, Ingram A, Al Saleh HA, Platko K, Gabriel K, Kapoor A, Pinthus J, Majeed F, Qureshi T, Al-Nedawi K Eur J Cancer
A potential contribution of antimicrobial peptide LL-37 to tissue fibrosis and vasculopathy in systemic sclerosis. Takahashi T, Asano Y, Nakamura K, Yamashita T, Saigusa R, Ichimura Y, Toyama T, Taniguchi T, Yoshizaki A, Tamaki Z, Tada Y, Sugaya M, Kadono T, Sato S Br J Dermatol
Histone Acetylation Regulation in Sleep Deprivation-Induced Spatial Memory Impairment. Duan R, Liu X, Wang T, Wu L, Gao X, Zhang Z Neurochem Res
p-CREB-1 promotes hepatic fibrosis through the transactivation of transforming growth factor-β1 expression in rats. Wang P, Deng L, Zhuang C, Cheng C, Xu K Int J Mol Med
MiR-548an, transcriptionally downregulated by HIF-1α/HDAC1, suppresses tumorigenesis of pancreatic cancer by targeting vimentin expression. Zhu S, He C, Deng S, Li X, Cui S, Zeng Z, Liu M, Zhao S, Chen J, Jin Y, Chen H, Deng S, Liu Y, Wang C, Zhao G Mol Cancer Ther
A novel role of microRNA 17-5p in the modulation of circadian rhythm. Gao Q, Zhou L, Yang SY, Cao JM Sci Rep
Curcumin prevents adriamycin-induced nephropathy MCP-1 expression through blocking histone acetylation Liu J, Fang Zhong, Qin Dai, Lili Xu, Weiming Wang, Nan Chen Int J Clin Exp Med
Regulation of DEK expression by AP-2α and methylation level of DEK promoter in hepatocellular carcinoma. Qiao MX, Li C, Zhang AQ, Hou LL, Yang J, Hu HG Oncol Rep
STAT3-induced WDR1 overexpression promotes breast cancer cell migration. Lee JH, Kim JE, Kim BG, Han HH, Kang S, Cho NH Cell Signal
XAB2 functions in mitotic cell cycle progression via transcriptional regulation of CENPE. Hou S, Li N, Zhang Q, Li H, Wei X, Hao T, Li Y, Azam S, Liu C, Cheng W, Jin B, Liu Q, Li M, Lei H Cell Death Dis
EX4 stabilizes and activates Nrf2 via PKCδ, contributing to the prevention of oxidative stress-induced pancreatic beta cell damage Mi-Hwi Kima, Eung-Hwi Kima, Hye Seung Jungc, Dongki Yangd, Eun-Young Parke, Hee-Sook Juna Science Direct
Upregulation of microRNA-574-3p in a human gastric cancer cell line AGS by TGF-β1. Zhang R, Wang M, Sui P, Ding L, Yang Q Gene
Alteration of histone H3K4 methylation in glomerular podocytes associated with proteinuria in patients with membranous nephropathy. Fujino T, Hasebe N BMC Nephrol
Nuclear Factor of κB1 Is a Key Regulator for the Transcriptional Activation of Milk Synthesis in Bovine Mammary Epithelial Cells. Huang X, Zang Y, Zhang M, Yuan X, Li M, Gao X DNA Cell Biol
Vitamin C down-regulate apo(a) expression via Tet2-dependent DNA demethylation in HepG2 cells. Qu K, Ma XF, Li GH, Zhang H, Liu YM, Zhang K, Zeng JF, Lei JJ, Wei DH, Wang Z Int J Biol Macromol
Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, Ichimura Y, Toyama T, Taniguchi T, Akamata K, Noda S, Yoshizaki A, Tsuruta D, Trojanowska M, Sato S J Exp Med
Mechanical compression induces VEGFA overexpression in breast cancer via DNMT3A-dependent miR-9 downregulation. Kim BG, Gao MQ, Kang S, Choi YP, Lee JH, Kim JE, Han HH, Mun SG, Cho NH Cell Death Dis
Linc00152 promotes cancer progression in hepatitis B virus-associated hepatocellular carcinoma. Deng X, Zhao XF, Liang XQ, Chen R, Pan YF, Liang J Biomed Pharmacother
The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic proteins via PPARα down-regulation. Na S, Li J, Zhang H, Li Y, Yang Z, Zhong Y, Dong G, Yang J, Yue J Toxicology
Defining Epigenetic Regulation of the Interleukin-9 Gene by Chromatin Immunoprecipitation. Skapenko A, Schulze-Koops H Methods Mol Biol
Fli1 Deficiency Induces CXCL6 Expression in Dermal Fibroblasts and Endothelial Cells, Contributing to the Development of Fibrosis and Vasculopathy in Systemic Sclerosis. Taniguchi T, Asano Y, Nakamura K, Yamashita T, Saigusa R, Ichimura Y, Takahashi T, Toyama T, Yoshizaki A, Sato S J Rheumatol
Coenzyme Q10 Improves Lipid Metabolism and Ameliorates Obesity by Regulating CaMKII-Mediated PDE4 Inhibition. Xu Z, Huo J, Ding X, Yang M, Li L, Dai J, Hosoe K, Kubo H, Mori M, Higuchi K, Sawashita J Sci Rep
BRG1 promotes VEGF-A expression and angiogenesis in human colorectal cancer cells. Lan J, Li H, Luo X, Hu J, Wang G Exp Cell Res
Sulfur dioxide suppresses inflammatory response by sulfenylating NF-κB p65 at cysteine 38 in a rat model of acute lung injury. Chen S, Huang Y, Liu Z, Yu W, Zhang H, Li K, Yu X, Tang C, Zhao B, Du J, Jin H Clin Sci (Lond)
A possible implication of reduced levels of LIF, LIFR, and gp130 in vasculopathy related to systemic sclerosis. Taniguchi T, Miyagawa T, Tamaki Z, Nakamura K, Yamashita T, Saigusa R, Takahashi T, Toyama T, Ichimura Y, Yoshizaki A, Tada Y, Sugaya M, Kadono T, Sato S, Asano Y Arch Dermatol Res
HTLV-1 bZIP factor suppresses TDP1 expression through inhibition of NRF-1 in adult T-cell leukemia. Takiuchi Y, Kobayashi M, Tada K, Iwai F, Sakurada M, Hirabayashi S, Nagata K, Shirakawa K, Shindo K, Yasunaga JI, Murakawa Y, Rajapakse V, Pommier Y, Matsuoka M, Takaori-Kondo A Sci Rep
Glucocorticoids suppressing the browning of adipose tissue via miR-19b in male mice. Lv Y, Yu J, Sheng Y, Huang M, Kong X, Di W, Liu J, Zhou H, Liang H, Ding G Endocrinology
Sox5 contributes to prostate cancer metastasis and is a master regulator of TGF-β-induced epithelial mesenchymal transition through controlling Twist1 expression. Hu J, Tian J, Zhu S, Sun L, Yu J, Tian H, Dong Q, Luo Q, Jiang N, Niu Y, Shang Z Br J Cancer
Diallyl disulphide inhibits apolipoprotein(a) expression in HepG2 cells through the MEK1-ERK1/2-ELK-1 pathway. Ma X, Liu Y, Tan Y, Qu K, He X, Zhang H, Wang Z Lipids Health Dis
Sumoylation of histone deacetylase 1 regulates MyoD signaling during myogenesis. Joung H, Kwon S, Kim KH, Lee YG, Shin S, Kwon DH, Lee YU, Kook T, Choe N, Kim JC, Kim YK, Eom GH, Kook H Exp Mol Med
Sox5 is involved in germ-cell regulation and sex determination in medaka following co-option of nested transposable elements. Schartl M, Schories S, Wakamatsu Y, Nagao Y, Hashimoto H, Bertin C, Mourot B, Schmidt C, Wilhelm D, Centanin L, Guiguen Y, Herpin A BMC Biol
Brg1 promotes liver fibrosis via activation of hepatic stellate cells. Li H, Lan J, Han C, Guo K, Wang G, Hu J, Gong J, Luo X, Cao Z Exp Cell Res
Fli1-haploinsufficient dermal fibroblasts promote skin-localized transdifferentiation of Th2-like regulatory T cells. Saigusa R, Asano Y, Taniguchi T, Hirabayashi M, Nakamura K, Miura S, Yamashita T, Takahashi T, Ichimura Y, Toyama T, Yoshizaki A, Trojanowska M, Sato S Arthritis Res Ther
The involvement of PPARs in the selective regulation of brain CYP2D by growth hormone. Zhang F, Li J, Na S, Wu J, Yang Z, Xie X, Wan Y, Li K, Yue J Neuroscience
Histone deacetylase-mediated regulation of endolysosomal pH. Prasad H, Rao R J Biol Chem
HBX protein promotes LASP-1 expression through activation of c-Jun in human hepatoma cells. You H, Kong F, Zhou K, Wei X, Hu L, Hu W, Luo W, Kou Y, Liu X, Chen X, Zheng K, Tang R J Cell Physiol
Sp1-regulated transcription of RasGRP1 promotes HCC proliferation. Zhang X, Zhuang H, Han F, Shao X, Liu Y, Ma X, Wang Z, Qiang Z, Li Y Liver Int
The Protective Role of Brain CYP2J in Parkinson’s Disease Models Yueran Li, Jinhua Wu, Xuming Yu, et al. Oxidative Medicine and Cellular Longevity
Nucleosome positioning and gene regulation of the<i> SGLT2 </i> gene in the renal proximal tubular epithelial cells. Takesue H, Hirota T, Tachimura M, Tokashiki A, Ieiri I Mol Pharmacol
Computational Analysis of Transcriptional Regulation Sites at the HTT Gene Locus. De Souza RAG, Kosior N, Thomson SB, Mathelier A, Zhang AW, Bečanović K, Wasserman WW, Leavitt BR J Huntingtons Dis
The effects of ultrasound exposure on P-glycoprotein-mediated multidrug resistance in vitro and in vivo. Huang C, Huang S, Li H, Li X, Li B, Zhong L, Wang J, Zou M, He X, Zheng H, Si X, Liao W, Liao Y, Yang L, Bin J J Exp Clin Cancer Res
Sodium Citrate Increases Expression and Flux of Mg2+ Transport Carriers Mediated by Activation of MEK/ERK/c-Fos Pathway in Renal Tubular Epithelial Cells. Takashina Y, Manabe A, Hasegawa H, Matsunaga T, Endo S, Ikari A Nutrients
Oncogenic HBXIP enhances ZEB1 through Sp1 to accelerate breast cancer growth. Jiang Y, Wang D, Ren H, Shi Y, Gao Y Thorac Cancer
Comparing effects of CDK inhibition and E2F1/2 ablation on neuronal cell death pathways in vitro and after traumatic brain injury. Aubrecht TG, Faden AI, Sabirzhanov B, Glaser EP, Roelofs BA, Polster BM, Makarevich O, Stoica BA Cell Death Dis
Knockdown of long non-coding HOTAIR enhances the sensitivity to progesterone in endometrial cancer by epigenetic regulation of progesterone receptor isoform B. Chi S, Liu Y, Zhou X, Feng D, Xiao X, Li W, Zhao Y, Wang H Cancer Chemother Pharmacol
Upregulation of transient receptor potential melastatin 6 channel expression by rosiglitazone and all-trans-retinoic acid in erlotinib-treated renal tubular epithelial cells. Manabe A, Furukawa C, Hasegawa H, Matsunaga T, Endo S, Ikari A J Cell Physiol
Fibronectin fragment inhibits xylosyltransferase-1 expression by regulating Sp1/Sp3-dependent transcription in articular chondrocytes. Hwang HS, Lee MH, Kim HA Osteoarthritis Cartilage
Cyanidin Increases the Expression of Mg2+ Transport Carriers Mediated by the Activation of PPARα in Colonic Epithelial MCE301 Cells. Takashina Y, Manabe A, Tabuchi Y, Ikari A Nutrients
Bortezomib-inducible long non-coding RNA myocardial infarction associated transcript is an oncogene in multiple myeloma that suppresses miR-29b. Fu Y, Liu X, Zhang F, Jiang S, Liu J, Luo Y Cell Death Dis
Interaction of BRAF-induced ETS factors with mutant TERT promoter in papillary thyroid cancer. Song YS, Yoo SK, Kim HH, Jung G, Oh AR, Cha JY, Kim SJ, Cho SW, Lee KE, Seo JS, Park YJ Endocr Relat Cancer
SP1-mediated overexpression of lncRNA LINC01234 as a ceRNA facilitates non-small-cell lung cancer progression via regulating OTUB1. Xie JJ, Guo QY, Jin JY, Jin D J Cell Physiol
The DNA endonuclease Mus81 regulates ZEB1 expression and serves as a target of BET4 inhibitors in gastric cancer. Yin Y, Liu W, Shen Q, Zhang P, Wang L, Tao R, Li H, Ma X, Zeng X, Cheong JH, Song S, Ajani JA, Mills GB, Tao K, Peng G Mol Cancer Ther
Breast cancer invasion and progression by MMP-9 through Ets-1 transcription factor. Nazir SU, Kumar R, Singh A, Khan A, Tanwar P, Tripathi R, Mehrotra R, Hussain S Gene
MiR-4429 prevented gastric cancer progression through targeting METTL3 to inhibit m6A-caused stabilization of SEC62. He H, Wu W, Sun Z, Chai L Biochem Biophys Res Commun
Compression-induced expression of glycolysis genes in CAFs correlates with EMT and angiogenesis gene expression in breast cancer. Kim BG, Sung JS, Jang Y, Cha YJ, Kang S, Han HH, Lee JH, Cho NH Commun Biol
Transcription factor E2F4 is a positive regulator of milk biosynthesis and proliferation of bovine mammary epithelial cells. Zhen Z, Zhang M, Yuan X, Li M Cell Biol Int
The NF-κB-modulated miR-19a-3p enhances malignancy of human ovarian cancer cells through inhibition of IGFBP-3 expression. Bai R, Cui Z, Ma Y, Wu Y, Wang N, Huang L, Yao Q, Sun J Mol Carcinog
Long noncoding RNA GAS5 induces abdominal aortic aneurysm formation by promoting smooth muscle apoptosis. He X, Wang S, Li M, Zhong L, Zheng H, Sun Y, Lai Y, Chen X, Wei G, Si X, Han Y, Huang S, Li X, Liao W, Liao Y, Bin J Theranostics
UVB-induced DHODH upregulation, which is driven by STAT3, is a promising target for chemoprevention and combination therapy of photocarcinogenesis. Hosseini M, Dousset L, Michon P, Mahfouf W, Muzotte E, Bergeron V, Bortolotto D, Rossignol R, Moisan F, Taieb A, Bouzier-Sore AK, Rezvani HR Oncogenesis
Berberine Induces CYP2J2 Expression in Human U251 Glioma Cells via Regulation of Peroxisome Proliferator-Activated Receptor Alpha. Yu X, Wang S, Wang J, Gong J, Shi J, Yu S Pharmacology
Circular RNA circ-FOXP1 induced by SOX9 promotes hepatocellular carcinoma progression via sponging miR-875-3p and miR-421. Wang W, Li Y, Li X, Liu B, Han S, Li X, Zhang B, Li J, Sun S Biomed Pharmacother
YY1-mediated overexpression of long noncoding RNA MCM3AP-AS1 accelerates angiogenesis and progression in lung cancer by targeting miR-340-5p/KPNA4 axis. Li X, Yu M, Yang C J Cell Biochem
Functional characterization of a HD-ZIP IV transcription factor NtHDG2 in regulating flavonols biosynthesis in Nicotiana tabacum. Wang Z, Wang S, Xiao Y, Li Z, Wu M, Xie X, Li H, Mu W, Li F, Liu P, Wang R, Yang J Plant Physiol Biochem
Krüppel-like factor 9 promotes neuroblastoma differentiation via targeting the sonic hedgehog signaling pathway. Chen S, Gu S, Xu M, Mei D, Xiao Y, Chen K, Yan Z Pediatr Blood Cancer
YAP1 plays a key role of the conversion of normal fibroblasts into cancer-associated fibroblasts that contribute to prostate cancer progression. Shen T, Li Y, Zhu S, Yu J, Zhang B, Chen X, Zhang Z, Ma Y, Niu Y, Shang Z J Exp Clin Cancer Res
Pterostilbene Attenuates Fructose-Induced Myocardial Fibrosis by Inhibiting ROS-Driven Pitx2c/miR-15b Pathway Kang, L.L. et al. Oxidative Medicine and Cellular Longevity
SIRT1 decreases emotional pain vulnerability with associated CaMKIIα deacetylation in central amygdala. Zhou C, Wu Y, Ding X, Shi N, Cai Y, Pan ZZ J Neurosci
Metformin alleviates breast cancer through targeting high-mobility group AT-hook 2. Li Y, Wang D, Ren H, Feng W Thorac Cancer
Regulatory loop between lncRNA FAS-AS1 and DNMT3b controls FAS expression in hydroquinone-treated TK6 cells and benzene-exposed workers Yuan Q et. al. Environmental Pollution
Glucocorticoids disrupt skeletal angiogenesis through transrepression of NF-κB-mediated preosteoclast Pdgfb transcription in young mice. Peng Y, Lv S, Li Y, Zhu J, Chen S, Zhen G, Cao X, Wu S, Crane JL J Bone Miner Res
Hedgehog signalling mediates drug resistance through targeting TAP1 in hepatocellular carcinoma. Zhou XT, Ding J, Li HY, Zuo JL, Ge SY, Jia HL, Wu J J Cell Mol Med
The regulation of acetylation and stability of HMGA2 via the HBXIP-activated Akt-PCAF pathway in promotion of esophageal squamous cell carcinoma growth. Wu Y, Wang X, Xu F, Zhang L, Wang T, Fu X, Jin T, Zhang W, Ye L Nucleic Acids Res
Aspirin-targeted PD-L1 in lung cancer growth inhibition. Zhang Y, Lv C, Dong Y, Yang Q Thorac Cancer
TCDD-induced antagonism of MEHP-mediated migration and invasion partly involves aryl hydrocarbon receptor in MCF7 breast cancer cells Shan A. et. al. Journal of Hazardous Materials
The Conserved and Particular Roles of R2R3-MYB Regulator FhPAP1 from Freesia hybrida in Flower Anthocyanin Biosynthesis. Li Y, Shan X, Tong L, Wei C, Lu K, Li S, Kimani S, Wang S, Wang L, Gao X Plant Cell Physiol
SP1-Mediated Upregulation of lncRNA LINC01614 Functions a ceRNA for miR-383 to Facilitate Glioma Progression Through Regulation of ADAM12. Wang H, Wu J, Guo W Onco Targets Ther
Survivin Regulates Bad Gene Expression by Binding to Its Promoter and Modulates Cell Cycle and Apoptosis in Esophageal Carcinoma Cell. Chen Y, Bieerkehazhi S, Li X, Ma L, Yibulayin W, Ran J J Oncol
Systematic analysis reveals a functional role for STAMBPL1 in the epithelial-mesenchymal transition process across multiple carcinomas. Ambroise G, Yu TT, Zhang B, Kacal M, Hao Y, Queiroz AL, Ouchida AT, Lindskog C, Norberg E, Vakifahmetoglu-Norberg H Br J Cancer
Altered properties of endothelial cells and mesenchymal stem cells underlying the development of scleroderma-like vasculopathy in Klf5+/-;Fli1+/- mice. Nakamura K, Taniguchi T, Hirabayashi M, Yamashita T, Saigusa R, Miura S, Takahashi T, Toyama T, Ichimura Y, Yoshizaki A, Trojanowska M, Fujiu K, Nagai R, Sato S, Asano Y Arthritis Rheumatol
Mithramycin selectively attenuates DNA-damage-induced neuronal cell death. Makarevich O, Sabirzhanov B, Aubrecht TG, Glaser EP, Polster BM, Henry RJ, Faden AI, Stoica BA Cell Death Dis
lncRNA OTUD6B-AS1 Exacerbates As2O3-Induced Oxidative Damage in Bladder Cancer via miR-6734-5p-Mediated Functional Inhibition of IDH2 Wang Y. et. al. Oxidative Medicine and Cellular Longevity
NtMYB12a acts downstream of sucrose to inhibit fatty acid accumulation by targeting lipoxygenase and SFAR genes in tobacco. Wang Z, Li ZF, Wang SS, Xiao YS, Xie XD, Wu MZ, Yu JL, Cheng LR, Yang AG, Yang J Plant Cell Environ
Lnc NEAT1/miR-29b-3p/Sp1 form a positive feedback loop and modulate bortezomib resistance in human multiple myeloma cells. Che F, Ye X, Wang Y, Ma S, Wang X Eur J Pharmacol
The interplay between ATF2 and NEAT1 contributes to lung adenocarcinoma progression. Liu J, Li K, Wang R, Chen S, Wu J, Li X, Ning Q, Yang G, Pang Y Cancer Cell Int
Unexplored regulatory sequences of divergently paired GLA and HNRNPH2 loci pertinent to Fabry disease in human kidney and skin cells: Presence of an active bidirectional promoter Ibrahim Al-Obaide M. Experimental and Therapeutic Medicine
SNP-adjacent super enhancer network mediates enhanced osteogenic differentiation of MSCs in ankylosing spondylitis. Yu W, Chen K, Ye G, Wang S, Wang P, Li J, Zheng G, Liu W, Lin J, Su Z, Che Y, Ye F, Ma M, Xie Z, Shen H Hum Mol Genet
EZH2 activates CHK1 signaling to promote ovarian cancer chemoresistance by maintaining the properties of cancer stem cells. Wen Y, Hou Y, Yi X, Sun S, Guo J, He X, Li T, Cai J, Wang Z Theranostics
Myostatin Promotes Osteoclastogenesis by Regulating Ccdc50 Gene Expression and RANKL-Induced NF-κB and MAPK Pathways Zhi X. et. al. Front. Pharmacol
IRF4 overexpression promotes the transdifferentiation of tregs into macrophage-like cells to inhibit the development of colon cancer. Wang J, Li S, Li H, Zhou X, Wen H, Lai B Cancer Cell Int
ATF3 downmodulates its new targets IFI6 and IFI27 to suppress the growth and migration of tongue squamous cell carcinoma cells. Xu L, Zu T, Li T, Li M, Mi J, Bai F, Liu G, Wen J, Li H, Brakebusch C, Wang X, Wu X PLoS Genet
Genomic Space of MGMT in Human Glioma Revisited: Novel Motifs, Regulatory RNAs, NRF1, 2, and CTCF Involvement in Gene Expression Ibrahim Al-Obaide M. et.al. Int. J. Mol. Sci
SRF is a nonhistone methylation target of KDM2B and SET7 in the regulation of skeletal muscle differentiation. Kwon DH, Kang JY, Joung H, Kim JY, Jeong A, Min HK, Shin S, Lee YG, Kim YK, Seo SB, Kook H Exp Mol Med
EARLY BUD-BREAK 1 and EARLY BUD-BREAK 3 control resumption of poplar growth after winter dormancy. Azeez A, Zhao YC, Singh RK, Yordanov YS, Dash M, Miskolczi P, Stojkovič K, Strauss SH, Bhalerao RP, Busov VB Nat Commun
Limb expression 1-like (LIX1L) protein promotes cholestatic liver injury by regulating bile acid metabolism. Li J, Zhu X, Zhang M, Zhang Y, Ye S, Leng Y, Yang T, Kong L, Zhang H J Hepatol
c-Myc-induced circ-NOTCH1 promotes aggressive phenotypes of nasopharyngeal carcinoma cells by regulating the miR-34c-5p/c-Myc axis. Huang W, Song W, Jiang Y, Chen L, Lu H Cell Biol Int
The transcription factor Sox7 modulates endocardiac cushion formation contributed to atrioventricular septal defect through Wnt4/Bmp2 signaling. Hong N, Zhang E, Xie H, Jin L, Zhang Q, Lu Y, Chen AF, Yu Y, Zhou B, Chen S, Yu Y, Sun K Cell Death Dis
Local NF-κB activation promotes parathyroid hormone synthesis and secretion in uremic patients. Mao J, Wang M, Ni L, Gong W, Jiang X, Zhang Q, Zhang M, Wen D, Chen J Endocrinology
OVOL2 inhibits macrophage M2 polarization by regulating IL-10 transcription, and thus inhibits the tumor metastasis by modulating the tumor microenvironment. Wu RS, Lin J, Xing YM, Gao WL, Jiang YX, Chen LX, Zhang XP, Dai ZL Immunol Lett
DDIT3/CHOP promotes autophagy in chondrocytes via SIRT1-AKT pathway. Yang C, Xu X, Dong X, Yang B, Dong W, Luo Y, Liu X, Wu Y, Wang J Biochim Biophys Acta Mol Cell Res
Sulforaphane Ameliorates Diabetes-Induced Renal Fibrosis through Epigenetic Up-Regulation of BMP-7. Kong L, Wang H, Li C, Cheng H, Cui Y, Liu L, Zhao Y Diabetes Metab J
NEAT1 functions as a key mediator of BMP2 to promote osteogenic differentiation of renal interstitial fibroblasts. Zhu Z, Zhang X, Jiang Y, Ruan S, Huang F, Zeng H, Liu M, Xia W, Zeng F, Chen J, Cui Y, Chen H Epigenomics
MKL1/PINK1-AS/miR-34a-5p Regulates ALDOA to Affect Aerobic Glycolysis in Hepatocellular Carcinoma Wang, J. et. al. Research Square
Unexplored regulatory sequences of divergently paired GLA and HNRNPH2 loci pertinent to Fabry disease in human kidney and skin cells: Presence of an active bidirectional promoter. Al-Obaide MAI, Al-Obaidi II, Vasylyeva TL Exp Ther Med
Propofol Protects against Cerebral Ischemia/Reperfusion Injury by Down-Regulating Long Noncoding RNA SNHG14. Sun B, Ou H, Ren F, Guan Y, Huan Y, Cai H ACS Chem Neurosci
Microglia promote autoimmune inflammation via the noncanonical NF-κB pathway. Jie Z, Ko CJ, Wang H, Xie X, Li Y, Gu M, Zhu L, Yang JY, Gao T, Ru W, Tang SJ, Cheng X, Sun SC Sci Adv
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer. Dang F, Nie L, Zhou J, Shimizu K, Chu C, Wu Z, Fassl A, Ke S, Wang Y, Zhang J, Zhang T, Tu Z, Inuzuka H, Sicinski P, Bass AJ, Wei W Nat Commun
An apple (Malus domestica) AP2/ERF transcription factor modulates carotenoid accumulation. Dang Q, Sha H, Nie J, Wang Y, Yuan Y, Jia D Hortic Res
Interleukin-31 promotes fibrosis and T helper 2 polarization in systemic sclerosis. Kuzumi A, Yoshizaki A, Matsuda KM, Kotani H, Norimatsu Y, Fukayama M, Ebata S, Fukasawa T, Yoshizaki-Ogawa A, Asano Y, Morikawa K, Kazoe Y, Mawatari K, Kitamori T, Sato S Nat Commun
LPS‑induced inflammatory response and apoptosis are mediated by Fra‑1 upregulation and binding to YKL‑40 in A549 cells Wang, F. et. al. Experimental and Therapeutic Medicine
DLX6-AS1 activated by H3K4me1 enhanced secondary cisplatin resistance of lung squamous cell carcinoma through modulating miR-181a-5p/miR-382-5p/CELF1 axis. Zhao X, Wang J, Zhu R, Zhang J, Zhang Y Sci Rep
Circular RNA Mitochondrial Translation Optimization 1 homologue (CircMTO1) induced by Zinc Finger Protein 460 (ZNF460) promotes oral squamous cell carcinoma progression through the microRNA miR-320a / Alpha Thalassemia/Mental Retardation, X-linked (ATRX) axis. Zou C, Li X, Lv X, Wu S, Song J, Tang Z, Luo H, Wei H, Ai Y Bioengineered
m6A demethylase ALKBH5 inhibits cell proliferation and the metastasis of colorectal cancer by regulating the FOXO3/miR-21/SPRY2 axis. Wu X, Dai M, Li J, Cai J, Zuo Z, Ni S, Zhang Q, Zhou Z Am J Transl Res
Endothelial CCR6 expression due to FLI1 deficiency contributes to vasculopathy associated with systemic sclerosis. Ikawa T, Miyagawa T, Fukui Y, Toyama S, Omatsu J, Awaji K, Norimatsu Y, Watanabe Y, Yoshizaki A, Sato S, Asano Y Arthritis Res Ther
The contribution of LIGHT to the development of systemic sclerosis by modulating IL-6 and Th1 chemokine expression in dermal fibroblasts. Ikawa T, Ichimura Y, Miyagawa T, Fukui Y, Toyama S, Omatsu J, Awaji K, Norimatsu Y, Watanabe Y, Yoshizaki A, Sato S, Asano Y J Invest Dermatol
Loss of peptidase D binding restores the tumor suppressor functions of oncogenic p53 mutants. Yang L, Li Y, Bhattacharya A, Zhang Y Commun Biol
The Methyltransferase Smyd1 Mediates LPS-Triggered Up-Regulation of IL-6 in Endothelial Cells. Shamloul A, Steinemann G, Roos K, Liem CH, Bernd J, Braun T, Zakrzewicz A, Berkholz J Cells
LncRNA KCNQ1OT1 promotes apoptosis and oxidative stress of human lens epithelial cells through epigenetic regulation of WRN. Jiang S, Jia Y, Gao Z Curr Eye Res
FOXM1 Promotes Malignant Proliferation of Esophageal Squamous Cell Carcinoma Through Transcriptional Activating CDC6. Chen X, Chen J, Yu X, Lin G, Chen T DNA Cell Biol
The rs1001179 SNP and CpG methylation regulate catalase expression in chronic lymphocytic leukemia. Galasso M, Dalla Pozza E, Chignola R, Gambino S, Cavallini C, Quaglia FM, Lovato O, Dando I, Malpeli G, Krampera M, Donadelli M, Romanelli MG, Scupoli MT Cell Mol Life Sci
Transcription factor NtWRKY33a modulates the biosynthesis of polyphenols by targeting NtMYB4 and NtHCT genes in tobacco. Wang Z, Ma L, Liu P, Luo Z, Li Z, Wu M, Xu X, Pu W, Huang P, Yang J Plant Sci
BTN3A1 promotes tumor progression and radiation resistance in esophageal squamous cell carcinoma by regulating ULK1-mediated autophagy. Yang W, Cheng B, Chen P, Sun X, Wen Z, Cheng Y Cell Death Dis
MKL-1-induced PINK1-AS overexpression contributes to the malignant progression of hepatocellular carcinoma via ALDOA-mediated glycolysis. Wang J, Zhang HM, Dai ZT, Huang Y, Liu H, Chen Z, Wu Y, Liao XH Sci Rep
Melatonin-mediated FKBP4 downregulation protects against stress-induced neuronal mitochondria dysfunctions by blocking nuclear translocation of GR. Kim MJ, Choi GE, Chae CW, Lim JR, Jung YH, Yoon JH, Park JY, Han HJ Cell Death Dis
Shc3 facilitates breast cancer drug resistance by interacting with ErbB2 to initiate ErbB2/COX2/MDR1 axis. Liu Y, Cao F, Xia F, Li J, Dong X, Guo Y, Zhang J, Zhao Q, Liu Y Cancer Med
HBXIP blocks myosin-IIA assembly by phosphorylating and interacting with NMHC-IIA in breast cancer metastasis. Zhang L, Zhou X, Liu B, Shi X, Li X, Xu F, Fu X, Wang X, Ye K, Jin T, Sun H, Li Q, Zhang W, Ye L Acta Pharm Sin B
SIRT6-PAI-1 axis is a promising therapeutic target in aging-related bone metabolic disruption. Aobulikasimu A, Liu T, Piao J, Sato S, Ochi H, Okawa A, Tsuji K, Asou Y Sci Rep
PARP-1 inhibits DNMT1-mediated promoter methylation and promotes linc01132 expression in benzene-exposed workers and hydroquinone-induced malignant transformed cells. Zhang H, Jiang F, Ling X, Zhong B, Han Y, Pan Z, Yuan Q, Meng J, Zheng D, Chen X, Zhong Q, Liu L Toxicol Mech Methods
The transcription factor NtERF13a enhances abiotic stress tolerance and phenylpropanoid compounds biosynthesis in tobacco. Wang Z, Yang J, Gao Q, He S, Xu Y, Luo Z, Liu P, Wu M, Xu X, Ma L, Zhang Z, Yang Y, Yang J Plant Sci
MAPK-ERK-CREB signaling pathway upregulates Nav1.6 in oxaliplatin-induced neuropathic pain in the rat. Shao J, Yu W, Wei W, Wang S, Zheng Z, Li L, Sun Y, Zhang J, Li Z, Ren X, Zang W, Cao J Toxicol Lett
A positive feedback loop between miR-574-3p and HIF-1α in promoting angiogenesis under hypoxia. Zhang R, Miao Z, Liu Y, Zhang X, Yang Q Microvasc Res
Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3 to the SSBP1 promoter region. Wang KD, Zhu ML, Qin CJ, Dong RF, Xiao CM, Lin Q, Wei RY, He XY, Zang X, Kong LY, Xia YZ Br J Pharmacol
GATA6 promotes fibrotic repair of tracheal injury through NLRP3 inflammasome-mediated epithelial pyroptosis. Li A, Gu L, He C, Li Y, Peng M, Liao J, Xiao R, Xu L, Guo S Int Immunopharmacol
SETD1A-mediated H3K4me3 methylation upregulates lncRNA HOXC-AS3 and the binding of HOXC-AS3 to EP300 and increases EP300 stability to suppress the ferroptosis of NSCLC cells. Shi Z, Zhang H, Shen Y, Zhang S, Zhang X, Xu Y, Sun D Thorac Cancer
The mesodermal and myogenic specification of hESCs depend on ZEB1 and are inhibited by ZEB2. Ninfali C, Siles L, Esteve-Codina A, Postigo A Cell Rep
Exosomal lncRNA NEAT1 inhibits NK cell activity to promote multiple myeloma cell immune escape via an EZH2/PBX1 axis. Wang QM, Lian GY, Sheng SM, Xu J, Ye LL, Min C, Guo SF Mol Cancer Res
3D Spheroids Facilitate Differentiation of Human Adipose-Derived Mesenchymal Stem Cells into Hepatocyte-Like Cells via p300-Mediated H3K56 Acetylation. Yu Y, Huang H, Ye J, Li Y, Xie R, Zeng L, Huang Y, Zeng T, Luo D, Zhong J, Peng W Stem Cells Transl Med
High glucose environment induces NEDD4 deficiency that impairs angiogenesis and diabetic wound healing. Guo Y, Wang Y, Liu H, Jiang X, Lei S J Dermatol Sci
NtERF4 promotes the biosynthesis of chlorogenic acid and flavonoids by targeting PAL genes in Nicotiana tabacum. He S, Xu X, Gao Q, Huang C, Luo Z, Liu P, Wu M, Huang H, Yang J, Zeng J, Wang Z Planta
Differential effect of cancer-associated fibroblast-derived extracellular vesicles on cisplatin resistance in oral squamous cell carcinoma via miR-876-3p. Kang SH, Oh SY, Lee KY, Lee HJ, Kim MS, Kwon TG, Kim JW, Lee ST, Choi SY, Hong SH Theranostics
TET2-mediated tumor cGAS triggers endothelial STING activation to regulate vasculature remodeling and anti-tumor immunity in liver cancer. Lv H, Zong Q, Chen C, Lv G, Xiang W, Xing F, Jiang G, Yan B, Sun X, Ma Y, Wang L, Wu Z, Cui X, Wang H, Yang W Nat Commun
Murine double minute 2-mediated estrogen receptor 1 degradation activates macrophage migration inhibitory factor to promote vascular smooth muscle cell dedifferentiation and oxidative stress during thoracic aortic aneurysm progression. Liu T, Zhang T, Guo C, Liang X, Wang P, Zheng B Biochim Biophys Acta Mol Cell Res
Enhancer-mediated FOXO3 expression promotes MSC adipogenic differentiation by activating autophagy. Feng P, Pang P, Sun Z, Xie Z, Chen T, Wang S, Cao Q, Mi R, Zeng C, Lu Y, Yu W, Shen H, Wu Y Biochim Biophys Acta Mol Basis Dis
Butyrate enhances erastin-induced ferroptosis of lung cancer cells via modulating the ATF3/SLC7A11 pathway. Bi R, Hu R, Jiang L, Wen B, Jiang Z, Liu H, Mei J Environ Toxicol
Krüppel-like factor 4 (KLF4) facilitates lipid production in immortalized human sebocytes via regulating the expression of SREBP1. Li X, Zeng X, Kim D, Jiang J, Wei F, Zhang J, Chai B, Fu L, Lee Y, Kim C, Chen H Biochem Biophys Res Commun
TRAF3-EWSR1 signaling axis acts as a checkpoint on germinal center responses. Li Y, Zhu L, Ko CJ, Yang JY, Wang H, Manyam G, Wang J, Cheng X, Zhao S, Jie Z J Exp Med
FOSL1 regulates hyperproliferation and NLRP3-mediated inflammation of psoriatic keratinocytes through the NF-kB signaling via transcriptionally activating TRAF3. Liang Y, Han D, Zhang S, Sun L Biochim Biophys Acta Mol Cell Res
TaLBD41 interacts with TaNAC2 to regulate nitrogen uptake and metabolism in response to nitrate availability. Jing Y, Shen C, Li W, Peng L, Hu M, Zhang Y, Zhao X, Teng W, Tong Y, He X New Phytol
HBXIP induces PARP1 via WTAP-mediated m6A modification and CEBPA-activated transcription in cisplatin resistance to hepatoma. Fu XL, Guo SM, Ma JQ, Ma FY, Wang X, Tang YX, Li Y, Zhang WY, Ye LH Acta Pharmacol Sin
Involvement of dysregulated hippocampal histone H3K9 methylation at the promoter of the BDNF gene in impaired memory extinction. Oga K, Fuchikami M, Kobayashi H, Miyagi T, Fujita S, Fujita S, Okada S, Morinobu S Psychopharmacology (Berl)
Enhanced expression of miR-20a driven by nanog exacerbated the degradation of extracellular matrix in thoracic aortic dissection. An Z, Sun Y, Yang X, Zhou J, Yu Y, Zhang B, Xu Z, Zhu Y, Wang G Noncoding RNA Res
NtWIN1 regulates the biosynthesis of scopoletin and chlorogenic acid by targeting NtF6'H1 and NtCCoAMT genes in Nicotiana tabacum. He S, Gao J, Li B, Luo Z, Liu P, Xu X, Wu M, Yang J, He X, Wang Z Plant Physiol Biochem
Interaction of Sp1 and Setd8 promotes vascular smooth muscle cells apoptosis by activating Mark4 in vascular calcification. Li Y, Cheng M, Jin J, Zhang D, Zhang S, Bai Y, Xu J Aging (Albany NY)
Luoshi Neiyi Prescription inhibits estradiol synthesis and inflammation in endometriosis through the HIF1A/EZH2/SF-1 pathway. Wu L, Lan D, Sun B, Su R, Pei F, Kuang Z, Su Y, Lin S, Wang X, Zhang S, Chen X, Jia J, Zeng C J Ethnopharmacol
NtMYB27 acts downstream of NtBES1 to modulate flavonoids accumulation in response to UV-B radiation in tobacco. Wang Z, Luo Z, Li Z, Liu P, He S, Yu S, Zhao H, Yang J, Zhang Z, Cao P, Jin S, Yang Y, Yang J Plant J
MiR-183-5p inhibits lung squamous cell carcinoma survival through disrupting hypoxia adaptation mediated by HIF-1α/NDUFA4L2 axis. Han P, Zhang B, Li Y, Gao R, Li X, Ren H, Shi P, Zhao A, Xue J, Yang A, Liang Y Oncogene
Tet1-mediated activation of the Ampk signaling by Trpv1 DNA hydroxymethylation exerts neuroprotective effects in a rat model of Parkinson's disease. Fan Y, Wang P, Jiang C, Chen J, Zhao M, Liu J Funct Integr Genomics
USP10-mediated deubiquitination of NR3C1 regulates bone homeostasis by controlling CST3 expression. Zhou L, Mu S, Zhang Y, Song H Biochem Pharmacol
Adipocytes Promote Endometrial Cancer Progression Through Activation of the SIRT1-HMMR Signaling Axis. Savardekar A, Fernandes E, Padhye-Pendse A, Gupta T, Pol J, Phadke M, Desai S, Jadhav S, Rajwade J, Banerjee A Mol Carcinog
Osteogenic-Like Microenvironment of Renal Interstitium Induced by Osteomodulin Contributes to Randall's Plaque Formation. Zhu Z, Huang F, Gao M, Liu M, Zhang Y, Tang L, Wu J, Yu H, He C, Chen J, Yang Z, Chen Z, Li Y, Chen H, Lei T, Zeng F, Cui Y Adv Sci (Weinh)
Epigenetic modification of CD4(+) T cells into Tregs by 5-azacytidine as cellular therapeutic for atherosclerosis treatment. Zhu L, Liu Z, Cui Q, Guan G, Hui R, Wang X, Wang J, Zhang Y, Zhu X Cell Death Dis
SP1-mediated transcriptional repression of SFRP5 is correlated with cardiac fibroblast activation and atrial myocyte apoptosis in the development of atrial fibrillation. Sun Y, Hu Z, Han J, Li G Exp Cell Res
BRG1 improves reprogramming efficiency by enhancing glycolytic metabolism. Ren X, Huang S, Xu J, Xue Q, Xu T, Shi D, Ma S, Li X Cell Mol Life Sci
AEBP1 Silencing Protects Against Cerebral Ischemia/Reperfusion Injury by Regulating Neuron Ferroptosis and Microglia M2 Polarization Through PRKCA-PI3K-Akt Axis. Zhang Y, Li Y, Liu F Drug Dev Res
DNMT3a Deficiency Contributes to Anesthesia/Surgery-Induced Synaptic Dysfunction and Cognitive Impairment in Aged Mice. Cong P, Huang X, Zhang Q, He M, Wan H, Wu Q, Wu H, Zhang Y, Cheng C, Tian L, Xiong L Aging Cell
Tumor-derived CCL15 regulates RNA m6A methylation in cancer-associated fibroblasts to promote hepatocellular carcinoma growth. Wang C, Dong D, Zhao N, Liu Y, Bai C, Hua J, Cui R, Wei X, Zhao T, Ji N, Yang S, Zhao J, Li H, Li Y Cancer Lett

 

 

艾美捷科技优势代理品牌

发表评论

:?: :razz: :sad: :evil: :!: :smile: :oops: :grin: :eek: :shock: :???: :cool: :lol: :mad: :twisted: :roll: :wink: :idea: :arrow: :neutral: :cry: :mrgreen: